Abstracts tagged "Hsp90 and systemic sclerosis"

Abstract Number: 2613 • 2019 ACR/ARP Annual Meeting
Hsp90 as a Potential Biomarker of Lung and Skin Involvement in Patients with Systemic Sclerosis
Hana Storkanova¹, Sabina Oreska ², Maja Spiritovic ³, Barbora Hermankova ⁴, Kristyna Bubova ¹, Martin Komarc ⁵, Karel Pavelka ², Jiri Vencovsky ¹, Jörg Distler ⁶, Ladislav Senolt ², Radim Becvar ² and Michal Tomcik ², ¹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague, Czech Republic, ²Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, ³Faculty of Physical Education and Sport, Department of Physiotherapy, Charles University, Prague, Czech Republic, Prague 2, Hlavni mesto Praha, Czech Republic, ⁴Faculty of Physical Education and Sport, Department of Physiotherapy, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁵Department of Methodology, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁶Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany
Background/Purpose: Our previous study demonstrated that Hsp90 is overexpressed in the skin of patients with systemic sclerosis (SSc), in cultured SSc fibroblasts and preclinical models…

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