ACR Meeting Abstracts

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Abstracts tagged "Imaging techniques and systemic sclerosis"

  • Abstract Number: 2669 • 2017 ACR/ARHP Annual Meeting

    Microvascular Flow Assessed By Dynamic Optical Coherence Tomography: First Non-Invasive Quantitative Outcome Measure of Microvascular Disease in Systemic Sclerosis

    Giuseppina Abignano1,2, Alexandra Daniel1,3, Lorraine Green1,3, Sookhoe Eng1,3, Paul Emery1,3 and Francesco Del Galdo1,3, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Rheumatology Institute of Lucania (IReL), Potenza, Italy, 3Leeds Musculoskeletal Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Virtual skin biopsy by Optical Coherence Tomography (OCT) has been proposed as quantitative outcome measure of fibrosis in Systemic Sclerosis (SSc). Dynamic OCT (D-OCT)…
  • Abstract Number: 850 • 2016 ACR/ARHP Annual Meeting

    A Multicentre Reliability Study of Laser Speckle Contrast Imaging and Thermography in Patients with Raynaud’s Phenomenon Secondary to Systemic Sclerosis

    Andrea Murray1, Joanne Manning2, Tonia Moore3,4, Jack Wilkinson5, Elizabeth J. Marjanovic6, Sarah Leggett7, Chris Roberts8, John Allen9, Jason Britton10, Maya H. Buch11, Francesco Del Galdo12, Christopher Denton13, Tracey Drayton14, Anita Furlong14, Bridget Griffiths15, Frances Hall16, Darren Hart17, Kevin Howell18, Audrey MacDonald19, Neil J. McHugh20, John D. Pauling21, Jacqueline Shipley22 and Ariane L. Herrick23, 1University of Manchester, Salford Royal Hospital, Salford, United Kingdom, 2Rheumatology Department, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 3Salford Royal Hospital NHS Foundation Trust, Salford, United Kingdom, 4Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Salford, United Kingdom, 5Research and Development, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 6Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, 7Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, 8Centre for Biostatistics, The University of Manchester, Manchester, United Kingdom, 9Regional Medical Physics Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom, 10Medical Physics Department, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 11NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 12Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 13Division of Medicine, Centre for Rheumatology and Connective Tissue Disease, University College London, London, United Kingdom, 14Addenbrookes Hospital, Cambridge, United Kingdom, 15Rheumatology, Freeman Hospital, Newcastle Upon Tyne, United Kingdom, 16School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom, 17Clinical Measurement Department, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 18Institute of Immunity and Transplantation, University College London, Royal Free Campus, London, United Kingdom, 19The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom, 20Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 21Upper Borough Walls, Royal National Hospital for Rheumatic Disease, Bath, United Kingdom, 22Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 23Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Manchester, United Kingdom

    Background/Purpose: Effective treatments for systemic sclerosis (SSc) related Raynaud’s phenomenon (RP) are badly needed but clinical trials have been hampered by the lack of objective…
  • Abstract Number: 1863 • 2016 ACR/ARHP Annual Meeting

    Non-Invasive Investigation of Perfusion, Microvascular Structure, Erythema, Oxidative Stress and Oxygenation in Healthy Controls and in Patients with Primary and Secondary Raynaud’s Phenomenon

    Andrea Murray1,2, Tonia Moore3, Joanne Manning4, Ian Poxon2, Graham Dinsdale1, Michael Berks5, Sarah Leggett6, Mark Dickinson2 and Ariane L. Herrick1, 1Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Manchester, United Kingdom, 2Photon Science institute, University of Manchester, Manchester, United Kingdom, 3Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Salford, United Kingdom, 4Rheumatology Department, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 5Centre for Imaging Sciences, University of Manchester, Institute of Population Health, Manchester, United Kingdom, 6Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom

    Background/Purpose: It is well established that measurements of cutaneous microvascular dysfunction (measured with laser Doppler imaging [LDI]) and structural abnormality (measured with nailfold capillaroscopy [NC])…
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