ACR Meeting Abstracts

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Abstracts tagged "histone acetylation and rheumatoid arthritis (RA)"

  • Abstract Number: 1448 • 2016 ACR/ARHP Annual Meeting

    Therapeutic Role of a Novel Histone Deacetylase 6 Inhibitor, CKD-M808, in Rheumatoid Arthritis

    Sehui Shon1, Ji Soo Park2, Daekwon Bae3, Nina Ha3, Young Il Choi3, Jin Kyun Park1,2, Eun Young Lee2, Eun Bong Lee2 and Yeong Wook Song1,2, 1Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Seoul National University, Seoul, Korea, The Republic of, Seoul, Korea, The Republic of, 2Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Seoul, Korea, The Republic of, 3CKD Research Institute, 315-20 Dongbaekjukjeon-daero, Yongin-si, Gyeonggido, South Korea, Gyeonggido, South Korea

    Background/Purpose:  Rheumatoid Arthritis (RA) is a chronic inflammatory autoimmune disease whose etiology is unclear. Recently, upregulated HDAC (histone deacetylase) activity has been reported in peripheral…
  • Abstract Number: 2347 • 2014 ACR/ARHP Annual Meeting

    Therapeutic Effect of a Novel Histone Deacetylase 6 Inhibitor, CKD-L, on Collagen Induced Arthritis and Peripheral Blood Mononuclear Cells from Patients with Rheumatoid Arthritis

    Bo Ram Oh1, Hyojin Lim2, Daekwon Bae2, Nina Ha2, Young il Choi2, Hyun Jung Yoo3,4, Jin Kyun Park3, Eun Young Lee5, Eun Bong Lee3 and Yeong Wook Song3,4, 1Division of Rheumatology, Department of Molecular Medicine and Biophamaceutical Sciences, BK 21 plus Graduate School of Convergence Science Technology, Colleage of Medicine, Seoul National University, Seoul, South Korea, 2Department of Pharmacology and Toxicology, CKD Research Institute, CKD Pharmaceutical Company, Seoul, South Korea, 3Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea, 4Department of Molecular Medicine and Biophamaceutical Sciences, BK 21 plus Graduate School of Convergence Science Technology, Colleage of Medicine, Seoul National University, Seoul, South Korea, 5Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea

    Background/Purpose Epigenetic regulation plays an important role in inflammatory arthritis, including rheumatoid arthritis (RA). Histone deacetylase inhibitor (HDACi) has been recently reported to have therapeutic…
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ACR Pediatric Rheumatology Symposium 2020

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