Abstracts tagged "Infection"

Abstract Number: 2614 • 2018 ACR/ARHP Annual Meeting
The Effect of Secukinumab on the Immunogenicity of Influenza Vaccine in Patients with Psoriatic Arthritis
Ori Elkayam¹, Devy Zisman², Ilana Kaufman³, Uri Arad⁴, Mark Berman⁵, Victoria Furer⁶, Yael Lahat¹, Or Carmi¹, Amir Haddad⁷, Muna Elias⁷, Daphna Paran¹ and Michal Mandelbaum⁸, ¹Department of rheumatology, Tel Aviv medical center and the Sackler Faculty of medicine, Tel Aviv University, Tel Aviv, Israel, ²Technion, Rheumatology Unit Carmel Medical Center, Haifa, Israel, ³Rheumatology, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, ⁴Rheumatology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel, ⁵Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁶Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel, ⁷Rheumatology Unit Carmel Medical Center, Haifa, Israel, ⁸Sheba medical center, Ramat Gan, Israel
Background/Purpose: The humoral response to vaccination may be affected by the use of immunosuppressive drugs. The effect of secukinumab on the humoral response of vaccines…
Abstract Number: 1228 • 2018 ACR/ARHP Annual Meeting
Spine Immobilization and Neurological Complications in Vertebral Osteomyelitis: Results from a Multicenter Prospective Observational Study
Géraldine Bart¹, Guillaume Coiffier², Oriane Merot³, Emmanuel Hoppe⁴, Marion Couderc⁵, Denis Mulleman⁶, Gregoire Cormier⁷, Jean Marc Ziza⁸ and Benoit Le Goff¹, ¹Rheumatology, Nantes University Hospital, Nantes, France, ²Rheumatology, Rennes University Hospital, Rennes, France, ³rheumatology unit, Saint Nazaire Hospital, Saint Nazaire, France, ⁴Angers University Hospital, Angers, France, ⁵Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France, ⁶Université François-Rabelais de Tours, CNRS 7292, Tours, France, ⁷Service de Rhumatologie, CHD de la Roche-Sur-Yon, La Roche-Sur-Yon, France, ⁸Medecine Interne-Rhumatologie, Groupe hospitalier Diaconesses-Croix-Saint-Simon, Paris, France
Background/Purpose: In a previous work, we showed that neurological complication can occur in up to 40% of patients with vertebral osteomyelitis (VO). Bed rest and…
Abstract Number: 2717 • 2018 ACR/ARHP Annual Meeting
Factors Predicting Severe Infections in Patients with Systemic Necrotizing Vasculitides Based on Data from 733 Patients Enrolled in Randomized–Controlled Trials
Lafarge Antoine¹, Christian Pagnoux², Xavier Puéchal³, Maxime Samson⁴, Mohamed Hamidou⁵, Alexandre Karras⁶, Thomas Quémeneur⁷, Matthieu Groh⁸, Luc Mouthon³, Loïc Guillevin³ and Benjamin Terrier⁹, ¹Medecine Interne, National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France, ²Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, ³Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France, ⁴Department of Internal Medicine and Clinical Immunology, François-Mitterrand Teaching Hospital, University of Bourgogne-Franche-Comté, Dijon, France, ⁵Department of Internal Medicine, CHU de Nantes, France, Nantes, France, ⁶Department of Nephrology, Hôpital Européen Georges Pompidou, APHP, Paris, France, Paris, France, ⁷Department of Internal Medicine, CH of Valenciennes, France, Valenciennes, France, ⁸Internal Medicine, Foch, Suresnes, France, ⁹National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France
Background/Purpose: Although overall survival of patients with systemic necrotizing vasculitides (SNVs) has improved markedly over the last 20 years, infectious complications remain a major cause…
Abstract Number: 1071 • 2017 ACR/ARHP Annual Meeting
Increased Susceptibility of SLE-Prone Mice to Pulmonary Haemophilus Influenzae Infection Was Attributed to Dysfunctions of Innate Immune Responses
Wenchao Li and Lingyun Sun, Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China
Background/Purpose: Aside from the disease itself, infections represent the major cause of morbidity and mortality in systemic lupus erythematosus (SLE) patients. Although the daily usage…
Abstract Number: 2841 • 2017 ACR/ARHP Annual Meeting
Infection Is the Major Trigger of Adult Hemophagocytic Syndrome, an Orphan Systemic Hyperinflammatory, Life-Threatening Disease: Analysis in 147 Patients (GEAS-SEMI Registry)
Pilar Brito-Zerón¹, Alejandra Flores-Chavez^2,3,4, Pedro Moral Moral⁵, A. Martínez-Zapico⁶, Pilar Hernández-Jimenez⁷, Guadalupe Fraile Rodriguez⁸, Patricia Perez Guerrero⁹, Eva Fonseca¹⁰, Angel Robles¹¹, María Vaquero Herrero¹², Angela Ruiz de Temiño de la Peña¹³, Maria José Forner¹⁴, José Ramón Larrañaga¹⁵, Mónica Rodriguez Carballeira¹⁶, Luis Fernando Viejo Llorente¹⁷, Manuel Ruiz Muñoz¹⁸, Roberto Hurtado¹⁹, César Morcillo²⁰, Soledad Retamozo²¹ and Manuel Ramos-Casals^22,23, ¹Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Barcelona, Spain, ²Department of Autoimmune Diseases, ICMiD, Hospital Clínic Barcelona, Spain., Barcelona, Spain, ³Programa de Doctorado en Ciencias Médicas, Centro Universitario de Investigaciones Biomédicas (CUIB), Universidad de Colima, Colima, Mexico, Mexico, Mexico, ⁴Unidad de Investigación Biomédica 02 (Unidad de Investigación en Epidemiología Clínica), UMAE, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Jalisco, Mexico, ⁵Hospital La Fé Valencia, Valencia, Spain, ⁶Hospital Universitario de Asturias, Oviedo, Oviedo, Spain, ⁷Internal Medicine, Hospital 12 de Octubre, Madrid, Spain, ⁸Internal Medicine, Hospital Ramón y Cajal, Madrid, Madrid, Spain, ⁹Department of Internal Medicine, Hospital Universitario Puerta del Mar, Cádiz, Cadiz, Spain, ¹⁰Internal Medicine, Hospital de Cabueñes, Gijón, Gijón, Spain, ¹¹Internal Medicine, Hospital La Paz, Madrid, Madrid, Spain, ¹²Complejo Asistencial Universitario de Salamanca, Salamanca, Spain, ¹³Hospital Rio Hortega Valladolid, Valladolid, Spain, ¹⁴Department of Internal Medicine, Hospital Clínico de Valencia, Valencia, Spain, ¹⁵Department of Internal Medicine, Hospital Xeral, Vigo, Vigo, Spain, ¹⁶Hospital Mutua de Terrasa, Terrasa, Spain, ¹⁷Hospital Virgen de la Salud Toledo, Toledo, Spain, ¹⁸Department of Internal Medicine, Hospital Universitario Fundacion Alcorcón, Madrid, Spain, ¹⁹Hospital Vega Baja de Orihuela, Alicante, Spain, ²⁰Department of Medicine, Hospital CIMA-Sanitas, Barcelona, Barcelona, Spain, ²¹Rheumatology Unit, Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba, Argentina, ²²Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Spain, Barcelona, Spain, ²³Department of Medicine, University of Barcelona, Barcelona, Spain., Barcelona, Spain
Background/Purpose: Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is an increasingly-recognized condition in adults, characterized by a wide range of etiologies, symptoms and outcomes, but with…
Abstract Number: 1440 • 2017 ACR/ARHP Annual Meeting
The Effectiveness of Zoster Vaccine in RA Patients Subsequently Treated with Tofacitinib
Kevin Winthrop¹, Ann Wouters², Ernest Choy³, Chudy Nduaka⁴, Pinaki Biswas², Lisy Wang⁵, Jennifer Hodge², Irina Lazariciu⁶, Koshika Soma⁵, Christopher F Mojcik², Elie Needle⁷ and William F C Rigby⁸, ¹Oregon Health & Science University, Portland, OR, ²Pfizer Inc, New York, NY, ³CREATE Center, Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom, ⁴Pfizer Inc, Collegeville, PA, ⁵Pfizer Inc, Groton, CT, ⁶QuintilesIMS, Saint-Laurent, QC, Canada, ⁷Pfizer Inc, Pearl River, NY, ⁸Geisel School of Medicine at Dartmouth, Lebanon, NH
Background/Purpose: RA patients (pts) are at increased risk of herpes zoster (HZ), and ACR guidelines recommend vaccination in pts aged ≥50 years prior to starting…
Abstract Number: 2842 • 2017 ACR/ARHP Annual Meeting
Usefulness of Polymerase Chain Reaction for Diagnosing Whipple’S Disease in Rheumatology
Marion Herbette¹, Jean Baptiste Cren², Laurie Joffres³, charlotte lucas⁴, Emilie Ricard⁵, Carine Salliot⁶, Jerome Guinard⁷, Aleth Perdriger⁸, Elisabeth Solau-Gervais⁹, Béatrice Bouvard¹⁰ and Alain Saraux¹¹, ¹Rheumatology, University Hospital, Brest, France, ²Rheumatology, University Hospital of Angers, Angers, France, ³University Hospital de Poitiers, Poitiers, France, ⁴Rheumatology, University Hospital, Rennes, France, ⁵Rheumatology, University Hospital, Orléans, France, ⁶department of Rheumatology, Orleans, France, ⁷Microbiology, CHU Angers, Angers, France, ⁸Service de Rhumatologie, CHRU de Rennes, Rennes, France, ⁹Rhumatologie, University Hospital, Poitiers, France, ¹⁰rheumatology, CHU Angers, Angers, France, ¹¹Rheumatology, Brest University Medical School Hospital, Brest, France
Background/Purpose: Whipple's disease should be considered in patients with recurrent episodes of seronegative arthritis in the large limb, various symptoms (fever, uveitis,...) or biological abnormalities…
Abstract Number: 1457 • 2017 ACR/ARHP Annual Meeting
Perioperative Management of Methotrexate and Tumor Necrosis Factor Inhibitor Combination Therapy in Rheumatoid Arthritis Patients
Hsin-Hsuan Juo^1,2 and Bernard Ng^1,3, ¹rheumatology, University of Washington, seattle, WA, ²rheumatology, VA Puget Sound Health Care System, seattle, WA, ³Rheumatology, VA Puget Sound Health Care System, seattle, WA
Background/Purpose: Rheumatoid arthritis (RA) patients have a higher frequency of requiring surgical procedures and worse surgical outcome. However, literature regarding post-surgical infectious outcome associated with…
Abstract Number: 1587 • 2017 ACR/ARHP Annual Meeting
Mycobacterial Infection in Systemic Lupus Erythematosus: Clinical Significance and Associated Factors. Data from the Registry of Patients with SLE of the Spanish Society of Rheumatology (RELESSER)
Ana Lois-Iglesias¹, Víctor del Campo-Pérez², Iñigo Rúa-Figueroa³, Coral Mouriño-Rodriguez⁴, Francisco Javier López Longo⁵, María Galindo⁶, Jaime Calvo-Alen⁷, Jesús Ibañez Ruán⁸, Alejandro Olivé⁹, Rafael-Benito Melero González⁴, Antonio Fernandez-Nebro¹⁰, José Antonio Bernal¹¹, Celia Erausquin¹², Eva Tomero¹³, Maria Loreto Horcada¹⁴, Esther Uriarte¹⁵, Mercedes Freire¹⁶, Carlos Alberto Montilla-Morales¹⁷, Ana Sánchez Atrio¹⁸, Alina Boteanu¹⁹, Elvira Diez Alvarez²⁰, Javier Narváez²¹, Víctor Martínez Taboada²², Lucía Silva Fernández²³, Esther Ruiz Lucea²⁴, Jose Luis Andreu²⁵, José Hernández Beiraín²⁶, Marian Gantes²⁷, Blanca Hernández-Cruz²⁸, Jose Javier Perez Venegas²⁹, Ángela Pecondón Español³⁰, Nuria Lozano-Rivas³¹, Monica Ibanez Barcelo³², Gema Bonilla³³, Vicente Torrente³⁴, Ivan Castellví³⁵, Juan José Alegre³⁶, Mireia Moreno³⁷, José Luis Marenco de la Fuente³⁸, Cesar Magro-Checa³⁹, Tomás Vázquez Rodríguez⁴⁰, Victor Quevedo⁴¹, Patricia Richi⁴², Maria Teresa Oton Sanchez⁴³ and JM Pego-Reigosa⁴⁴, ¹Rheumatology, University Hospital A Coruña, A Coruña, Spain, ²Preventive Medicine and Epidemiology, EOXI Vigo, Vigo, Spain, ³Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, ⁴Rheumatology, EOXI Vigo, Vigo, Spain, ⁵Rheumatology, Hospital Gregorio Marañón, Madrid, Spain, ⁶Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, ⁷Rheumatology, Txagorritxu Hospital, Araba, Vitoria, Vitoria, Spain, ⁸POVISA, Rheumatology, Vigo, Spain, ⁹Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, ¹⁰Rheumatology, Regional Universitary Hospital of Málaga, Malaga, Spain, ¹¹Reumatología, Hospital Universitario del Vinalopó, Elche, Spain, ¹²Rheumatology, Hospital de Gran Canaria Dr Negrin, Las Palmas GC, Spain, ¹³Hospital La Princesa. Madrid., Madrid, Spain, ¹⁴Rheumatology, Complejo Hospitalario de Navarra, Pamplona, Spain, ¹⁵Reumatología, Hospital de Donosti, Donosti, Spain, ¹⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo HospitalarioUniversitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ¹⁷Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ¹⁸University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology Department, Alcalá de Henares, Madrid, Spain, ¹⁹University Hospital Ramón y Cajal, Madrid, Spain, ²⁰Complejo Asistencial Universitario de León. León. Spain, León, Spain, ²¹Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain, ²²Rheumatology, Hospital Marqués de Valdecilla, Santander, Spain, ²³Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ²⁴Hospital de Basurto, Bilbao, Spain, ²⁵Rheumatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, ²⁶Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, ²⁷Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, ²⁸Rheumatology, Hospital Universitario Virgen Macarena, Sevilla, Spain, ²⁹Rheumatology, Hospital de Jerez de la Frontera, Jerez de la Frontera, Spain, ³⁰Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, ³¹Rheumatology, Hospital Virgen de la Arrixaca, murcia, Spain, ³²H. Son Llatzer, Palma de Mallorca, Spain, ³³Hospital Universitario La Paz, Madrid, Spain, ³⁴Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain, ³⁵Rheumatology, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain, ³⁶Sección de Reumatología Hospital Universitario Dr Peset Valencia, Valencia, Spain, ³⁷Rheumatology, Hospital Universitari Parc Taulí, Sabadell, Spain, ³⁸Rheumatology, Hospital de Valme, Seville, Spain, ³⁹Department of Rheumatology, Leiden University Medical Center, Leiden, Spain, ⁴⁰Rheumatology, Hospital Lucus Augusti, Lugo, Spain, ⁴¹Rheumatology, Hospital de Monforte, Lugo, Spain, ⁴²Hospital Infanta Sofía, Madrid, Spain, ⁴³Rheumatology Department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain, ⁴⁴Rheumatology Section, Hospital de Meixoeiro, Pontevedra, Spain, Vigo, Spain
Background/Purpose: The aim of this work is to study the prevalence of mycobacterial infection (M.I.), the associated factors and their clinical significance in patients included…
Abstract Number: 1967 • 2017 ACR/ARHP Annual Meeting
Strongyloides Screening in Immunocompromised Immigrant Rheumatology Patients
Sahitya Mallipeddi¹, Christina Coyle² and Beverly Johnson¹, ¹Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ²Infectious Diseases, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Strongyloides Stercoralis is a helminthic infection that is usually chronic and asymptomatic and may persist undiagnosed for decades. Patients from strongyloides endemic areas (tropics…
Abstract Number: 1972 • 2017 ACR/ARHP Annual Meeting
Causes of Death in 350 Patients with Systemic Autoimmune Rheumatic Diseases
Juan Gabriel Ovalles-Bonilla^1,2, Olaia Fernández-Berrizbeitia³, Julia Martínez-Barrio¹, Larissa Valor¹, Diana Hernández¹, Iustina Janta¹, Belen Serrano¹, Claudia Saez¹, Roberto Gonzalez¹, María Correyero¹, Leticia García¹, Ana López-Cerón¹, Alicia Silva¹, Juan Carlos Nieto¹, Carlos González^1,4, Indalecio Monteagudo¹ and Francisco Javier López Longo^1,4, ¹Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ²Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain, ³Rheumatology, Hospital Universitario Basurto, Bilbao, Spain, ⁴Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain
Background/Purpose: The major SARD have an increased mortality compared to the general population. It is well known that the main causes of death in Systemic…
Abstract Number: 2082 • 2017 ACR/ARHP Annual Meeting
Clinical Presentation, Management, and Prognosis of Pseudogout in Prosthetic Joint Implant Patients: A Retrospective Study
Merit P. George¹, Floranne C. Ernste², Aaron J. Tande³, Douglas R. Osmon³, Tad M. Mabry⁴ and Elie F. Berbari³, ¹Mayo Clinic School of Medicine, Rochester, MN, ²Division of Rheumatology, Mayo Clinic Rochester, Rochester, MN, ³Division of Infectious Diseases, Mayo Clinic Rochester, Rochester, MN, ⁴Division of Orthopedic Surgery, Mayo Clinic Rochester, Rochester, MN
Background/Purpose: The prevalence of total knee arthroplasty (TKA) and total hip arthroplasty (THA) has risen considerably in the U.S. There has been a relative lack…
Abstract Number: 271 • 2017 ACR/ARHP Annual Meeting
The Trend of Incidence Rate, Frequency and HLA Phenotype of Reactive Arthritis and Uveitis in Japanese Patients with Bladder Cancer Following Intravesical BCG Therapy: A 20-Year, Two-Center Retrospective Study
Yoshinori Taniguchi¹, Satoshi Inotani², Hirofumi Nishikawa², Kosuke Inoue³, Taro Horino², Takashi Karashima⁴, Yasuhiko Yoshinaga⁵ and Yoshio Terada³, ¹Endocrinology, Metabolism,Nephrology and Rheumatology, Kochi University, Kochi, Japan, ²Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi Medical School, Nankoku, Japan, ³Kochi University, Nankoku, Japan, ⁴Urology, Kochi University, Nankoku, Japan, ⁵Kurashiki Medical Center, Kurashiki, Japan
Background/Purpose: Intravesical instillation of Bacillus Calmette-Guerin (iBCG) is used as an effective immunotherapy of bladder cancer. However it may have, as adverse event, a reactive…
Abstract Number: 2140 • 2017 ACR/ARHP Annual Meeting
Infections and Medications Associated with Onset of Myositis in Myovision, a National Myositis Patient Registry
Lisa G Rider¹, Payam Noroozi Farhadi¹, Nastaran Bayat¹, Jesse Wilkerson², Abdullah Faiq¹, John McGrath², Hermine I. Brunner³, Bob Goldberg⁴ and Frederick W Miller¹, ¹Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, ²Social and Scientific Systems, Inc., Durham, NC, ³Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴The Myositis Association, Alexandria, VA
Background/Purpose: Myositis is a rare systemic autoimmune disease with suspected environmental and genetic risk factors, but little is known about specific infections and medications that…
Abstract Number: 276 • 2017 ACR/ARHP Annual Meeting
Follow-up of Patients with Musculoskeletal Manifestations Related to Chikungunya Fever
Paula Murari-Nascimento¹, Ana Beatriz Vargas-Santos², Natalia Fortes¹, Heruza Zogbi³, Otília Santos³, Patricia Brasil³, Guilherme Calvet³, Rogério Valls³, Carlos Andrade³, Andre Siqueira³, Geraldo Castelar-Pinheiro², Letícia Pereira¹ and Rodrigo B. Chaves-Amorim⁴, ¹State University of Rio de Janeiro, Rio de Janeiro, Brazil, ²Internal Medicine - Rheumatology, State University of Rio de Janeiro, Rio de Janeiro, Brazil, ³Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation – FIOCRUZ, Rio de Janeiro, Brazil, ⁴Universidade do Estado do Rio de Janeiro - UERJ, Rio de Janeiro, Brazil
Background/Purpose: Chikungunya fever (CHIK) has joint involvement as a striking characteristic, which may persist for months. This study aimed to better understand the clinical impact of…

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