Abstracts tagged "hypertension and pediatric rheumatology"

Abstract Number: 2030 • 2018 ACR/ARHP Annual Meeting
Patients with Childhood-Onset SLE (cSLE) and Hypertension Have Consistently Higher Serum Concentrations of C3 and C4 Than Those without Hypertension
Evan Mulvihill¹, Stacy P. Ardoin², Susan D Thompson³, Bi Zhou⁴, Gakit Yu⁵, Nora G. Singer⁶, Deborah M. Levy⁷, Hermine I. Brunner⁸, Yee Ling Wu⁹, Haikady Nagaraja¹⁰, Laura E. Schanberg¹¹ and Chack-Yung Yu², ¹Pediatrics and Rheumatology, Nationwide Children's Hospital, Columbus, OH, ²Division of Rheumatology, Nationwide Children’s Hospital, Columbus, OH, ³Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH, ⁵Center for Molecular and Human Genetics, Nationwide Children's Hospital, Columbus, OH, ⁶Departments of Medicine and Pediatrics, Division of Rheumatology, MetroHealth Medical Center, Cleveland, OH, Cleveland, OH, ⁷Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ⁸Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ⁹Department of Microbiology and Immunology, Loyola University Chicago, Chicago, IL, ¹⁰College of Public Health, The Ohio State University, Columbus, OH, ¹¹Duke University Medical Center, Durham, NC
Background/Purpose: Chronic systemic inflammation, mediated in part by complement, and inadequate vascular repair mechanisms affect patients with cSLE from a young age and are associated…

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