Abstracts tagged "hormones and systemic lupus erythematosus (SLE)"

Abstract Number: 2415 • 2018 ACR/ARHP Annual Meeting
Increased Sperm DNA Fragmentation in Male Systemic LUPUS Erythematosus Patients
Bruno C Tiseo¹, Clovis A Silva², Eduardo Ferreira Borba³, Gabriela A Munhoz³, Miguel Srougi¹, Eloisa Bonfa⁴ and Marcello Cocuzza¹, ¹Discipline of Urology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, ²Pediatric Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, ³Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, ⁴Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Gonadal dysfunction may affect male systemic lupus erythematosus (SLE) patients. Recently, sperm DNA integrity analysis has shown better diagnostic and prognostic performance for predicting…
Abstract Number: 1451 • 2012 ACR/ARHP Annual Meeting
Estrogen Receptor Alpha Deficiency Protects Against Cognitive Defects in Murine Lupus
Melissa A. Cunningham¹, Osama S. Naga², Heather A. Boger³, Ann-Charlotte E. Granholm-Bentley³ and Gary S. Gilkeson⁴, ¹Med/Rheumatology, MUSC, Charleston, SC, ²Medicine/Rheumatology, Medical University of South Carolina, Charleston, SC, ³Neuroscience, Medical University of SC, Charleston, SC, ⁴Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC
Background/Purpose: Up to 80% of SLE patients have cognitive defects or affective disorders. The mechanism of CNS injury responsible for cognitive impairment is unknown. Anti-dsDNA…

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