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Abstracts tagged "immunoglobulin (IG) and microparticles"

  • Abstract Number: 749 • ACR/ARHP Annual Meeting 2015

    Microvesicles Containing Nucleic Acids and Expressing Immunoglobulins and HMGB1 Are Abundant in Patients with Systemic Lupus Erythematosus

    Fariborz Mobarrez1, Håkan Wallén2, Iva Gunnarsson3, Johanna Gustafsson4, Agneta Zickert3, David Pisetsky5,6 and Elisabet Svenungsson4, 1Department of Medicine, Karolinska Institutet, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, 2Division of Cardiovascular Medicine, Karolinska Institutet, Department of Clinical Sciences, Stockholm, Sweden, 3Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, 4Department of Medicine, Karolinska Insitutet, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, 5Medical Research Service, Durham VA Hospital, Durham, NC, 6Department of Medicine, Duke University Medical Center,, Durham, NC

    Background/Purpose: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by immune complexes of antinuclear antibodies. As a source of these antigens, increased levels…

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