Abstracts tagged "imaging techniques"

Abstract Number: 1034 • 2012 ACR/ARHP Annual Meeting
Changing Osteoarthritis Treatment Assessment Paradigms: Subchondral Bone Is a More Responsive Measure of Progression Than the Current Radiographic Standard
Michael A. Bowes¹, Christopher B. Wolstenholme¹, Devan Hopkinson¹, Graham R. Vincent¹ and Philip G. Conaghan², ¹Imorphics Ltd, Manchester, United Kingdom, ²University of Leeds, Leeds, United Kingdom
Background/Purpose: Radiographic joint space width (JSW) assessment, a surrogate for cartilage assessment, is the standard for structure modification trials of osteoarthritis (OA). However the subchondral…
Abstract Number: 1009 • 2012 ACR/ARHP Annual Meeting
A New Approach for Detecting Progressive Joint Damage Using 3D Imaging From High-Resolution Peripheral Quantitative Computed Tomography: Measuring Reproducibility
Cheryl Barnabe¹, Helen R. Buie², Michelle Kan², Susan G. Barr³, Liam Martin³ and Steven K. Boyd², ¹Medicine, Community Health Sciences, University of Calgary, Calgary, AB, Canada, ²Mechanical Engineering, University of Calgary, Calgary, AB, Canada, ³Medicine, University of Calgary, Calgary, AB, Canada
A New Approach for Detecting Progressive Joint Damage using 3D Imaging from High-Resolution Peripheral Quantitative Computed Tomography: Measuring Reproducibility Background/Purpose: Joint space narrowing is an…
Abstract Number: 732 • 2012 ACR/ARHP Annual Meeting
Changes in Subchondral Bone Provide a Sensitive Marker for Osteoarthritis and Its Progression: Results From a Large Osteoarthritis Initiative Cohort
Michael A. Bowes¹, Christopher B. Wolstenholme¹, Devan Hopkinson¹, Graham R. Vincent¹ and Philip G. Conaghan², ¹Imorphics Ltd, Manchester, United Kingdom, ²University of Leeds, Leeds, United Kingdom
Background/Purpose: Change in subchondral bone has been clinically associated with progression of osteoarthritis (OA). Modern image analysis techniques allow accurate, automated identification of bone in…
Abstract Number: 710 • 2012 ACR/ARHP Annual Meeting
Optical Density Measure of the Papillary Dermis Discriminates As Abnormal Clinically Uninvolved Skin in Systemic Sclerosis and Correlates with Severity of Skin Thickness
Giuseppina Abignano¹, Sibel Z. Aydin², Concepcion Castillo-Gallego³, Daniel Woods⁴, Adam Meekings⁵, Dennis McGonagle⁶, Paul Emery⁷ and Francesco Del Galdo⁸, ¹Chapel Allerton Hospital Leeds Insitute of Molecular medicine, Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ²Unit of Rheumatology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey, ³Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, ⁴Michelson Diagnostics Ltd, Kent, United Kingdom, ⁵Michelson Diagnostics Ltd, Kent, United Kingdom, Kent, United Kingdom, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ⁸Musculoskeletal Diseases, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom
Background/Purpose: Skin involvement in systemic sclerosis (SSc) is often primary outcome in clinical trials and its severity inversely correlates with prognosis. Nevertheless, an objective quantitative…
Abstract Number: 571 • 2012 ACR/ARHP Annual Meeting
Description of Distribution of Active Inflammatory Lesions On Magnetic Resonance Imaging of the Sacroiliac Joints and the Spine in Patients with Early Axial Spondyloarthritis – Analysis of the Esther Trial Baseline Data
In-Ho Song¹, Christian Althoff², Hildrun Haibel¹, Joachim Listing³, Anja Weiß⁴, Bruce Freundlich⁵, Martin Rudwaleit⁶ and Joachim Sieper⁷, ¹Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, ²Radiology, Charite Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ³German Rheumatism Research Center, Berlin, Germany, ⁴German Rheumatism Research Centre, Berlin, Germany, ⁵University of Pennsylvania, Philadelphia, PA, ⁶Endokrinologikum Berlin, Berlin, Germany, ⁷Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany
Background/Purpose: To address the question whether active inflammation starts at specific sites of the sacroiliac joints (SI-joints) and/ or the spine. Methods: Wb-MRIs of…
Abstract Number: 572 • 2012 ACR/ARHP Annual Meeting
Radiographic Damage in Ankylosing Spondylitis Over 12 Years of Follow-up: A Longitudinal Analysis
Sofia Ramiro¹, Carmen Stolwijk², A.M. Van Tubergen³, Désirée van der Heijde⁴ and Robert Landewé⁵, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, The Netherlands and Hospital Garcia de Orta, Almada, Portugal, ²Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ³Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands
Background/Purpose: Radiographic damage is one of the core outcomes recommended by the Assessment in Spondyloarthritis international Society (ASAS) for follow-up of patients with axial SpA.…
Abstract Number: 128 • 2012 ACR/ARHP Annual Meeting
Quantitative Assessment of Synovitis in Patients with Rheumatoid Arthritis Using Fluorescence Optical Imaging
Valentin S. Schäfer¹, Wolfgang Hartung², Patrick Hoffstetter³, Jörn Berger⁴, Martina Müller⁵, Martin Fleck² and Boris P. Ehrenstein², ¹Rheumatology & Clinical Immunology, Asklepios Klinikum Bad Abbach, Bad Abbach, Germany, ²Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, ³Radiology, Asklepios Klinikum Bad Abbach, Bad Abbach, Germany, ⁴mivenion GmbH, Berlin, Germany, ⁵Clinic for Internal Medicine I, University Clinic Regensburg, Regensburg
Background/Purpose: To prospectively evaluate quantitative assessment of indocyanine green (ICG)-enhanced fluorescence optical imaging (FOI) for differentiation of synovitic from non-synovitic joints in patients suffering from…

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