Abstracts tagged "immunosuppressants"

Abstract Number: 1802 • 2016 ACR/ARHP Annual Meeting
Prevalence of CMV in the Ohio State University Lupus Population
Brian LaMoreaux¹, Alexa Meara², Holly Steigelman³, Juliette Yedimenko⁴, Wael N. Jarjour⁵ and Stacy P. Ardoin⁶, ¹Rheumatology, Fellow, Columbus, OH, ²Internal Medicine/Rheumatology, The Ohio State University, Columbus, OH, ³The Ohio State University, Columbus, OH, ⁴S2056, The Ohio State University, Columbus, OH, ⁵Department of Rheumatology/Medicine, Ohio State University, Columbus, OH, ⁶Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH
Background/Purpose: Systemic Lupus Erythematous (SLE) is a clinically variable autoimmune disease occurring predominantly in women of childbearing age. SLE treatment can range from close clinical…
Abstract Number: 2805 • 2016 ACR/ARHP Annual Meeting
Outcomes of Lupus Nephritis Patients Following Discontinuation of Treatment
Chee Ken Cheah¹, Shirish Sangle (Joint First Author)¹, Alina Casian², Oier Barrutia¹, Munther Khamashta¹ and David D'Cruz¹, ¹Louise Coote Lupus Unit, Guy's and St. Thomas' Hospital, London, United Kingdom, ²Rheumatology, Louise Coote Lupus Unit, Guy's and St. Thomas' Hospital, London, United Kingdom
Background/Purpose: Lupus nephritis (LN) complicates 60% of systemic lupus erythematosus (SLE) patients within 5 years of diagnosis. Glucocorticoids and disease modifying immunosuppressive drugs (IS) are…
Abstract Number: 283 • 2015 ACR/ARHP Annual Meeting
Altered Serum Fatty Acid Profiles in Patients with Polymyositis or Dermatomyositis Compared to Healthy Individuals and in Relation to Immunosuppressive Treatment
Joan Raouf¹, Helena Idborg¹, Petter Olsson², Per Johan Jakobsson¹, Ingrid E. Lundberg¹ and Marina Korotkova¹, ¹Medicine, Department of Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet S-171 76, Stockholm, Sweden, Stockholm, Sweden, ²Analytical Chemistry, Department of Analytical Chemistry, Stockholm University, Sweden, Stockholm, Sweden
Background/Purpose: Polymyositis (PM) and dermatomyositis (DM) are chronic autoimmune diseases, characterized by muscle fatigue. Despite conventional immunosuppressive treatment including high doses of glucocorticoids, only a…
Abstract Number: 831 • 2015 ACR/ARHP Annual Meeting
Mycophenolate Decreases the Frequency of Endoscopic Therapy for Gastric Antral Vascular Ectasia in Patients with Systemic Sclerosis
Tiffany Lin¹, James Bena², Shannon Morrison² and Soumya Chatterjee³, ¹Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, ²Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, ³Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Gastric antral vascular ectasia (GAVE) is an increasingly recognized cause of upper gastrointestinal bleeding in patients with systemic sclerosis (SSc). These patients may require…
Abstract Number: 923 • 2015 ACR/ARHP Annual Meeting
Perceptions of Infectious Risk of Immunosuppressive Medications Among Treating Physicians
Rebecca Sharim¹, Leny Mathew², Michael George³, Preethi Thomas⁴ and Misha Rosenbach⁵, ¹Rheumatology, Hospital of the University of Pennsylvania, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, ⁴Department of Rheumatology, Hospital of the University of Pennsylvania, Philadelphia, PA, ⁵Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Physicians often encounter patients who are treated with immunosuppressive agents and must consider the risk of infection that the medications may pose. We explored…
Abstract Number: 1397 • 2015 ACR/ARHP Annual Meeting
Successful Treatment of Cardiac Sarcoidosis with Biologic and Immunosuppressive Combination Therapy
Maya Estephan¹, Mehrdad Maz², Mark Hamblin³ and Julian Magadan¹, ¹Division of Allergy, Clinical Immunology, and Rheumatology, University of Kansas Medical Center, Kansas City, KS, ²Division of Rheumatology, University of Kansas Medical Center, Kansas City, KS, ³Pulmonary and Critical Care Medicine, ILD Clinic, University of Kansas Medical Center, Kansas city, KS
Background/Purpose: Although cardiac involvement is symptomatic in only 5% of patients with sarcoidosis, it is considered an important prognostic factor and the second leading cause…
Abstract Number: 1567 • 2015 ACR/ARHP Annual Meeting
Occurrence of Serious Infection in Patients with Rheumatoid Arthritis Treated with Biologics and Denosumab Observed in a Clinical Setting
Matthew Wong-Pack¹, Rod Rodjanapiches¹, Arthur Lau^1,2,3, George Ioannidis^1,3, Sally Wade⁴, Leslie Spangler⁴, Celia JF Lin⁴, Patrick Roy-Gayos¹, William G Bensen^1,3, Robert Bensen³ and Jonathan D Adachi^1,3, ¹McMaster University, Hamilton, ON, Canada, ²Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ³St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ⁴Amgen Inc., Thousand Oaks, CA
Background/Purpose: Previous studies combining immunosuppressive biologics have shown an increased risk of infections. Few studies have examined the risk of infection with concurrent use of…
Abstract Number: 1988 • 2015 ACR/ARHP Annual Meeting
Efficacy and Safety of Mizoribine for Polymyalgia Rheumatica: Analysis of 47 Cases
Ryo Rokutanda¹, Chisun Min², Yuko Kataoka¹, Tokutaro Tsuda¹, Shunya Kaneshita¹, Ken-ichi Yamaguchi³, Koji Takasugi⁴, Masei Suda¹, Akira Takeda³, Yukio Matsui^1,3, Mitsumasa Kishimoto¹ and Masato Okada¹, ¹Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, ²Division of Allergy and Rheumatology, St. Luke's International Hospital, Tokyo, Japan, ³Allergy and Rheumatology, St. Luke's International Hospital, Tokyo, Japan, ⁴Imuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan
Background/Purpose: Polymyalgia rheumatic (PMR) is an inflammatory rheumatic disease characterized by aching and morning stiffness of body, which is seen almost exclusively in adults over…
Abstract Number: 2502 • 2015 ACR/ARHP Annual Meeting
Implementation of New Pneumococcal Vaccination Recommendations in an Academic Rheumatology Clinic
Alison Bays¹, Renuka Nayak², David I. Daikh³, Jinoos Yazdany⁴ and Gabriela Schmajuk⁵, ¹Rheumatology, University of Washington, Seattle, WA, ²Rheumatology, UCSF, San Francisco, CA, ³Rheumatology, UCSF/VA Medical Center, San Francisco, CA, ⁴Rheumatology, UCSF, SF, CA, ⁵San Francisco VA Medical Center, University of California, San Francisco, San Francisco, CA
Background/Purpose: Invasive pneumococcal disease is approximately four times more common among patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) compared to healthy counterparts.…
Abstract Number: 3193 • 2015 ACR/ARHP Annual Meeting
Immunomodulatory and Antiviral Therapies in a Mouse Model of Chikungunya Viral Arthritis
Jonathan Miner¹, Lindsey Cook¹, Raeann Shimak², Julie Fox¹, Alissa Young¹, Kristen Monte², Subhajit Poddar², Michael Diamond¹ and Deborah Lenschow¹, ¹Department of Medicine, Washington University in Saint Louis School of Medicine, Saint Louis, MO, ²Washington University in Saint Louis School of Medicine, Saint Louis, MO
Background/Purpose: Chikungunya virus (CHIKV) is a rapidly emerging arthritogenic mosquito-borne alphavirus that has infected more than 1 million individuals in the Western Hemisphere since 2014. …
Abstract Number: 3262 • 2015 ACR/ARHP Annual Meeting
The Influence of Immunosuppressive Therapy on Microangiopathy in Systemic Sclerosis As Measured with Nailfoldcapillaroscopy
Jessica Meijs¹, B. de Boer¹, Anne Schouffoer^1,2, T. W. J. Huizinga³, Hein Putter⁴ and Jeska K. de Vries-Bouwstra¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Haga Hospital, The Hague, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Medical Statitics and Bioinformatics, professor in medical statistics, Leiden, Netherlands
Background/Purpose: Microangiopathy in systemic sclerosis (SSc), as visualized by nailfold videocapillaroscopy (NVC) is a dynamic and sequential process1. In time, NVC patterns progress from early,…
Abstract Number: 2273 • 2014 ACR/ARHP Annual Meeting
Does a Standardized Multidisciplinary Approach Improve Outcomes for Children with NMDA Receptor Antibody Encephalitis? : A Preliminary Assessment of a Single Center Experience
Mered Parnes¹, Amber Stocco², Trung Nguyen³, Jun Teruya⁴, Jeanine Graf³ and Eyal Muscal⁵, ¹Child Neurology, Baylor College of Medicine, Houston, TX, ²Integris Pediatric Neurology, Oklahoma City, OK, ³Pediatrics-critical care, Baylor College of Medicine, Houston, TX, ⁴Pathology, Baylor College of Medicine, Houston, TX, ⁵Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Houston, TX
Background/Purpose: NMDA receptor antibody encephalitis (NMDAR) is a potentially devastating isolated autoimmune condition affecting children and young adults that was mostly unrecognized prior to 2007.…
Abstract Number: 1765 • 2014 ACR/ARHP Annual Meeting
Comparison of Clinical Characteristics of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis By the Serotype Specificity to Myeloperoxidase and Proteinase-3
Takamasa Murosaki, Takeo Sato, Yoichiro Akiyama, Katsuya Nagatani and Seiji Minota, Division of Rheumatology and Clinical Immunology, Jichi Medical University, Tochigi, Japan
Background/Purpose: To correlate the clinical characteristics of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with myeloperoxidase (MPO)-ANCA and proteinase-3 (PR3)-ANCA, and to detect clinical characteristics of…
Abstract Number: 1671 • 2014 ACR/ARHP Annual Meeting
Renal Relapses Are Common in Lupus Nephritis
Angela Pakozdi¹, Ravindra Rajakariar², Michael Sheaff³ and Dev Pyne¹, ¹Rheumatology, Barts Health NHS Trust, London, United Kingdom, ²Renal Medicine, Barts Health NHS Trust, London, United Kingdom, ³Histopathology, Barts Health NHS Trust, London, United Kingdom
Background/Purpose Renal relapses are part of the natural history of lupus nephritis (LN) and represent a significant challenge not only because they are associated with…
Abstract Number: 1663 • 2014 ACR/ARHP Annual Meeting
Influence of Ethnicity on Efficacy of Current Immunosuppressive Protocols in Proliferative Lupus Nephritis
Angela Pakozdi¹, Ravindra Rajakariar², Michael Sheaff³ and Dev Pyne¹, ¹Rheumatology, Barts Health NHS Trust, London, United Kingdom, ²Renal Medicine, Barts Health NHS Trust, London, United Kingdom, ³Histopathology, Barts Health NHS Trust, London, United Kingdom
Background/Purpose Lupus nephritis (LN) is a major complication of systemic lupus erythematous (SLE) and prevalence is estimated to be 50-60%. Recently, variable responses to induction…

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