Abstracts tagged "Histone Modification and systemic lupus erythematosus (SLE)"

Abstract Number: 2867 • 2016 ACR/ARHP Annual Meeting
Aberrant Epigenetic Alterations at the Promoter up-Regulate cAMP Responsive Element Modulator Alpha in CD4+ T Cells from Patients with Systemic Lupus Erythematosus
Qing Zhang¹, Huilin Zhang², Shu Ding³, Hai Long⁴, Yi Zhan², Xiangning Qiu⁴ and Qianjin Lu⁴, ¹Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, China, ²Second Xiangya Hospital, Central South University, Changsha, China, ³Department of Dermatology, The Third Xiangya Hospital of Central South University, Changsha, China, ⁴Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China
Background/Purpose: Recently, accumulating studies have documented that up-regulated cAMP responsive element modulator α (CREMα) which can inhibit IL-2 and induce IL-17A in T cells plays…

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Abstracts tagged "Histone Modification and systemic lupus erythematosus (SLE)"

Aberrant Epigenetic Alterations at the Promoter up-Regulate cAMP Responsive Element Modulator Alpha in CD4+ T Cells from Patients with Systemic Lupus Erythematosus