Abstracts tagged "immunoregulation and systemic lupus erythematosus (SLE)"

Abstract Number: 2876 • ACR/ARHP Annual Meeting 2016
SLE Serum Impairs NO Production in Huvecs through Induction of eNOS Uncoupling
Jim Oates^1,2, Diane L. Kamen³ and Joy N Jones Buie⁴, ¹Medical Service, Ralph H. Johnson VAMC, Charleston, SC, ²Medicine/Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, ³Department of Medicine, Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ⁴Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC
Background/Purpose: Systemic lupus erythematosus (SLE) induces endothelial cell dysfunction (ECD) that can manifest as glomerulonephritis or atherosclerosis. Lupus-prone mice lacking endothelial nitric oxide synthase (eNOS,…