Abstracts tagged "immunoglobulin (IG) and microparticles"

Abstract Number: 749 • 2015 ACR/ARHP Annual Meeting
Microvesicles Containing Nucleic Acids and Expressing Immunoglobulins and HMGB1 Are Abundant in Patients with Systemic Lupus Erythematosus
Fariborz Mobarrez¹, Håkan Wallén², Iva Gunnarsson³, Johanna Gustafsson⁴, Agneta Zickert³, David Pisetsky^5,6 and Elisabet Svenungsson⁴, ¹Department of Medicine, Karolinska Institutet, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ²Division of Cardiovascular Medicine, Karolinska Institutet, Department of Clinical Sciences, Stockholm, Sweden, ³Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, ⁴Department of Medicine, Karolinska Insitutet, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁵Medical Research Service, Durham VA Hospital, Durham, NC, ⁶Department of Medicine, Duke University Medical Center,, Durham, NC
Background/Purpose: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by immune complexes of antinuclear antibodies. As a source of these antigens, increased levels…

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