Abstracts tagged "hormones"

Abstract Number: 1078 • 2012 ACR/ARHP Annual Meeting
Prolactin Is Increased in Responders to Anti-TNFá Treatment and the Role of the Prolactin Receptor in Rheumatoid Arthritis
Man Wai Tang¹, Danielle Marie Gerlag², Veronica Codullo³, Elsa Vieira-Sousa⁴, Anne Q. Reuwer⁵, Marcel T. Twickler⁵, Robert B. M. Landewé⁶ and Paul Peter Tak⁷, ¹Division of Clinical Immunology and Rheumatology & Department of Experimental Immunology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, ²Clinical Immunology and Rheumatology, Academic Medical Center, Amsterdam, Netherlands, ³Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy, ⁴Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, ⁵Vascular Medicine, Academic Medical Center/University of Amsterdam, Amsterddam, Netherlands, ⁶Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands, ⁷Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) is the most common rheumatic disease which mainly affects women. In the last decade, it is known that prolactin (PRL) is…
Abstract Number: 678 • 2012 ACR/ARHP Annual Meeting
Estrogen Modulation of ZAS3 Is Mediated Through Estrogen Receptor α: An Underlying Mechanism of Gender-Bias in Systemic Lupus Erythematosus?
Nicholas Young¹, Alexandra Friedman², Lai-Chu Wu² and Wael N. Jarjour³, ¹Immunology and Rheumatology, The Ohio State University Medical Center, Columbus, OH, ²Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ³Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose: Global population data has indicated that post-pubertal females have decreased rates of infectious diseases when compared to male counterparts and preadolescent or postmenopausal females. …
Abstract Number: 664 • 2012 ACR/ARHP Annual Meeting
Estrogen Upregulates Interleukin-21 Production of Clusters of Differentiation 4 Positive T Lymphocytes in Patients with Systemic Lupus Erythematosus
Jennifer Lee¹, Daejun Kim¹, Jae Ho Lee¹, Seung Min Jung¹, Mi-La Cho², Seung-Ki Kwok¹, Ji Hyeon Ju¹, Kyung-Su Park¹, Sung-Hwan Park¹ and Ho-Youn Kim¹, ¹Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, South Korea, ²Rheumatism Research Center, Catholic Research Institute of Medical Science, Rheumatic research center, Catholic University of Korea, Seoul, South Korea
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease in which various organs and tissues are damaged through abnormal immune responses mediated by tissue-binding autoantibodies…
Abstract Number: 637 • 2012 ACR/ARHP Annual Meeting
Anti-Mullerian Hormone and Ovarian Reserve in Systemic Lupus Erythematosus
Chi Chiu Mok¹, Pak To Chan² and Chi Hung To², ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Medicine, Hong Kong, Hong Kong
Background/Purpose: To study the level of anti-mullerian hormone (AMH) and its relationship with age and previous cyclophosphamide (CYC) exposure in patients with systemic lupus erythematosus…
Abstract Number: 641 • 2012 ACR/ARHP Annual Meeting
Study of Anti-Müllerian Hormone and Probability of Pregnancy in 112 Systemic Lupus Erythematosus Patients Exposed or Not to Cyclophosphamide
Nathalie Morel¹, Anne Bachelot², Zeina Chakhtoura², Zahir Amoura¹, Olivier Aumaitre³, Jean-Emmanuel Kahn⁴, Du Boutin⁵, Pierre Duhaut⁶, Dominique Farge⁷, Camille Francès¹, Lionel Galicier⁸, Gaëlle Guettrot-Imbert³, Jean-Robert Harlé⁹, Olivier Lambotte¹⁰, Véronique Le Guern¹¹, Jean-Charles Piette¹², Jacques Pourrat¹³, Karim Sacre¹⁴, Damien Sene¹⁵, Salim Trad¹⁶, Elisabeth Vidal¹⁷, Lamiae Grimaldi¹⁸, Christiane Coussieu¹⁹, Nathalie Costedoat-Chalumeau²⁰ and PLUS²¹, ¹Internal Medicine, Groupe Hospitalier Pitié-Salpétrière, Paris, France, ²Endocrinology, Groupe Hospitalier Pitié-Salpétrière, Paris, France, ³Internal Medicine, Centre Hospitalier de Clermont-Ferrand, Clermont-Ferrand, France, ⁴Internal Medicine, Foch Hospital, Suresnes, France, ⁵Internal Medicine, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France, ⁶Internal Medicine and RECIF, CHU Nord, Amiens, France, ⁷Medicine, EBMT, Paris, France, ⁸Internal Medicine, Hopital Saint Louis, Paris, France, ⁹Internal Medicine, CHU Toulouse, Toulouse, France, ¹⁰Internal Medicine, Hopital Kremlin Bicêtre, Kremlin Bicêtre, France, ¹¹Department of Internal Medicine, Cochin Hospital, Paris, France, ¹²Internal Medicine 2, Groupe Hospitalier Pitié-Salpétrière, Paris, France, ¹³Toulouse University Hospital, University of Toulouse, Toulouse, France, ¹⁴Internal Medicine, University Paris-7, INSERM U699, APHP, Bichat Hospital, Paris, France, ¹⁵Internal Medicine, Hopital Lariboisière, Paris, France, ¹⁶Internal Medicine, Hopital Ambroise Paré, Paris, France, ¹⁷Department of Internal Medicine A, Dupuytren Hospital, Limoges University Hospital, Limoges, France, ¹⁸Société Laser, Paris, France, ¹⁹Groupe Hospitalier Pitié-Salpétrière, Paris, France, ²⁰Internal Medicine, Hopital Cochin, Paris, France, ²¹Paris, France
Background/Purpose: Cyclophosphamide (CYC), a drug commonly used in systemic lupus erythematosus (SLE), is associated with a risk of ovarian failure resulting in infertility. In the…
Abstract Number: 66 • 2012 ACR/ARHP Annual Meeting
Pre-Rheumatoid Arthritis (pre-RA) Subjects Had a Minority Excess with Clearly Low Serum Cortisol Levels and Females Had Lower Mean Androstenedione Levels Than Control (CN) Cohorts in Analysis of a Large Panel of Serum Steroids and Pituitary Hormones
Alfonse T. Masi¹, Kevin B. Elmore¹, Azeem A. Rehman¹, Jean C. Aldag¹ and Robert T. Chatterton², ¹Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, ²Obstetrics and Gynecology and Physiology, Northwestern University, Chicago, IL
Background/Purpose: Low serum DHEAS may predispose a minority of premenopausal women to RA. A comprehensive panel of serum steroids, their related product-to-precursor (P-P) ratios and…

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