Abstracts tagged "inflammation and spondylarthritis"

Abstract Number: 591 • ACR/ARHP Annual Meeting 2017
Inflammation on MRI of Spine and Sacroiliac Joints Is Highly Predictive of Structural Damage in Axial Spondyloarthritis: The 5 Years Data of the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Robert B.M. Landewé³, Maxime Dougados⁴ and Désirée van der Heijde¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands, ⁴Paris-Descartes University,, Paris, France
Background/Purpose: The effect of local inflammation on structural damage in patients (pts) with axial spondyloarthritis is not well known. We aimed to test the possible…
Abstract Number: 3037 • ACR/ARHP Annual Meeting 2016
Calprotectin Is Highly Upregulated in Inflamed Axial Entheses in SKG Mice
Zheni Stavre¹, Yukiko Maeda² and Ellen M. Gravallese³, ¹Internal Medicine-Rheumatology, University of Massachusetts Medical School, Worcester, MA, ²Medicine, University of Massachusetts Medical School, Worcester, MA, ³Lazare Research Bldg, University of Massachusetts Medical School, Worcester, MA
Background/Purpose: SKG mice exhibit features of spondyloarthropathy (SpA) and inflammatory bowel disease (IBD). Their SpA-like phenotype is induced by a beta-glucan, curdlan, via the Dectin-1…
Abstract Number: 2060 • ACR/ARHP Annual Meeting 2015
Microscopic Bowel Inflammation in Spondyloarthritis As a Baseline Predictor of Anti-TNF Response
Heleen Cypers, Gaëlle Varkas, Filip van Den Bosch and Dirk Elewaut, Rheumatology, Ghent University Hospital, VIB, Ghent, Belgium
· Background/Purpose: Microscopic bowel inflammation without associated gastro-intestinal symptoms is present in up to 50% of spondyloarthritis (SpA) patients. Two types of inflammation are distinguished based…
Abstract Number: 2499 • ACR/ARHP Annual Meeting 2013
Analysis Of Inflammatory Markers Within Facet Joints Of Patients Within Ankylosing Spondylitis
Uta Syrbe¹, Janine Bleil², Rene Maier³, Heiner Appel¹ and Joachim Sieper⁴, ¹Charité Medical University, Campus Benjamin Franklin, Berlin, Germany, ²Charité, Berlin, Germany, ³Charite, Berlin, Germany, ⁴Charitè Campus Benjamin Franklin, Berlin, Germany
Background/Purpose: Inflammation within sacroiliac joints and within the spine is a hallmark of ankylosing spondylitis (AS). Apart from nonsteroidal anti-rheumatic drug (NSAID) treatment, inhibition of…
Abstract Number: 1539 • ACR/ARHP Annual Meeting 2013
Inflammation In The Posterior Elements Of The Spine Is Infrequent In Patients With Recent Onset Axial Spondyloarthritis, Especially If No Inflammation In The Vertebral Bodies Is Observed
Rosaline van den Berg¹, Manouk de Hooge¹, Monique Reijnierse², Victoria Navarro-Compán¹, Karen Fagerli³, Maureen Turina⁴, Maikel van Oosterhout⁵, Roberta Ramonda⁶, Floris van Gaalen¹, Tom Huizinga¹ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ⁵Rheumatology, GHZ Hospital, Gouda, Netherlands, ⁶Rheumatology Unit, University of Padova, Padova, Italy
Background/Purpose: There is evidence that in almost all patients with longstanding and active ankylosing spondylitis (AS) inflammatory lesions in the posterior elements are as frequent…