Abstracts tagged "Infection"

Abstract Number: 0263 • ACR Convergence 2024
Characteristics and Coinfections of Diffuse Alveolar Hemorrhage in Rheumatic Patients
Eduardo Briones-García¹, Shaul Navarro-Lara², Marco A Ortiz-Bustamante², Iris Paola García Herrera³, Carla M Roman-Montes² and Guillermo A Guaracha-Basañez⁴, ¹Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department., Ciudad de México, Distrito Federal, Mexico, ²Departamento de Infectología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador-Zubirán., México city, Mexico, ³Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ⁴Instituto Nacional de Ciencias Medicas y Nutricion “Salvador Zubirán”, Mexico City, Distrito Federal, Mexico
Background/Purpose: Diffuse alveolar hemorrhage (DAH) is a severe respiratory complication observed in certain rheumatic diseases, such as systemic lupus erythematosus (SLE), ANCA-associated vasculitides (AAV), and…
Abstract Number: 1270 • ACR Convergence 2024
Association of Disease-Modifying Anti-Rheumatic Drug Selection with Hospitalized Infection in Youth with Childhood-Onset Systemic Lupus Erythematosus
Jordan Roberts¹, Anna Faino², Marshall Brown³, Gabrielle Alonzi⁴, Mersine Bryan⁵, Cordelia Burn⁶, Joyce Chang⁴, Jonathan Cogen⁷, Nidhi Naik⁸, Kareena Patel⁹, Emily Zhang⁴, Mary Beth Son¹⁰ and Esi Morgan¹, ¹Seattle Children's Hospital, Seattle, WA, ²Seattle Children's Research Institute, Core for Biostatistics, Epidemiology and Analytics in Research, Seattle, ³Core for Biostatistics, Epidemiology and Analytics in Research, Seattle Children's Research Institute, Seattle, WA, ⁴Boston Children's Hospital, Boston, MA, ⁵Division of Hospital Medicine, Seattle Children's Hospital, Seattle, WA, ⁶Seattle Children's Hospital, Boston Children's Hospital, Seattle, ⁷Seattle Children’s Hospital, Seattle, WA, ⁸Seattle children's hospital, Bothell, WA, ⁹Seattle Children's Hospital, Seattle, ¹⁰Boston Children's Hospital, Brookline, MA
Background/Purpose: Youth with childhood-onset systemic lupus erythematosus (cSLE) have increased risk of serious infection. It is unknown how much of this risk is due to…
Abstract Number: 2417 • ACR Convergence 2024
Frequency and Associated Factors of Herpes Zoster Infection in Systemic Lupus Erythematosus Patients from Latin-America
Romina Nieto¹, Lucia Hernandez², Marina Scolnik³, Gisela Constanza Subils⁴, Veronica Saurit⁵, Verónica Gabriela Savio⁶, Valeria Arturi⁷, Boris Kisluk⁸, Luciana González Lucero⁹, Wilfredo Patiño Grageda¹⁰, María De Los Ángeles Gargiulo¹¹, ODIRLEI MONTICIELO¹², Angela Duarte¹³, Eduardo Borba¹⁴, Luciana Parente¹⁴, Edgard Reis Neto¹⁵, Oscar Neira¹⁶, Gustavo Aroca Martínez¹⁷, Antonio Iglesias Gamarra¹⁸, Paul Méndez-Patarroyo¹⁹, Rafael López²⁰, Margarita Portela Hernandez²¹, Carlos Núñez-Álvarez²², Yelitza González Bello²³, Jorge Isaac Velasco Santos²⁴, Jorge Esquivel-Valerio²⁵, Marcos Vázquez²⁶, Maria Teresa Martinez de Filartiga²⁷, Magaly Alva Linares²⁸, Roberto Muñoz Louis²⁹, Carina Pizzarossa³⁰, Ana Carolina Ralle³¹, María Camila Riascos³², Joaquín Martínez Serventi³³, Graciela Alarcon³⁴, Bernardo Pons-Estel² and Guillermo Pons-Estel³⁵, and Grupo Latinoamericano de Estudio del Lupus (GLADEL), ¹Centro Regional de Enfermedades Autoinmunes y Reumaticas. GO-CREAR, Rosario, Santa Fe, Argentina, ²Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), ROSARIO, Santa Fe, Argentina, ³Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Hospital Italiano de Córdoba, Córdoba, Argentina, ⁵hospital privado universitario de cordoba, Córdoba, Argentina, ⁶Sección de Reumatología, Hospital Córdoba, Córdoba, Argentina, ⁷Hospital HIGA San Martín, La Plata, Argentina, ⁸Unidad de Enfermedades Autoinmunes, Hospital Escuela Eva Perón, Granadero Baigorria, Argentina, ⁹Hospital Padilla, Tucumán, Argentina, ¹⁰Hospital General de Agudos Dr Ramos Mejia, CABA, Argentina, ¹¹Instituto de Investigaciones Médicas Alfredo Lanari, Buenos Aires, Argentina, Buenos Aires, Argentina, ¹²HOSPITAL DE CLINICAS DE PORTO ALEGRE, PORTO ALEGRE, Rio Grande do Sul, Brazil, ¹³Universidad Federal de Pernambuco, Pernambuco, Brazil, ¹⁴Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, ¹⁵Division of Rheumatology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal, São Paulo, SP, Brazil, ¹⁶Hospital del Salvador, Santiago de Chile, Chile, ¹⁷Universidad Simón Bolivar, Barranquilla, Colombia, Barranquilla, Colombia, ¹⁸Clínica de La Costa - Universidad Simón Bolívar Barranquilla, Barranquilla, Colombia, ¹⁹Universidad de Los Andes, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia, ²⁰Servicio de Reumatología. Hospital Luís Vernaza, Guayaquil, Ecuador, Guayaquil, Ecuador, ²¹Departamento de Reumatología del Hospital de especialidades del Centro Médico Nacional Siglo XXI del Instituto Mexicano del Seguro Social (IMSS), Mexico, Mexico, ²²Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, CDMX, Mexico, Mexico, Mexico, ²³Depto. de Inmunología y Reumatología, Hospital General de Occidente y Universidad de Guadalajara, Guadalajara, Mexico, ²⁴Hospital Central Dr. Ignacio Morones Prieto, Potosí, Mexico, ²⁵Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, MONTERREY, Mexico, ²⁶Hospital de Clínicas I, Asunción, Paraguay, Asuncion del Paraguay, Paraguay, ²⁷Dpto de Reumatología Hospital de Clínicas. Facultad de Ciencias medicas.Universidad Nacional de Asunción, Asuncion del Paraguay, Paraguay, ²⁸Servicio de Reumatologia. Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru, ²⁹Hospital Docente Padre Billini, Santo Domingo, República Dominicana, Santo Domingo, Dominican Republic, ³⁰Clínica Médica C, Hospital de Clínicas, UDELAR, Montevideo, Uruguay, ³¹Hospital Señor del Milagro, Salta, Argentina, ³²Centro de Referencia en Osteoporosis & Reumatología, Cali, Colombia, ³³Hospital General de Agudos Dr. Juan A. Fernández, Buenos Aires, Argentina, CABA, Argentina, ³⁴The University of Alabama at Birmingham, Oakland, CA, ³⁵Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Argentina, ROSARIO, Santa Fe, Argentina
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease with complex multi-systemic involvement. Herpes zoster (HZ) is caused by the reactivation of latent varicella-zoster virus…
Abstract Number: 0237 • ACR Convergence 2024
Tofacitinib: A Retrospective Study on Safety and Adverse Effects
Vrushal Kale¹, Sandeep yadav², Canchi Balakrishnan³, Rohini Samant⁴, Bishakha Swain⁴, Shaurav Khanna⁵, Aashish Agrawal⁵ and Aditi Patankar⁴, ¹P D Hinduja national Hospital and medical Research centre, Mumbai, Maharashtra, India, ²Pd Hinduja hospital, Thane, Maharashtra, India, ³P D Hinduja Hospital and Medical Research Centre, Mahim, Mumbai, Mahin, Maharashtra, India, ⁴P D Hinduja Hospital and Medical Research Centre, Mumbai, mumbai, Maharashtra, India, ⁵P D Hinduja Hospital and Medical Research Centre, Mahim, Mumbai, Mumbai, Maharashtra, India
Background/Purpose: Tofacitinib, an oral Janus kinase inhibitor, is widely used in India to treat rheumatoid arthritis (RA) and other autoimmune diseases. Although its efficacy is…
Abstract Number: 0264 • ACR Convergence 2024
Clinical Value of Metagenomic Next-generation Sequencing in Patients with Connective Tissue Disease Co-infections: A Single-center Study from Southern Hospital in China
Yuan-Yuan Xiao¹, Ai-Ling Lu¹, Han-You Mo², Zhen-Dong He², Jia-Le Wen² and Xuan Yin¹, ¹Guilin Medical University, Guilin, China (People's Republic), ²The First Affiliated Hospital of Guangxi Medical University, Nanning, China (People's Republic)
Background/Purpose: Few studies have been reported on the use of metagenomic next-generation sequencing (mNGS) in patients with connective tissue disease (CTD) co-infections, and more relatively large-scale data…
Abstract Number: 1338 • ACR Convergence 2024
Health Care Utilization and Cost of Herpes Zoster Infection in Patients with Rheumatoid Arthritis, a Retrospective Cohort Study
Mohammad Movahedi¹, Angela Cesta², Xiuying Li², Mark Tatangelo³ and Claire Bombardier³, and OBRI investigators, ¹Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, ²UHN, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada
Background/Purpose: Patients with rheumatoid arthritis (RA) have approximately a twofold increased risk of developing herpes zoster (HZ) compared to the general population. This elevated risk is attributed…
Abstract Number: 2433 • ACR Convergence 2024
Sequential Pneumococcal Vaccination in SLE: Immunogenicity, Side Effects and Comparison with PPSV23 Vaccination
Rudrarpan Chatterjee¹, Sai Yasaswini Kommaraju², Shincy MR³ and Amita Aggarwal⁴, ¹Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow., Lucknow, Uttar Pradesh, India, ²Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, ³Central research lab, Kampewgowda Institute of Medical Sciences, Bengaluru, ⁴Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India
Background/Purpose: SLE patients have increased risk of invasive pneumococcal disease due to immune dysregulation and drugs used in these patients. EULAR 2019 recommendation suggest sequential…
Abstract Number: 0201 • ACR Convergence 2023
Tolerability and Safety of Recombinant Zoster Vaccine in Patients with Inflammatory Rheumatic Musculoskeletal Diseases – A Prospective Longitudinal Study over 12 Months
Ioana Andreica¹, Gianna Chierergo², Stefania Reale², Benjamin Wilde³, Styliani Tsiami⁴, David Kiefer⁴, Philipp Sewerin⁴, Hilal Kavruk⁵, Dimitra Karagkiozidou², Barbara Guminski⁴, Andreas Kribben³, Xenofon Baraliakos⁶, Juergen Braun⁴ and Uta Kiltz⁷, ¹Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ²Rheumazentrum Ruhrgebiet, Herne, and Ruhr-Universität Bochum, Herne, Germany, ³Department of Nephrology, University Hospital Essen, University Duisburg-Essen, Essen, Germany, ⁴Ruhr-Universität Bochum and Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Rheumazentrum Ruhrgebiet, Herne, and Ruhr-Universität Bochum, Düsseldorf, Germany, ⁶Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁷Rheumazentrum Ruhrgebiet, Herne, Germany
Background/Purpose: Herpes zoster (HZ) is common in the elderly, with a lifetime risk of 25%. The primary risk factors for HZ are advanced age and…
Abstract Number: 0415 • ACR Convergence 2023
Serious Infections Hospital Admissions and Mortality in Patients with Early Inflammatory Arthritis: Results from a Large UK Cohort
Maryam Adas¹, Bechman Katie¹, Mark Russell¹, Ioasaf Karafotias¹, Deepak Nagra¹, Sam Norton¹, Mark Garton² and James Galloway¹, ¹King's College London, London, United Kingdom, ²The Shrewsbury and Telford hospital NHS trust, Shropshire, United Kingdom
Background/Purpose: To identify risk of serious infections (SI) according to initial treatment strategy, using conventional synthetic disease modifying anti-rheumatic drugs (csDMARD) and corticosteroids, in patients…
Abstract Number: 1297 • ACR Convergence 2023
COVID-19 Vaccination-related Delayed Adverse Events Among Patients with Rheumatoid Arthritis: Results from the COVAD Study
Mrinalini Dey¹, Bohdana Doskaliuk², Ioannis Parodis³, Julius Lindblom³, Chris Wincup⁴, Mrudula Joshi⁵, Dey Dzifa⁶, Esha Kadam⁷, Parikshit Sen⁸, Samuel Shinjo⁹, Arvind Nune¹⁰, Nelly Ziade¹¹, Yi-Ming Chen¹², Lisa Traboco¹³, CARLOS ENRIQUE TORO GUTIERREZ¹⁴, COVAD Study Group¹⁵, Rohit Aggarwal¹⁶, Vikas Agarwal¹⁷, Latika Gupta¹⁸ and Elena Nikiphorou¹⁹, ¹Queen Elizabeth Hospital, London, United Kingdom; University of Liverpool, Liverpool, United Kingdom, ²SHEI "Ivano-Frankivsk national medical university", Ivano-Frankivsk, Ukraine, ³Karolinska Institutet, Stockholm, Sweden, ⁴King's College Hospital, London, United Kingdom, ⁵Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, ⁶Department of Medicine and Therapeutics, University of Ghana School of Medicine and Dentistry, College of Health Sciences, Korle-Bu, Accra, Ghana, ⁷Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, ⁸Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, ⁹Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, ¹⁰Southport & Ormskirk NHS Foundation Trust, Liverpool, United Kingdom, ¹¹Saint-Joseph University, Beirut, Lebanon, ¹²Taichung Veterans General Hospital, Taichung, Taiwan, ¹³University of the Philippines - Manila, St Luke's Medical Center - Bonifacio Global City, Paranaque, Manila, Philippines, ¹⁴Centro de Estudios de Reumatología y Dermatología SAS, Cali, Colombia, ¹⁵-, -, ¹⁶University of Pittsburgh, Pittsburgh, PA, ¹⁷Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, ¹⁸Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, ¹⁹King's College London, London, United Kingdom
Background/Purpose: COVID-19 vaccines have been proven to be safe in the healthy population. Data on longer-term AEs in people with autoimmune diseases (AIDs), including rheumatoid…
Abstract Number: 1685 • ACR Convergence 2023
SLE Disease Activity Is a More Important Risk Factor Than Immunosuppression for Acquiring Human Papillomavirus (HPV) Infection in Systemic Lupus Erythematosus Patients
Zehra Kazmi¹, Carlos Lorenzo² and Agustin Escalante³, ¹University of Texas Health Science Center at San Antonio, San Antonio, TX, ²UT Heath San Antonio, Shavano Park, TX, ³UT Health Science Center at San Antonio, San Antonio, TX
Background/Purpose: SLE patients have increased rates of HPV infection and cervical cancer. Although some factors are recognized for HPV infection in SLE, the relationship with…
Abstract Number: 2298 • ACR Convergence 2023
SLE Patients Are at High Risk for Tuberculosis Infection: Data from a Lupus Center of an Endemic Country
Victor Leda¹, Andreia Sousa¹, Fernanda Lopes¹, Emily Neves¹, Sandra Pasoto², Danieli Andrade², Michelle Ugolini¹, Eloisa Bonfa², Eduardo Borba¹, Adriana Tonacio¹ and Luciana Seguro¹, ¹Hospital das Clinicas HCFMUSP, University of São Paulo, São Paulo, Brazil, ²University of São Paulo, São Paulo, Brazil
Background/Purpose: SLE patients are at high risk for tuberculosis (TB) infection especially in endemic countries. Despite the importance of this infection condition, there are still…
Abstract Number: 0202 • ACR Convergence 2023
Analysis of the Effects of Immunosuppressive Therapy on Herpes Zoster Events After Each of Three Doses of the BNT162b2 mRNA Vaccine in Patients with Spondyloarthritis (SpA)
Tal Gazitt¹, Noa Hayat², Amir Haddad², Joy Feld³, Nili Stein², Idit Lavi², Ilan Feldhamer⁴, Arnon Dov Cohen⁵, Walid Saliba² and Devy Zisman², ¹Carmel Hospital, Haifa, Israel, ²Carmel Medical Center, Haifa, Israel, ³Carmel and Zvulun Medical Centre, Haifa, Israel, ⁴Chief Physician's Office, Clalit Health Services, Tel Aviv, Israel, ⁵Ben-Gurion University of the Negev, Beer-Sheva, Israel
Background/Purpose: The importance and efficacy of mRNA COVID-19 vaccination in coping with the pandemic are well established, but inconsistencies remain in the data regarding side…
Abstract Number: 0425 • ACR Convergence 2023
Long-term Safety of Rituximab in Rheumatoid Arthritis: A Systematic Review and Meta-analysis
Ioasaf Karafotias, Joshua Rothwell, Maryam Adas, Bechman Katie, Mark Russell, Sam Norton and James Galloway, King's College London, London, United Kingdom
Background/Purpose: Rituximab targets CD20-bearing B cells and is used to treat Rheumatoid Arthritis (RA). Common Variable Immune Deficiency (CVID) is a primary immune deficiency syndrome…
Abstract Number: 1312 • ACR Convergence 2023
Uncovering Risk Factors for Adverse Events and Infections in Rheumatoid Arthritis and Rheumatoid Arthritis with Interstitial Lung Disease Under Biologics or Targeted Synthetic DMARDs: Insights from the KOBIO Registry
Ji-Won Kim¹, Ju-Yang Jung¹, Chang-Hee Suh² and Hyoun-Ah Kim¹, ¹Ajou University School of Medicine, Suwon, South Korea, ²Ajou University Hospital, Suwon, South Korea
Background/Purpose: This study aimed to identify risk factors associated with adverse events (AEs) and infections in patients with rheumatoid arthritis (RA) and comorbid interstitial lung…

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