Abstracts tagged "IL-23 and toll-like receptors"

Abstract Number: 713 • ACR/ARHP Annual Meeting 2013
Interferon Regulatory Factor 2 Haploinsufficiency Deteriorates Imiquimod-Induced Psoriasis-Like Skin Inflammation
Takayuki Kimura¹, Makoto Sugaya², Makiko Kawaguchi¹, Sohshi Morimura¹, Hiraku Suga¹ and Shinichi Sato³, ¹Department of Dermatology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan, ²Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan, ³Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
Background/Purpose: Psoriasis is a T-cell-mediated immunological skin disease with a complex pathogenesis where both genetic and environmental factors are involved. Interferon regulatory factor (IRF)-2 is one…