Abstracts tagged "Immune Dysregulation and ankylosing spondylitis (AS)"

Abstract Number: 35 • 2017 ACR/ARHP Annual Meeting
B-Cell Subset Differences in Inflammatory Rheumatic Diseases
Joao Lagoas Gomes^1,2, Dario Ligeiro³, Alice Lima³, Cristina Teixeira³, Alexandre Sepriano^4,5, Sofia Ramiro⁶, Carina Lopes⁷, Tiago Costa⁸, Manuela Costa⁸, Jaime Cunha Branco^1,2 and Fernando Pimentel-Santos^1,2, ¹Rheumatology, Hospital Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal, ²CEDOC, NOVA Medical School, Lisbon, Portugal, ³Centro de Sangue e Transplantação de Lisboa, Instituto Português do Sangue e Transplantação (IPST), I.P, Lisbon, Portugal, ⁴CEDOC, NOVA Medical School, Lisboa, Portugal, ⁵Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁶Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ⁷Hospital de Egas Moniz-CHLO, Lisbon, Portugal, ⁸Rheumatology, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal
Background/Purpose: Targeting humoral immunity has been proved effective in several inflammatory rheumatic diseases (IRD). Though clinical trials have shown some efficacy of B-cell depletion in…

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