Abstract Number: 619 • 2014 ACR/ARHP Annual Meeting
Effect of ERAP1 Knockdown on Conformation of HLA-B27 and Other HLA Class I Molecules in Human Monocytic Cells
Background/Purpose Polymorphisms in endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1) are associated with ankylosing spondylitis, Behcet’s disease, and psoriasis/psoriatic arthritis, where HLA class I alleles are…