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Abstracts tagged "hypertension and pediatric rheumatology"

  • Abstract Number: 2030 • ACR/ARHP Annual Meeting 2018

    Patients with Childhood-Onset SLE (cSLE) and Hypertension Have Consistently Higher Serum Concentrations of C3 and C4 Than Those without Hypertension

    Evan Mulvihill1, Stacy P. Ardoin2, Susan D Thompson3, Bi Zhou4, Gakit Yu5, Nora G. Singer6, Deborah M. Levy7, Hermine I. Brunner8, Yee Ling Wu9, Haikady Nagaraja10, Laura E. Schanberg11 and Chack-Yung Yu2, 1Pediatrics and Rheumatology, Nationwide Children's Hospital, Columbus, OH, 2Division of Rheumatology, Nationwide Children’s Hospital, Columbus, OH, 3Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH, 5Center for Molecular and Human Genetics, Nationwide Children's Hospital, Columbus, OH, 6Departments of Medicine and Pediatrics, Division of Rheumatology, MetroHealth Medical Center, Cleveland, OH, Cleveland, OH, 7Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 8Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 9Department of Microbiology and Immunology, Loyola University Chicago, Chicago, IL, 10College of Public Health, The Ohio State University, Columbus, OH, 11Duke University Medical Center, Durham, NC

    Background/Purpose: Chronic systemic inflammation, mediated in part by complement, and inadequate vascular repair mechanisms affect patients with cSLE from a young age and are associated…

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