Abstracts tagged "inflammasome activation and tumor necrosis factor (TNF)"

Abstract Number: 76 • 2017 ACR/ARHP Annual Meeting
TNF-α Potentiates Uric Acid-Induced Interleukin-1β Secretion in Human Neutrophils
Shuzo Sato¹, Makiko Yashiro¹, Tomoyuki Asano¹, Tomohiro Koga², Eiji Suzuki¹, Hiroko Kobayashi¹, Hiroshi Watanabe¹ and Kiyoshi Migita³, ¹Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan, ²Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Fukushima Medical University School of Medicine, Fukushima, Japan
Background/Purpose: Gout is an inflammatory arthropathy due to the deposition of uric acid (monosodium urate: MSU) crystals in synovial tissue. MSU leads to activate nucleotide-binding…

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Abstracts tagged "inflammasome activation and tumor necrosis factor (TNF)"

TNF-α Potentiates Uric Acid-Induced Interleukin-1β Secretion in Human Neutrophils