Abstracts tagged "IL-23 and spondylarthritis"

Abstract Number: 2877 • 2019 ACR/ARP Annual Meeting
Safety and Efficacy Results from the Open Label Extension of a Phase 2 Trial of Risankizumab, a Selective IL-23p19 Inhibitor in Patients with Active Psoriatic Arthritis
Kim Papp¹, Melinda Gooderham ², Akimichi Morita ³, Alan Kivitz ⁴, Ranjeeta Sinvhal ⁵, Andrew Topp ⁵, Graham Heap ⁵, Ann Eldred ⁵ and Philip Mease ⁶, ¹K. Papp Clinical Research and Probity Medical Research, Waterloo, ON, Canada, Waterloo, ON, Canada, ²2School of Medicine, Queen’s University, Kingston, ON and Skin Centre for Dermatology and Probity Medical Research, Peterborough, ON, Canada, ³Dept of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, ⁴Altoona Center for Clinical Research, Duncansville, PA, ⁵AbbVie Inc., North Chicago, ⁶Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA
Background/Purpose: Psoriatic arthritis (PsA) is characterized by peripheral synovitis, enthesitis, dactylitis and spondylitis, and IL-23 is involved in the pathogenesis of these conditions either directly…

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