Abstracts tagged "il7 and lymphocytes"

Abstract Number: 2423 • 2019 ACR/ARP Annual Meeting
In Primary Sjogren’s Syndrome (pSS) IL7 Promotes the Crosstalk Between T Lymphocytes and Salivary Gland Epithelial Cells and Participates to IFN Signature
Gaetane Nocturne¹, Juliette Pascaud ², Elodie Rivière ³, Alexandre Virone ⁴, Anastasia Dupré ², Vanessa Gauttier ⁵, Nicolas Poirier ⁵ and Xavier Mariette ⁶, ¹Université Paris Sud, Le Kremlin Bicetre, France, ²IMVA - IDMIT, CEA - Université Paris Sud - INSERM U1184, Le Kremlin Bicêtre, Paris, France, ³IDMIT, CEA - Université Paris Sud - INSERM U1184, Le Kremlin Bicêtre ; Arthritis R&D, France, Paris, France, ⁴Université Paris Sud, Le Kremlin Bicetre, ⁵OSE Immunotherapeutics, Nantes, France, ⁶Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France
Background/Purpose: pSS is characterized by lymphocytic infiltration of salivary gland epithelial cells (SGEC). This infiltrate is made of T (TL) and B (BL) lymphocytes. SGEC…

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