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Abstracts tagged "IL-1 and anakinra"

  • Abstract Number: 1203 • ACR/ARHP Annual Meeting 2013

    An Escalating Dose Of Anakinra In Patients With Autoinflammatory Disease Is a Safe and Reasonable Therapeutic Option

    Amanda K. Ombrello1, Karyl Barron2, Patrycja M. Hoffmann3, Anne Jones3, Deborah Stone4 and Daniel L. Kastner5, 1National Human Genome Research Institute,National Institute of Health, Bethesda, MD, 2Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 3Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 4National Human Genome Research Institute, Bethesda, MD, 5Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, MD

    Background/Purpose:   The autoinflammatory diseases are diseases in which there is seemingly unprovoked stimulation of the innate immune system.  The enhanced release of cytokines in…

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