Abstracts tagged "IL-6 and atherosclerosis"

Abstract Number: 439 • 2014 ACR/ARHP Annual Meeting
The Anti-IL-6 Antibody Sirukumab Inhibits Vascular Inflammation in a Human Surrogate Model of Atherosclerosis
Ryan Feaver¹, Sol Collado², Stephen Hoang², Erica Berzin², Allison Armstrong³, Debbie Gardner⁴, Paul Fisher⁵, Hao Liu⁶, Aaron Mackey², David Manka², Brian Wamhoff², David Shealy⁴ and Brett Blackman², ¹HemoShear, LLC, Charlottesville, VA, ²HemoShear, LLC., Charlottesville, VA, ³HemoShear, LLC., Virginia, VA, ⁴Janssen Research & Development, LLC, Spring House, PA, ⁵Janssen Research & Development, LLC., Spring House, PA, ⁶Immunology Research, Janssen Research and Development, LLC., Spring House, PA
Background/Purpose: Rheumatoid arthritis (RA) and atherosclerosis are chronic inflammatory diseases that share many biological features. Prevalence of atherosclerosis is increased by approximately 2-fold in RA,…

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Abstracts tagged "IL-6 and atherosclerosis"

The Anti-IL-6 Antibody Sirukumab Inhibits Vascular Inflammation in a Human Surrogate Model of Atherosclerosis