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Abstracts tagged "inflammation and lung injury"

  • Abstract Number: 46 • ACR/ARHP Annual Meeting 2018

    Organic Dust Inhalants Shift Immune Responses and Extracellular Matrix Balance between Synovium and Lung in the Collagen-Induced Arthritis Mouse Model

    Michael J. Duryee1, Jill Poole2, Amy Nelson3, Katherine Janike2, Lynell W. Klassen4, James R. O'Dell4, Bryant R. England5, Ted R. Mikuls6 and Geoffrey M. Thiele7, 1Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 2Medicine, University of Nebraska Medical Center, Omaha, NE, 3Department of Medicine, University of Nebrasa Medical Center, Omaha, NE, 4Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 5Rheumatology, VA Nebraska-Western Iowa Health Care System & University of Nebraska Medical Center, Omaha, NE, 6Internal Medicine, Division of Rheumatology, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 7University of Nebraska Medical Center, Omaha, NE

    Background/Purpose:   Emerging evidence suggests that the lungs may be an initiating site of autoimmunity leading to RA with organic inhalant exposures such as those…

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