ACR Meeting Abstracts

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Abstracts tagged "immunology and rheumatoid arthritis (RA)"

  • Abstract Number: 2042 • 2018 ACR/ARHP Annual Meeting

    Immunophenotypic Analysis of Tissue-Resident Memory T Cells in Rheumatoid Arthritis

    Seokchan Hong1, Jae Hyung Jung2, Jung Sun Lee3, Jae Bum Won1, Doo-Ho Lim4, Yong-Gil Kim1, Chang Keun Lee1 and Bin Yoo1, 1Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South), 2Asan Institute for Life Science, Asan Medical Center, Seoul, Korea, Republic of (South), 3Division of Rheumatology, Department of Internal Medicine,, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South), 4Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of (South)

    Immunophenotypic analysis of tissue-resident memory T cells in rheumatoid arthritisSeokchan Hong1 Jae Hyung Jung1,2, Jung Sun Lee1, Jae Bum Won1, Doo-Ho Lim3, Yong-Gil Kim1, Chang-Keun…
  • Abstract Number: 288 • 2017 ACR/ARHP Annual Meeting

    The Rheumatoid Arthritis Susceptibility Gene C5orf30 Is an Immunomodulator in Macrophages

    Emma Dorris1, Karen Creevey1, John Moylett1, Simon Tazzyman2, Munitta Muthana2 and Anthony G. Wilson1, 1UCD School of Medicine and Medical Science, Conway Institute, University College Dublin, Dublin, Ireland, 2University of Sheffield Medical School, Sheffield, United Kingdom

    Background/Purpose: rs26232 in the first intron of C5orf30 has been associated with risk of developing rheumatoid arthritis (RA) and severity of tissue damage. C5orf30 is…
  • Abstract Number: 518 • 2015 ACR/ARHP Annual Meeting

    Antibody Responses to Citrullinated Porphyromonas Gingivalis Peptidylarginine Deiminase: Associations with Disease Risk Factors and Severity in Rheumatoid Arthritis

    Priyanka Vashisht1, Jeffrey Payne2, Geoffrey M. Thiele3, Harlan Sayles4, Fang Yu5, Michael J. Duryee6, Carlos D. Hunter6, Benjamin Wiese1, Anne-Marie Quirke7, Patrick Venables7 and Ted R. Mikuls8, 1Internal Medicine - Rheumatology, University of Nebraska Medical Center, Omaha, NE, 2College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, 3Research Services 151, Omaha VA Medical Center, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE, 5Public Health, University of Nebraska Medical Center, Omaha, NE, 6Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 7Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, 8Medicine, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by autoimmunity to citrullinated proteins. Porphyromonas gingivalis (Pg) has been proposed as an epidemiologic link between RA and periodontitis…
  • Abstract Number: 1941 • 2015 ACR/ARHP Annual Meeting

    Senescent T-Cells Expedite RANKL-Dependent Bone Loss in Rheumatoid Arthritis

    Johannes Fessler1, Rusmir Husic2, Elisabeth Lerchbaum3, Verena Schwetz3, Claudia Stiegler3, Barbara Obermayer-Pietsch3, Winfried B. Graninger4 and Christian Dejaco5, 1Rheumatology and Immunology, Medical University Graz, Graz, Austria, 2Rheumatology, Medical University Graz, Graz, Austria, 3Division of Endocrinology and Metabolism, Medical University Graz, Graz, Austria, 4Internal Medicine/Rheumatology, Medical University Graz, Graz, Austria, 5Department of Rheumatology and Immunology, Medical University Graz, Graz, Austria

    Background/Purpose: To study the influence of senescent CD28-T-cells on systemic osteoporosis in rheumatoid arthritis (RA) and patients with primary osteoporosis. Methods: Prospective, cross-sectional study on…
  • Abstract Number: 2702 • 2015 ACR/ARHP Annual Meeting

    Immunophenotyping of Rheumatoid Arthritis Reveals the Linkage Between HLA-DRB1 Genotype, CXCR4 Expressions on Memory CD4+ T Cells, and Disease Activity

    Yasuo Nagafuchi1, Hirofumi Shoda1, Shuji Sumitomo1, Shinichiro Nakachi1, Rika Kato2, Yumi Tsuchida2, Haruka Tsuchiya2, Keiichi Sakurai2, Norio Hanata2, Shoko Tateishi2, Hiroko Kanda2, Keishi Fujio1 and Kazuhiko Yamamoto1, 1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

    Background/Purpose: The HLA-DRB1 is the strongest genetic risk factor for rheumatoid arthritis (RA). Although this fact suggests a pivotal role for adaptive immunity in RA,…
  • Abstract Number: 1737 • 2014 ACR/ARHP Annual Meeting

    Altered Phenotype and Function of Senescent Regulatory T Cells in Rheumatoid Arthritis

    Johannes Fessler1, Chrsitine Schwarz1, Anja C. Ficjan1, Rusmir Husic2, Evelyne Höller3, Angelika Lackner1, Winfried B. Graninger4 and Christian Dejaco1,5, 1Rheumatology and Immunology, Medical University Graz, Graz, Austria, 2Rheumatology, Medical University Graz, Graz, Austria, 3Endocrinology, Medical University Graz, Graz, Austria, 4Internal medicine/Rheumatology and Immunology, Medical University Graz, Graz, Austria, 5Department of Rheumatology and Immunology, Medical University Graz, Graz A-8036, Austria

    Background/Purpose Immunosenescence accompanied by accumulation of senescent T cells  is a hallmark feature in the pathogenesis of rheumatoid arthritis (RA). Here we characterize a novel senescent…
  • Abstract Number: 995 • 2014 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Patients Have Alterations in Inherently Autoreactive 9G4+ B-Cell Subpopulations in Peripheral Blood

    Rita A. Moura1,2, Maria J. Leandro3, Venkat Reddy1, João E. Fonseca2,4 and Geraldine Cambridge3, 1Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, 2Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 3Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, 4Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon, Portugal

    Background/Purpose B-cells utilizing the VH-region immunoglobulin gene VH4-34 produce natural autoreactive antibodies. The rat monoclonal antibody 9G4 recognizes B-cells with VH4-34-encoded B-cell receptors (9G4+ B-cells)…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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