Abstracts tagged "HR-pQCT"

Abstract Number: 2207 • 2019 ACR/ARP Annual Meeting
Bone Mineral Density and Microarchitecture Among Chinese Patients with Rheumatoid Arthritis
Shangyi Jin¹, Evelyn Hsieh ², Weibo Xia ³, Mengtao Li ⁴, Qian Wang ¹ and Xiaofeng Zeng ¹, ¹Department of Rheumatology, Key Laboratory of Rheumatology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, People’s Republic of China, Beijing, Beijing, China (People's Republic), ²Section of Rheumatology, Yale School of Medicine, NewHaven, CT, ³Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, Beijing, China (People's Republic), ⁴Dept. of Rheumatology, Peking Union Medical College Hospital (West Campus), Beijing, China, Beijing, China (People's Republic)
Background/Purpose: To evaluate alterations of bone mineral density and microarchitecture in patients with rheumatoid arthritis (RA). We also aimed to identify potential factors associated with…
Abstract Number: 652 • 2018 ACR/ARHP Annual Meeting
Disease Interception in Psoriasis Patients with Subclinical Joint Inflammation By Interleukin 17 Inhibition with Secukinumab – Data from a Prospective Open Label Study
Eleni Kampylafka¹, Isabelle Oliveira¹, Christina Linz², Veronika Lerchen¹, Matthias Englbrecht¹, David Simon³, Michael Sticherling⁴, Juergen Rech⁵, Arnd Kleyer³, Georg Schett⁶ and Axel J. Hueber³, ¹Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, ²Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, e, Germany, ³Department of Internal Medicine 3—Rheumatology and Immunology, Friedrich-Alexander-University Erlangen–Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, ⁴Department of Dermatology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, ⁵Universitätsklinikum Erlangen, Erlangen, Germany, ⁶Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Musculoskeletal changes precede the onset of psoriatic arthritis (PsA). A subset of psoriasis patients is characterized by arthralgia as well as inflammatory changes in…
Abstract Number: 1369 • 2018 ACR/ARHP Annual Meeting
The Influence of Hand Osteoarthritis on Bone Microstructure and Biomechanical Properties of Radial Bone
David Simon, Sara Unbehend, Sara Bayat, Juergen Rech, Axel J. Hueber, Georg Schett and Arnd Kleyer, Department of Internal Medicine 3—Rheumatology and Immunology, Friedrich-Alexander-University Erlangen–Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany
Background/Purpose: Primary hand osteoarthritis (HOA) is a heterogeneous disease, with erosive and osteoproliferative changes of the finger joints. [1] Due to the lack of treatment…
Abstract Number: 1459 • 2018 ACR/ARHP Annual Meeting
Bone Erosion Volume Changes Measured By HR-pQCT at 3-Months after Initiation of Anti-TNF Treatment Predicted Erosion Volume Changes at 1-Year in RA
Tomohiro Shimizu¹, Kenji Mamoto¹, Matthew Tanaka¹, Andrew J Burghardt², Thomas Link¹, Jonathan Graf³, John B. Imboden Jr.³ and Xiaojuan Li¹, ¹Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ³Medicine, University of California, San Francisco, San Francisco, CA
Background/Purpose: Bone erosions and joint space narrowing (JSN) are significant aspects of structural damage in rheumatoid arthritis. High resolution peripheral quantitative computed tomography (HR-pQCT) allows…
Abstract Number: 2206 • 2018 ACR/ARHP Annual Meeting
Joint Repair While Initiating Biologic Therapy in Rheumatoid Arthritis
Scott Brunet^1,2,3, Sarah Manske^1,2,3, Klaus Engelke^4,5, Steven K. Boyd^1,2,3 and Cheryl Barnabe^2,6, ¹Biomedical Engineering, University of Calgary, Calgary, AB, Canada, ²McCaig Institute for Bone and Joint Health, Calgary, AB, Canada, ³Department of Radiology, University of Calgary, Calgary, AB, Canada, ⁴Institute of Medical Physics, University of Erlangen, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Department of Medicine, Erlangen University Hospital, Erlangen, Germany, ⁶Division of Rheumatology, University of Calgary, Calgary, AB, Canada
Background/Purpose: Functional decline and reduced quality of life for patients with rheumatoid arthritis (RA) results from chronic changes to joints in patients, including bone erosions…
Abstract Number: 2210 • 2018 ACR/ARHP Annual Meeting
Effects of Anti-Citrullinated Peptide Antibody (ACPA) on Bone Microstructure in Rheumatoid Arthritis: A HR-pQCT Study
Ikuko Tanaka¹, Takashi Kato², Motokazu Kai³, Kunikazu Ogawa³, Hiroaki Mizuno¹, Mari Ushikubo⁴, Keisuke Izumi⁵, Hisaji Oshima⁶ and Shigenori Tamaki¹, ¹Nagoya Rheumatology Clinic, Nagoya, Japan, ²Department of Radiology, National Center for Geratrics and Gerontology, Obu, Japan, ³Mie Rheumatology Clinic, Suzuka, Japan, ⁴National Tokyo Medical Center, Tokyo, Japan, ⁵Department of connective Tissue Disease, National Tokyo Medical Center, Tokyo, Japan, ⁶Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan
Background/Purpose: Rheumatoid arthritis (RA) induces systemic osteoporosis as well as osteoporotic change in the bones having arthritis by RA. Recently immune complex and anti-citrullinated peptide…
Abstract Number: 2212 • 2018 ACR/ARHP Annual Meeting
Feasibility and Performance of HR-pQCT-Derived Joint Space Width Measurement As Outcome Parameter in Arthropathic Disease – Lessons from Hemochromatosis Arthropathy
Ursula Heilmeier¹, Andrew J Burghardt¹, Puneet Kapoor², Georg Schett³, Reinhard Voll⁴ and Stephanie Finzel⁵, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA, ³Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany, ⁴Clinic for Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ⁵Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Background/Purpose: High resolution peripheral quantitative computed tomography (HR-pQCT) allows in vivo 3 D imaging of human joint microstructure and joint space width (JSW) at an…
Abstract Number: 2329 • 2018 ACR/ARHP Annual Meeting
Carotid Atherosclerosis Is Associated with Compromised Volumetric Bone Mineral Density and Microarchitecture in Patients with Inflammatory Arthritis
Isaac T. Cheng¹, Qing Shang², Edmund Kwok Ming Li², Priscilla Wong¹, Emily WL Kun³, Martin Li⁴, Tena K. Li¹, Tracy Y. Zhu⁵, PW Alex Lee², Ling Qin⁶ and Lai-Shan Tam⁴, ¹Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, Hong Kong, China, ²Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ³Department of Medicine, Tai Po Hospital, Hong Kong, Hong Kong, ⁴Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ⁵Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, ⁶Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Inflammatory arthritis patients had increased risk of atherosclerosis and osteoporosis. The association between presence of carotid plaque and volumetric BMD (vBMD)/microarchitecture is yet to…
Abstract Number: 1268 • 2017 ACR/ARHP Annual Meeting
Risk Factors for Bone Loss in Juvenile-Onset Systemic Lupus Erythematosus: A Prospective Study
Luiz A Sousa¹, Juliane Paupitz¹, Nadia E Aikawa², Liliam Takayama¹, Valéria F. Caparbo¹ and Rosa M R Pereira³, ¹Rheumatology Division, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil, ³Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil
Background/Purpose: Juvenile-onset systemic lupus erythematosus (JoSLE) is associated with low bone mass for age and fractures, nevertheless risk factors and predictors of bone involvement are…
Abstract Number: 1995 • 2017 ACR/ARHP Annual Meeting
Analysis of Erosion Volume of the Distal Radius By HR-pQCT in Patients with Rheumatoid Arthritis
Ko Chiba¹, Naoki Iwamoto², Makoto Osaki¹ and Atsushi Kawakami², ¹Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Background/Purpose: HR-pQCT is a high resolution CT dedicated to human extremities. It has been used mainly for osteoporosis, while in more recent years it has…
Abstract Number: 1996 • 2017 ACR/ARHP Annual Meeting
Changes in Cartilage Matrix Measured By MR T1ρ Are Correlated with Changes in Bone Erosion Volume Measured By HR-pQCT Three Months after MTX and Anti-TNF Treatment in Patients with Rheumatoid Arthritis: A Multi-Modality Imaging Study
Tomohiro Shimizu^1,2,3, Kenji Mamoto¹, Ursula Heilmeier¹, Matthew Tanaka¹, Andrew J Burghardt¹, Thomas Link¹, Jonathan Graf⁴, John B. Imboden Jr.⁵ and Xiaojuan Li⁶, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ²Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, ³Department of Orthopaedic Surgery, Hokkaido University, Sapporo, Japan, ⁴Department of Medicine, Division of Rheumatology Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, ⁵Medicine, University of California, San Francisco, San Francisco, CA, ⁶Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA
Background/Purpose: MR-based T1rho relaxation time mapping allows non-invasive quantification of early cartilage deterioration, while high-resolution peripheral quantitative computed tomography (HR-pQCT) can detect early changes in…
Abstract Number: 1219 • 2017 ACR/ARHP Annual Meeting
Associations between Muscle Mass and Function with Bone Microarchitecture and Bone Strength in Postmenopausal Women
Daniel Lobo¹, Jackeline C Alvarenga¹, Diogo S Domiciano², Fabiana Benatti¹, Bruno Gualano¹ and Rosa M R Pereira², ¹Rheumatology Division, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil
Background/Purpose: Most studies on sarcopenia and osteoporosis involve elderly populations. However, because postmenopausal hypoestrogenism is able to negatively modulate bone and muscle mass, it is…
Abstract Number: 158 • 2016 ACR/ARHP Annual Meeting
Musculoskeletal Ultrasound Is a Sensitive Imaging Tool for the Assessment of Dynamic Changes of Bone Erosions in Inflammatory Arthritis: A Comparative Analysis with High-Resolution Peripheral Quantitatve Computed Tomography
Stephanie Finzel^1,2, Marina Backhaus³, Sebastian Kraus⁴, Georg Schett⁵ and Reinhard Voll⁶, ¹Department of Rheumatology and Clinical Immunology, Medical Faculty, University Medical Center, University of Freiburg, Freiburg, Germany, ²Department of Internal Medicine III, Rheumatology and Immunology, University of Erlangen, 91054, Germany, ³Rheumatology, Park-Klinik Weissensee, Berlin, Germany, ⁴Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁶Dpt. Rheumatology & Clinical Immunology and Centre for Chronic Immunodeficiency, University Hospital Freiburg, University Medical Center, University of Freiburg, Freiburg, Germany
Background/Purpose: Correct detection of bone erosions is crucial both for diagnosis and for monitoring of treatment response in patients with inflammatory joint diseases. Musculoskeletal ultrasound…
Abstract Number: 326 • 2016 ACR/ARHP Annual Meeting
Cortical Bone Changes in Pre- and Postmenopausal Healthy Women Measured with HR-pQCT
Jackeline Couto Alvarenga¹ and Rosa M R Pereira², ¹Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil
Background/Purpose: Increased fracture rates are well-recognized in adults with trabecular and cortical bone deficits, but cortical evaluation has been poorly studied. The aim of this…
Abstract Number: 339 • 2016 ACR/ARHP Annual Meeting
Assessment of High-Resolution Peripheral Quantitative Computed Tomography Parameters and Markers of Bone Metabolism in Community-Dwelling Elderly with and without Vertebral Fractures – the Sao Paulo Ageing & Health Study
Geórgea H. F. Torres¹, Luis F S Guzman², Jaqueline C. Alvarenga³, Levi H J Neto³, Valéria F. Caparbo³, Diogo S Domiciano³, Ricardo M. Oliveira⁴, Neusa H M Lopes² and Rosa M R Pereira⁵, ¹Reumatologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Cardiologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴RDO Diagnósticos Médicos, São Paulo, Brazil, ⁵Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil
Background/Purpose: Bone mineral density(BMD) by dual X-ray absorptiometry(DXA) is currently standard clinical tool for predicting osteoporotic fracture. However, DXA doesn’t allow studying abnormalities that predict different…

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