Abstracts tagged "Immunogenetics and treatment"

Abstract Number: 2610 • 2016 ACR/ARHP Annual Meeting
Immunogenicity Assessment of Biologics in Clinical Studies in Chronic Inflammatory Disease: A Systematic Review
Boris Gorovits¹, Daniel Baltrukonis², Indranil Bhattacharya³, Mary A Birchler⁴, Deborah Finco², Daniel Sikema⁴, Michael S Vincent⁵, Sadiq Lula⁶, Lisa Marshall⁷ and Timothy Hickling¹, ¹Pfizer, Andover, MA, ²Pfizer, Groton, CT, ³Clinical Pharmacology, Pfizer, Cambridge, MA, ⁴Clinical Immunology, Glaxo Smith Kline BioPharmaceuticals, Upper Merion, PA, ⁵Inflammation and Immunology Research Unit, Pfizer, Cambridge, MA, ⁶Envision Pharma Group, London, United Kingdom, ⁷Inflammation Global Medical Affairs, Pfizer, Collegeville, PA
Background/Purpose: A portion of patients without clinical response to anti-inflammatory biologics have been shown to develop anti-drug antibodies (ADA).1 ADA prevalence varies widely among biologics,…

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Abstracts tagged "Immunogenetics and treatment"

Immunogenicity Assessment of Biologics in Clinical Studies in Chronic Inflammatory Disease: A Systematic Review