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Abstracts tagged "IL-1 and polymorphism"

  • Abstract Number: 1703 • ACR/ARHP Annual Meeting 2013

    High Density Genotyping Of Immune-Related Disease Genes Identifies 7 New Susceptibility Loci For Behçet’s Disease

    Masaki Takeuchi1,2, Nobuhisa Mizuki2, Akira Meguro2, Michael J. Ombrello3, Colleen Satorius4, Yohei Kirino2, Tatsukata Kawagoe2, Duran Ustek5, Ilknur Tugal-tutkun6, Emire Seyahi7, Yilmaz Ozyazgan7, Shigeaki Ohno8, Atsuhisa Ueda2, Yoshiaki Ishigatsubo2, Ahmet Gül6,9, Daniel L. Kastner4 and Elaine Remmers4, 1Medical Genetics Branch, Inflammation Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 2Yokohama City University Graduate School of Medicine, Yokohama, Japan, 3Translational Genetics and Genomics Unit, National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 5Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey, 6Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, 7Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey, 8Hokkaido University Graduate School of Medicine, Hokkaido, Japan, 9Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: Genome-wide association studies have revealed susceptibility genes for many genetically complex diseases. The Immunochip is a custom array with 196,524 markers in 186 loci…

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