Abstracts tagged "Infection"

Abstract Number: 0256 • ACR Convergence 2024
Anti-TNF Therapy as a Potential Risk of Leishmania Infections
Gloria Albaladejo Paredes¹, Alicia Pérez González¹, Esther Monleón Acosta¹, Jose Andrés Rodríguez Fernández¹, Pedro José Manuel Hernández¹, Carlos Fernández Díaz¹, María Rosario Oliva Ruíz¹, Jose María Andreu Ubero², Paloma Valentina Castillo Dayer², Edgar Soriano Navarro³, David Pérez Parra⁴, Claudia Alejandra Capozzi², María Rocío González Molina⁵, José Francisco Orts Paco⁶, José Pablo Serrano Serra⁶ and Vicente Cogolludo Campillo², ¹Hospital Universitario Santa Lucía, CARTAGENA, Spain, ²Hospital Universitario Santa Lucía, Cartagena, Murcia, Spain, ³Hospital Universitario Santa Lucía, Murcia, Murcia, Spain, ⁴Hospital Universitario Santa Lucía, Murcia, ⁵Hospital Reina Sofía, Murcia, Murcia, Spain, ⁶Hospital Universitario Reina Sofía, Murcia, Murcia, Spain
Background/Purpose: Leishmaniasis is an infectious disease caused by protozoon that occurs endemically in the Mediterranean Basin and South America and can affects to travellers to…
Abstract Number: 0844 • ACR Convergence 2024
Effectiveness and Safety of the Recombinant Zoster Vaccine in Patients ≥18 Years of Age with Systemic Lupus Erythematosus or Multiple Sclerosis
Sheryl Kluberg¹, Sophie E. Mayer², O’Mareen Spence³, Driss Oraichi⁴, Harry Seifert⁴, Omar Ali³, Huifeng Yun⁴, Andrew L. Simon⁵, Jenice S. Ko⁶, Caroline Hugh⁷, Meg Her⁷, Kathleen Shattuck⁷, Richard Platt⁸, Aziza Jamal-Allial⁹, Djeneba Audrey DJIBO¹⁰, Kimberly Daniels¹¹, Qianli Ma¹², Cheryl N McMahill-Walraven¹⁰, Rachel P. Ogilvie¹³, Kristin Palmsten¹⁴, Mano Selvan¹⁵, Najat Ziyadeh¹⁶, Alexis Ogdie¹⁷ and Michael George¹⁸, ¹Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, ²Harvard Pilgrim Health Care Institute, Durham, ³GSK, Rockville, ⁴GSK, Rockville, MD, ⁵Harvard Pilgrim Healthcare Institute, Boston, MA, ⁶Harvard Pilgrim Health Care Ins􀆟tute, Boston, MA, ⁷Harvard Pilgrim Health Care Institute, Boston, MA, ⁸Harvard Pilgrim Health Care Institute / Harvard Medical School, Boston, MA, ⁹Carelon Research, Elevance Health, Newton, ¹⁰CVS Health, Blue Bell, ¹¹Carelon Research, Elevance Health, Wilmington, ¹²Humana Healthcare Research, Inc., Louisville, ¹³Optum, Boston, MA, ¹⁴HealthPartners Institute, Minneapolis, ¹⁵Humana Healthcare Research, Sugar Land, Texas, ¹⁶Optum, Baltimore, MD, ¹⁷Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ¹⁸University of Pennsylvania, Philadelphia, PA
Background/Purpose: The recombinant zoster vaccine (RZV) is US Food and Drug Administration-approved for the prevention of herpes zoster (HZ, shingles) in adults ≥50 years, and…
Abstract Number: 1888 • ACR Convergence 2024
Anti-Spike Antibodies Protect Against COVID-19 Infection in Immune-Mediated Inflammatory Diseases: Findings from the SUCCEED Study
Jeremiah Tan¹, J. Antonio Avina-Zubieta², Paul Fortin³, Anne-Claude Gingras⁴, Maggie Larche⁵, Dawn Bowdish⁵, Claudie Berger⁶, Ines Colmegna⁷, Carol Hitchon⁸, Diane Lacaille², Dawn Richards⁹, Nadine Lalonde¹⁰, Ayesha Kirmani¹, Jennifer Lee¹¹ and Sasha Bernatsky⁶, ¹Arthritis Research Canada, Vancouver, BC, Canada, ²Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada, ³Centre ARThrite - CHU de Québec - Université Laval, Quebec, QC, Canada, ⁴Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada, ⁵McMaster University, Hamilton, ON, Canada, ⁶Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁷The Research Institute of the McGill University Health Centre, Montréal, QC, Canada, ⁸University of Manitoba, Winnipeg, MB, Canada, ⁹Canadian Arthritis Patients Alliance, Toronto, ON, Canada, ¹⁰COVID-19 Global Rheumatology Alliance, London, ON, Canada, ¹¹The Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: People with immune-mediated inflammatory diseases (IMIDs) may be more vulnerable to severe COVID-19 outcomes. COVID-19 vaccination is a key element in mitigating this risk.…
Abstract Number: 0257 • ACR Convergence 2024
High Prevalence of Strongyloides Antibodies in Patients at Risk for Dissemination. A Call for Action
Jaspreet Bhatti¹, Kyu-In Lee¹, Arushika Yedla¹, Julia Ash¹, James Miceli¹, Kirk Sperber¹ and Amy Wasserman², ¹Westchester Medical Center, Valhalla, NY, ²Westchester Medical Center, Valhalla
Background/Purpose: Strongyloides Stercoralis is a human intestinal nematode widely found in tropical and subtropical regions that frequently causes chronic and asymptomatic infection (Table 1). Immunosuppression in a host…
Abstract Number: 0898 • ACR Convergence 2024
A Blood Transcriptome Signature Distinguishes Between Diverse Systemic Autoimmune Diseases and Infection
Kleio-Maria Verrou¹, Argyrios Theophilopoulos², Nikolaos Vlachogiannis³, George Kollias⁴, Christoforos Nikolaou⁵ and Petros Sfikakis¹, ¹Joint Academic Rheumatology Program, School of Medicine, National and Kapodistrian University of Athens. Centre of New Biotechnologies and Precision Medicine (CNBPM), School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, Athens, Greece, ²Department of Immunology, Scripps Clinic and Research Foundation, San Diego, CA, ³Joint Academic Rheumatology Program, School of Medicine, National and Kapodistrian University of Athens. Centre of New Biotechnologies and Precision Medicine (CNBPM), School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, Zografou, Greece, ⁴Centre of New Biotechnologies and Precision Medicine (CNBPM), School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. Institute for Bioinnovation, Biomedical Sciences Research Center “Alexander Fleming”, Vari, Greece. Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece, Athens, Greece, ⁵Institute for Bioinnovation, Biomedical Sciences Research Center “Alexander Fleming”, Athens, Greece
Background/Purpose: The most pathogenic responses against self and foreign antigens that lead to systemic autoimmune diseases and infections, respectively, overall engage similar immunologic components. Consequently, there are…
Abstract Number: 1897 • ACR Convergence 2024
People Living with Autoimmune Disease Are at Higher Risk of Suffering from Post-Acute Sequelae of SARS-CoV-2 but Immunization Is Protective
Shahdi Malakooti¹, Marc Abboud², Jennifer Murphy³, Nora Singer⁴ and Grace McComsey⁵, ¹MetroHealth at Case Western Reserve University, Cleveland, ²Saint Joseph Medical School, Beirut, Lebanon, ³University Hospitals, Cleveland, OH, ⁴MetroHealth System at Case Western Reserve University School of Medicine, Cleveland, OH, ⁵University Hospitals at Case Western Reserve University, Cleveland
Background/Purpose: Post-Acute Sequelae of SARS-CoV-2 (PASC) include new or worsening of existing symptoms 3 months or more after SARS-CoV-2 infection. We have shown that vaccination…
Abstract Number: 0132 • ACR Convergence 2024
Patients with Systemic Autoimmune Rheumatic Diseases Remain at Risk for Hospitalization for COVID-19 Infection in the Omicron Era (2022-2024): A Retrospective Cohort Study
Naomi Patel¹, Andrew King¹, Shruthi Srivatsan¹, Xiaosong Wang², Emily Kowalski³, Kathleen Vanni³, Grace Qian², Jennifer Hanberg³, Katarina Bade³, Alene Saavedra³, Kevin Mueller³, Zachary Williams¹, Colebrook Johnson¹, Madison Negron¹, Jeffrey Sparks⁴ and Zachary Wallace⁵, ¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women’s Hospital, Boston, MA, ³Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA, ⁵Massachusetts General Hospital, Newton, MA
Background/Purpose: The risk of severe acute COVID-19 infection has substantially decreased since the start of the pandemic. However, the risk of severe acute COVID-19 outcomes…
Abstract Number: 0259 • ACR Convergence 2024
Whipple’s Disease in Patients Initially Diagnosed with Rheumatic Diseases: A Case Series
Judith den Hertog¹, Maike Wientjes¹, Jaap ten Oever², Merel Opdam¹, Denise Telgt¹ and Alfons den Broeder¹, ¹Sint Maartenskliniek, Ubbergen, Netherlands, ²Radboudumc, Nijmegen, Netherlands
Background/Purpose: Whipple’s disease is a presumably rare, chronic infectious disease caused by the bacterium Tropheryma whipplei. Symptoms include weight loss, diarrhea, abdominal discomfort, joint pain…
Abstract Number: 0984 • ACR Convergence 2024
Predicting Risk of Infection in Hospitalized Patients with Rheumatic Diseases from the MIMIC-IV Clinical Database: A Machine Learning Approach
Mario Felix¹ and Lais Osmani², ¹Yale, Hamden, CT, ²Yale, New Haven, CT
Background/Purpose: Rheumatic diseases often require immunosuppressive treatment, increasing the risk of infection. Clinicians frequently face challenges distinguishing between infection and disease flare in these patients,…
Abstract Number: 1938 • ACR Convergence 2024
Evaluating Diagnostic Performance of Mycobacterium Tuberculosis Derived Cell-free DNA (CF-DNA) for Diagnosis of Osteoarticular Tuberculosis (OATB): A Novel Method
Kusum Sharma¹, Aman Sharma², Mandeep Singh Dhillon³ and Salony Verma⁴, ¹PGIMER, Chandigarh, Chandigarh, India, ²PGIMER, Chandigarh, India, Chandigarh, Chandigarh, India, ³Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, Chandigarh, India, ⁴Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India
Background/Purpose: Diagnostic delay not only worsens the outcomes of tuberculosis but also important impediments to TB elimination efforts. The DNA present in cell-free form is…
Abstract Number: 0138 • ACR Convergence 2024
SARS-CoV-2 Vaccine Acceptance, Hesitancy and Uptake in a Cohort of Patients with Inflammatory Rheumatic Diseases (IRD)
iulia roman¹, Xenofon Baraliakos², Uta Kiltz³, Juergen Braun⁴ and Ioana Andreica⁵, ¹Rheumazentrum Ruhrgebiet, Herne, Germany, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, ⁴Rheuma Praxis, Ruhr-University Bochum, Berlin, Germany, ⁵Rheumazentrum Ruhrgebiet Herne, Herne, Germany
Background/Purpose: Vaccine acceptance is important to achieve high vaccination coverage and possibly herd immunity. Related to the evolution of the SARS-CoV-2 pandemic with its socio-political…
Abstract Number: 0260 • ACR Convergence 2024
National Survey on Patient’s Knowledge and Drivers of Human Papillomavirus (HPV) Vaccination in Immune-mediated Inflammatory Diseases (IMIDs)
Tiphaine Goulenok¹, Arthur Mageau², Chrystelle Francois¹, Eric HACHULLA³, Thomas Papo² and Karim Sacré², ¹Assistance Publique Hôpitaux de Paris, Paris, France, ²Université Paris Cité, Paris, France, ³CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Auto-immunes Systémiques Rares du Nord et Nord-Ouest de France (CeRAINO), Lille, France., LILLE, France
Background/Purpose: Persistent human papillomavirus (HPV) infection is the cause of cervical cancer. Patients with immune-mediated inflammatory diseases (IMIDs) exposed to immunosuppressive therapy are at increased risk…
Abstract Number: 0990 • ACR Convergence 2024
Predictors of Adverse Events and Complications in Cirrhotic Patients with Rheumatoid Arthritis: A Nationwide Analysis
Nidaa Rasheed¹, Humzah Iqbal² and Candice Reyes³, ¹UCSF Fresno, Fresno, CA, ²UCSF FRESNO, FRESNO, ³VACCHCS, Fresno, CA
Background/Purpose: Cirrhosis is associated with a host of complications such as coagulopathy, renal impairment, esophageal varices, peritonitis, and increased mortality. Rheumatoid arthritis (RA) is a…
Abstract Number: 2209 • ACR Convergence 2024
Impact of Common Infections on Medication Interruptions, Quality of Life, and Disease Flares in Patients with Rheumatoid Arthritis
Michael George¹, Kelly Gavigan², Shilpa Venkatachalam³, David Curtis², Laura Stradford⁴, William Benjamin Nowell⁵, Joshua Baker¹, Fenglong Xie⁶ and Jeffrey Curtis⁷, ¹University of Pennsylvania, Philadelphia, PA, ²Global Healthy Living Foundation, Upper Nyack, NY, ³Global Healthy Living Foundation, New York, NY, ⁴Global Healthy Living Foundation, Nyack, NY, ⁵Regeneron, New York, NY, ⁶University of Alabama at Birmingham, Birmingham, AL, ⁷University of Alabama at Birmingham, Hoover, AL
Background/Purpose: Serious infections are a major cause of morbidity and mortality in patients with RA, but less is known about more common, non-serious infections. We…
Abstract Number: 0142 • ACR Convergence 2024
The Impact of Hospital Region on Mortality and Other Outcomes in Patients with Gout: A Two-Year Nationwide Analysis
Nidaa Rasheed¹, kHALED ABDULLAH² and Candice Reyes³, ¹UCSF Fresno, Fresno, CA, ²UCSF FRESNO, FRESNO, ³VACCHCS, Fresno, CA
Background/Purpose: Gout is characterized by chronic inflammatory arthritis caused by the deposition of monosodium urate crystals and leads to increased risk of complications, such as…

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