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Abstracts tagged "imaging techniques"

  • Abstract Number: 1950 • 2013 ACR/ARHP Annual Meeting

    Relationship Between Radiographic Joint Space Narrowing, Sonographic Cartilage Thickness and Anatomy In Rheumatoid Arthritis and Control Joints

    Peter Mandl1, Gabriela Supp2, Gabor Baksa3, Daniel Aletaha4, Reka Kurucz5, Dora Niedermayer6, Helga Radner7, Paul Studenic8, Peter V. Balint9 and Josef S. Smolen10, 1Medical University of Vienna, Vienna, Austria, 2Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Semmelweis University, Budapest, Hungary, 4Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria, 5National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 6PsAID taskforce, EULAR, Zurich, Switzerland, 7Department of Internal Medicine III; Division of Rheumatology, Medical University Vienna, Vienna, Austria, 8Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 9Rheumatology, National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 10Medical University of Vienna and Hietzing Hospital, Vienna, Austria

    Background/Purpose: To validate ultrasound (US) for measuring cartilage thickness, by evaluating cartilage thickness on cadaver specimens of metacarpophalangeal (MCP) joints by US and conventional measurement.…
  • Abstract Number: 1835 • 2013 ACR/ARHP Annual Meeting

    Dynamic Visualization Of Monocyte Migration In 3D Synovial Micromass Tissue Cultures

    Clemens Scheinecker1, Ruth Byrne1, Karolina Dalwigk2, Anastasiya Hladik1, Gunter Steiner3, Josef S. Smolen4 and Hans Peter Kiener1, 1Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Rheumatology, Medical University of Vienna, Vienna, Austria, 3Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 4Department of Medicine 3, Division of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria

    Background/Purpose: Monocytes (Mo) are among the first hematopoietic cells to migrate into the inflamed synovial tissue of arthritic joints. Monocyte migration appears to be associated…
  • Abstract Number: 1716 • 2013 ACR/ARHP Annual Meeting

    Childhood-Onset Systemic Lupus Erythematosus With Clinical Neurocognitive Dysfunction Have Lower Nodal Density and Connectivity On Diffusion Tensor Imaging

    Jordan T. Jones1, Mark DiFrancesco2, Ahmad I. Zaal1, Marisa S. Klein-Gitelman3, Darren Gitelman4, Jun Ying5 and Hermine Brunner1, 1Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Division of Rheumatology, Children's Memorial Hospital, Chicago, IL, 4Neurology, Northwestern University, Chicago, IL, 5Medicine-Internal Medicine-General Medicine, University of Cincinnati, Cincinnati, OH

    Background/Purpose: Neurocognitive dysfunction (NCD) is common in childhood-onset systemic lupus erythematosus (cSLE), and often difficult to detect with current resources.  Diffusion tensor imaging (DTI) is…
  • Abstract Number: 1308 • 2013 ACR/ARHP Annual Meeting

    Low Accuracy Of Radiograph Reports In Identifying Patients With Rheumatoid Arthritis In The Veterans Affairs Rheumatoid Arthritis Registry

    Maria P. Martes1, Alan R. Erickson2, Ted R. Mikuls2 and Grant W. Cannon3, 1Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 2Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 3Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT

      Background/Purpose:   The accurate interpretation of hand radiographs is critical in the diagnosis and management of rheumatoid arthritis (RA) patients.  This project determined first,…
  • Abstract Number: 1113 • 2013 ACR/ARHP Annual Meeting

    Scintigraphic Detection Of TNFα With a Radiolabeled Anti-TNFα In Patients With Active Peripheral Spondyloarthritis and Rheumatoid Arthritis

    Philippe Carron1, Bieke Lambert2, Filip De Vos3, Gust Verbruggen1, Dirk Elewaut1 and Filip van Den Bosch1, 1Rheumatology, Department of Rheumatology Ghent University Hospital, Ghent, Belgium, 2Department of Nuclear Medicine Ghent University Hospital, Department of Nuclear Medicine Ghent University Hospital, Ghent, Belgium, 3Radiopharmacy, Department of Radiopharmacy Ghent University, Ghent, Belgium

    Background/Purpose: Spondyloarthritis (SpA) and rheumatoid arthritis (RA) are the most common chronic inflammatory joint diseases, with a combined prevalence close to 2%. The pathogenetic role…
  • Abstract Number: 710 • 2012 ACR/ARHP Annual Meeting

    Optical Density Measure of the Papillary Dermis Discriminates As Abnormal Clinically Uninvolved Skin in Systemic Sclerosis and Correlates with Severity of Skin Thickness

    Giuseppina Abignano1, Sibel Z. Aydin2, Concepcion Castillo-Gallego3, Daniel Woods4, Adam Meekings5, Dennis McGonagle6, Paul Emery7 and Francesco Del Galdo8, 1Chapel Allerton Hospital Leeds Insitute of Molecular medicine, Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, 2Unit of Rheumatology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey, 3Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 4Michelson Diagnostics Ltd, Kent, United Kingdom, 5Michelson Diagnostics Ltd, Kent, United Kingdom, Kent, United Kingdom, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 7Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, 8Musculoskeletal Diseases, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom

    Background/Purpose: Skin involvement in systemic sclerosis (SSc) is often primary outcome in clinical trials and its severity inversely correlates with prognosis. Nevertheless, an objective quantitative…
  • Abstract Number: 571 • 2012 ACR/ARHP Annual Meeting

    Description of Distribution of Active Inflammatory Lesions On Magnetic Resonance Imaging of the Sacroiliac Joints and the Spine in Patients with Early Axial Spondyloarthritis – Analysis of the Esther Trial Baseline Data

    In-Ho Song1, Christian Althoff2, Hildrun Haibel1, Joachim Listing3, Anja Weiß4, Bruce Freundlich5, Martin Rudwaleit6 and Joachim Sieper7, 1Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, 2Radiology, Charite Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, 3German Rheumatism Research Center, Berlin, Germany, 4German Rheumatism Research Centre, Berlin, Germany, 5University of Pennsylvania, Philadelphia, PA, 6Endokrinologikum Berlin, Berlin, Germany, 7Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany

    Background/Purpose: To address the question whether active inflammation starts at specific sites of the sacroiliac joints (SI-joints) and/ or the spine.   Methods: Wb-MRIs of…
  • Abstract Number: 572 • 2012 ACR/ARHP Annual Meeting

    Radiographic Damage in Ankylosing Spondylitis Over 12 Years of Follow-up: A Longitudinal Analysis

    Sofia Ramiro1, Carmen Stolwijk2, A.M. Van Tubergen3, Désirée van der Heijde4 and Robert Landewé5, 1Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, The Netherlands and Hospital Garcia de Orta, Almada, Portugal, 2Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 3Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands

    Background/Purpose: Radiographic damage is one of the core outcomes recommended by the Assessment in Spondyloarthritis international Society (ASAS) for follow-up of patients with axial SpA.…
  • Abstract Number: 128 • 2012 ACR/ARHP Annual Meeting

    Quantitative Assessment of Synovitis in Patients with Rheumatoid Arthritis Using Fluorescence Optical Imaging

    Valentin S. Schäfer1, Wolfgang Hartung2, Patrick Hoffstetter3, Jörn Berger4, Martina Müller5, Martin Fleck2 and Boris P. Ehrenstein2, 1Rheumatology & Clinical Immunology, Asklepios Klinikum Bad Abbach, Bad Abbach, Germany, 2Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, 3Radiology, Asklepios Klinikum Bad Abbach, Bad Abbach, Germany, 4mivenion GmbH, Berlin, Germany, 5Clinic for Internal Medicine I, University Clinic Regensburg, Regensburg

    Background/Purpose: To prospectively evaluate quantitative assessment of indocyanine green (ICG)-enhanced fluorescence optical imaging (FOI) for differentiation of synovitic from non-synovitic joints in patients suffering from…
  • Abstract Number: 2546 • 2012 ACR/ARHP Annual Meeting

    Tofacitinib Inhibits Radiographic Progression in Patients with Rheumatoid Arthritis Prone to Develop Structural Damage: A Post-Hoc Analysis of a Phase 3 Trial

    Désirée van der Heijde1, Robert B. M. Landewé2 and David Gruben3, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands, 3Pfizer Inc., Groton, CT

    Background/Purpose: Tofacitinib is a novel, oral Janus kinase inhibitor being investigated as a targeted immunomodulator and disease-modifying therapy for RA. In the ORAL Scan trial…
  • Abstract Number: 132 • 2012 ACR/ARHP Annual Meeting

    FDG-PET Evaluation of Axillary Lymph Nodes and Large Joints of Patients with Rheumatoid Arthritis Treated with Anti-TNF Drugs

    Koichi Okamura1, Yukio Yonemoto2, Tetsuya Kaneko3, Kimihiko Takeuchi4, Tsutomu Kobayashi1 and Kenji Takagishi1, 1Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan, 2Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan, 3Department of Orthopaedic Surgery, Inoue Hospital, Takasaki, Gunma, Japan, 4Department of Rheumatology, Isesaki Fukushima Hospital, Isesaki, Gunma, Japan

    Background/Purpose: F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) can be used to image synovial inflammation in patients with rheumatoid arthritis (RA). The development of molecular…
  • Abstract Number: 2350 • 2012 ACR/ARHP Annual Meeting

    Similarities Exceeds Differences in the Pattern of Joint and Vascular Positron Emission/Computed Tomography Uptake in Polymyalgia Rheumatica and Giant Cell Arteritis

    Dario Camellino1, Silvia Morbelli2, Francesco Paparo3, Michela Massollo2, Gianmario Sambuceti4 and Marco A. Cimmino5, 1Dipartimento Medicina Interna, Clinica Reumatologica, Genova, Italy, 2Dipartimento Medicina Interna, Medicina Nucleare, Genova, Italy, 3Radiology Unit, E.O. Ospedali Galliera, Genoa, Italy, 4Dipartimento di Medicina Interna, Medicina Nucleare, Genova, Italy, 5Department of Internal Medicine, Academic Unit of Clinical Rheumatology, University of Genova, Genova, Italy

    Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are two frequent overlapping diseases. The purpose of this work is to examine the relationship between…
  • Abstract Number: 1486 • 2012 ACR/ARHP Annual Meeting

    Poor Outcome in Patients with Systemic Sclerosis and Myocardial Involvement: A Combined Approach Based On Clinical and Laboratory Findings, EKG-Holter and Cardiac Magnetic Resonance

    Silvia Laura Bosello, Giacomo De Luca, Antonella Laria, Giorgia Berardi and Gianfranco Ferraccioli, Division of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy

    Background/Purpose: Cardiac involvement is a relevant prognostic determinant in Systemic Sclerosis (SSc), but the diagnosis is often delayed due to the lack of a specific…
  • Abstract Number: 1119 • 2012 ACR/ARHP Annual Meeting

    Prediction of MRI-Detected Cartilage Loss Over 30 Months Using Simplified Radiographic and Clinical Stratification: The MOST Study

    Frank Roemer1, David T. Felson2, Jingbo Niu3, Yuqing Zhang2, Michael C. Nevitt4, Michel Crema5, Cora E. Lewis6, James Torner7 and Ali Guermazi5, 1Klinikum Augsburg, Augsburg, Germany, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 4Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 5Boston University, Boston, MA, 6Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, 7Epidemiology, University of Iowa, Iowa City, Iowa City, IA

    Background/Purpose: MRI-detected cartilage loss is the main structural outcome measure in large studies of knee OA. Definition of subjects at high risk for cartilage loss…
  • Abstract Number: 1042 • 2012 ACR/ARHP Annual Meeting

    Psoriatic Arthritis Patients Assessed by Dynamic Contrast-Enhanced MRI in High Disease Versus Minimal Disease Activity State – a Cross-Sectional Study Correlating Conventional MRI and Clinical Composite Measures

    René Panduro Poggenborg1, Pernille Bøyesen2, Charlotte Wiell3, Susanne Juhl Pedersen4, Inge Juul Sørensen5, Ole Rintek Madsen6, Ole Slot1, Jakob M. Møller7, Mikael Boesen8, Henning Bliddal9, Olga Kubassova10 and Mikkel Østergaard11, 1Department of Rheumatology, Copenhagen University Hospital in Glostrup, Copenhagen, Denmark, 2Rheumatology, Diakonhjemmet Hospital, Olso, Norway, 3Department of Rheumatology, Copenhagen University Hospital in Gentofte, Copenhagen, Denmark, 4Department of Rheumatology, Copenhagen University Hospital Glostrup, Copenhagen, Denmark, 5Department of Rheumatology, Glostrup Hospital, Copenhagen, Denmark, 6DANBIO, On behalf of Depts of Rheumatology, North, South, Central, Zealand and Capital Region, Copenhagen, Denmark, 7Department of Radiology, Copenhagen University Hospital at Herlev, Copenhagen, Denmark, 8The Parker Institute, Department of Rheumatology, Copenhagen University Hospital at Frederiksberg, Copenhagen, Denmark, 9The Parker Institute, Department of Rheumatology, Copenhagen University Hospital at Frederiksberg, Frederiksberg, Denmark, 10Image Analysis Ltd., Leeds, United Kingdom, 11Dept of Rheumatology RM, Glostrup Hospital, Glostrup, Denmark

    Background/Purpose: Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) has been validated in rheumatoid arthritis for measuring inflammation, but has rarely been studied in psoriatic arthritis…
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