Abstracts tagged "inflammation and pain"

Abstract Number: 3091 • 2015 ACR/ARHP Annual Meeting
A Randomized, Controlled Trial of Pregabalin in Adolescent Patients (12-17 years) with Fibromyalgia
Lesley Arnold¹, Lucinda Bateman², Kenneth N. Schikler³, Tahira Khan⁴, Lynne Pauer⁴, Pritha Bhadra Brown⁵, Marci L. Chew⁴, Andrew Clair⁵ and Joseph Scavone⁴, ¹University of Cincinnati, Cincinnati, OH, ²Bateman Horne Center, Salt Lake City, UT, ³Pediatrics, University of Louisville, Louisville, KY, ⁴Pfizer Inc, Groton, CT, ⁵Pfizer Inc., New York, NY
Background/Purpose: :Fibromyalgia (FM) is characterized by chronic widespread pain, sleep disturbance, and fatigue. Pregabalin is approved in the US in adults for the management of…
Abstract Number: 2857 • 2013 ACR/ARHP Annual Meeting
The Role Of FAM173b As a Newly Identified Regulator Of Chronic Pain
Hanneke Willemen¹, Annemiek Kavelaars², Rafael González Cano^1,3, Cobi Heijnen² and Niels Eijkelkamp⁴, ¹NIDOD, UMC Utrecht, Utrecht, Netherlands, ²MD Anderson Cancer Center, Houston, TX, ³Department of pharmacology, University of Granada, Granada, Spain, ⁴Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), UMC Utrecht, Utrecht, Netherlands
Background/Purpose: Chronic pain is a major debilitating problem in many inflammatory diseases including rheumatoid arthritis and osteoarthritis. Pain is an important problem during active disease…
Abstract Number: 1253 • 2013 ACR/ARHP Annual Meeting
Studies On The Relationship Between Intraplantar Carrageenan-Induced Bradykin B1 Receptor Messenger Ribonucleic Acid Expression and Oedema and Hyperalgesia In Rats: Effects Of Dexamethasone and a B1 Receptor Antagonist, BI-113823
Guy Kennett¹, Jessica Arlott¹, Phil Butler², Mike Comer¹, Andrew Clarkson², Alex Coulthard¹, Sean Lightowler¹, Rachel Upcott-Gill², Rebecca Upton¹, Louise Wray², Philipp Wabnitz³, Sven Kühnert³ and Simon Cruwys³, ¹Saretius Ltd, Reading, United Kingdom, ²Cyprotex Ltd, Macclesfield, United Kingdom, ³Grunenthal GmbH, Aachen, Germany
Background/Purpose: Kinins are a group of peptides formed in plasma and tissues in response to infection, tissue trauma or inflammation (inflamm) whose actions are mediated…

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