Abstracts tagged "inflammation and CKD-506"

Abstract Number: 8 • 2019 ACR/ARP Annual Meeting
CKD-506, a Selective Histone Deacetylase (HDAC) 6 Inhibitor, Regulates Inflammatory Responses Through NF-kB and AP-1 Signaling
Jieun Shin¹, Nina Ha ¹, Daekwon Bae ¹, Dong-hyeon Suh ¹, Ji-yeon Baek ¹, Jae Hyun Jun ¹, Yong Jae Lee ¹, Young Il Choi ¹, Keun Ho Ryu ¹, Gi Soo Youn ² and Jinseu Park ³, ¹CKD Research Institute, Yongin-si, Republic of Korea, ²Department of Biomedical Science, Hallym University, Chuncheon, Republic of Korea, ³Department of Biomedical Science, Hallym University, Chuncheon
Background/Purpose: Inhibition of HDAC6 has been proposed beneficial and therapeutic effects in inflammatory diseases. CKD-506, a potent and selective oral HDAC6 inhibitor, has anti-inflammatory and…

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Abstracts tagged "inflammation and CKD-506"

CKD-506, a Selective Histone Deacetylase (HDAC) 6 Inhibitor, Regulates Inflammatory Responses Through NF-kB and AP-1 Signaling