ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "IL-17A"

  • Abstract Number: L20 • 2019 ACR/ARP Annual Meeting

    A Head-to-Head Comparison of Ixekizumab and Adalimumab in Biologic-Naïve Patients with Active Psoriatic Arthritis: Efficacy and Safety Outcomes from a Randomized, Open-Label, Blinded Assessor Study Through 52 Weeks

    Josef Smolen1, Peter Nash 2, Hasan Tahir 3, Hendrik Schulze-Koops 4, Lingnan Li 5, Maja Hojnik 6, Amanda Gellett 5, Soyi Liu-Leage 7, Sreekumar Pillai 7 and Philip J. Mease 8, 1Medical University of Vienna, Vienna, Austria, 2Griffith University, Brisbane, Queensland, Australia, 3Royal Free London NHS Trust, London, United Kingdom, 4Department of Rheumatology/Clinical Immunology, Ludwig-Maximilians-University Munich, Munich, Germany, 5Eli Lilly and Company, Indianapolis, Indiana, 6Eli Lilly and Company, Indianapolis, IN, 7Eli Lilly and Company, Indianapolis, 8Swedish Medical Center and University of Washington, Seattle, Washington

    Background/Purpose: Multiple biologic DMARDs (bDMARDs) are available for treatment of PsA, but there are few direct comparisons of their efficacy and safety. Furthermore, efficacy of…
  • Abstract Number: 1010 • 2019 ACR/ARP Annual Meeting

    IL-17A Induces Distinct Functional Differences Between Two Novel Mesenchymal Stem Cell Populations Identified at the Human Enthesis

    Tobias Russell1, Abdulla Watad 2, Charlie Bridgewood 3, Almas Khan 4, Abhay S Rao 4, Peter Loughenbury 4, Peter Milner 4, Robert Dunsmuir 4, Thomas Baboolal 3, Elena Jones 5, Richard Cuthbert 1 and Dennis McGonagle 6, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM)University of Leeds, Leeds, England, United Kingdom, 2Department of Medicine “B”, Zabludowicz Center for Autoimmune Diseases Sheba Medical Center, Ramat-Gan, Israel, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM)University of Leeds, Leeds, United Kingdom, 4Leeds Teaching Hospitals NHS Trust, Leeds, 5University of Leeds, Leeds, England, United Kingdom, 6University of Leeds, Leeds, United Kingdom

    Background/Purpose: Ankylosing spondylitis (AS) is associated with entheseal inflammation and new bone formation. Resident populations of lymphocytes have been identified at the enthesis that on…
  • Abstract Number: 1553 • 2019 ACR/ARP Annual Meeting

    Impact of Peripheral Swollen and Tender Joints at Baseline on Response to Treatment with Secukinumab in Ankylosing Spondylitis

    Philip Mease1, Atul Deodhar 2, Renato Calheiros 3, Xiangyi Meng 3, Todd Fox 4 and Xenofon Baraliakos 5, 1Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA, 2Oregon Health & Science University, Portland, OR, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Novartis Pharma AG, Basel, Switzerland, 5Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany

    Background/Purpose: AS is a chronic, inflammatory disease of the axial skeleton associated with pain, stiffness, disability, and reduced quality of life (QOL).1 AS is defined…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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