ACR Meeting Abstracts

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Abstracts tagged "Hepatitis"

  • Abstract Number: 2808 • 2013 ACR/ARHP Annual Meeting

    Favorable Outcome Of Hepatitis E Virus Infection In Patients With Inflammatory Arthritides Treated With Immunosupressants

    Hélène Bauer1, Cécile Luxembourger2, Sophie Fournier3, Alain G. Cantagrel4, Jean Marie Peron3, Anne Marie Roque Afonso5, Pascal Claudepierre6, S. Fabre7, Christophe Hudry8, Guillaume Lefevre9, Antoine Martin10, Laurent Messer11, Béatrice Pallot Prades12, Christian Roux13, Christelle Sordet14, Claire Veissier15, Daniel Wendling16, Jacques-Eric Gottenberg17 and Jean Sibilia18, 1rhumatologie, CHU de Hautepierre, Strasbourg, France, 2rhumatologie, CHU de Toulouse, Toulouse, France, 3Hépato-gastro-entérologie, CHU de Toulouse, Toulouse, France, 4Centre Hospitalier Universitaire de Toulouse, Toulouse, France, 5INSERM U785, CNR hépatites A et E, virologie hôpital Paul Brousse, Villejuif, France, 6Rheumatology, Henri Mondor Teaching Hospital, AP-HP, Créteil, France, 7Unité clinique d'immuno-rhumatologie, CHU MONTPELLIER, Montpellier, France, 8Rheumatology, Hopital Cochin, Paris, France, 9Lille University Hospital, Internal Medicine Department, Lille, France, 10Rhumatologie, Centre Hospitalier De St Brieuc, St Brieuc, France, 11Rhumatologie, Hopitaux Civils de Colmar, Colmar, France, 12Rhumatologie, CHU St Etienne, St Etienne, France, 13Rheuamtology, CHU L' Archet University Nice, Nice, France, 14Rheumatology, Strasbourg University Hospital, Strasbourg, France, 15rhumatologie, CHU de Bordeaux, Bordeaux, France, 16Rheumatology, University Hospital, Besancon, France, 17Strasbourg University Hospital, Strasbourg, France, 18Rheumatology, CHU Hautepierre, Strasbourg, France

    Background/Purpose: In inflammatory rheumatic diseases, the prevalence, clinical presentation and outcome of hepatitis E, an ubiquitous viral infection, remain unknown. We therefore addressed these issues…
  • Abstract Number: 1336 • 2013 ACR/ARHP Annual Meeting

    The Safety and Feasibility Of a Treat-To-Target Strategy Aimed At Achieving a Simplified Disease Activity Index Of ¡Ü3.3 While Administering Entecavir In Rheumatoid Arthritis Complicated By Hepatitis B Virus

    Yukitomo Urata1, Yoshihide Nakamura2,3 and Ken-ichi Furukawa4, 1Seihoku Central Hospital, United Municipalities of Tsugaru, Gosyogawara, Japan, 2Hirosaki University Graduate School of Medicine, Hirosaki, Japan, 3Orthopaedic Surgery, Seihoku Central Hospital, United Municipalities of Tsugaru, Gosyogawara, Japan, 4Pharmacology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan

    Background/Purpose: To elucidate the safety and feasibility of a treat-to-target (T2T) strategy aimed at achieving a simplified disease activity index (SDAI) of ≤3.3 while administering…
  • Abstract Number: 572 • 2013 ACR/ARHP Annual Meeting

    Immunization With Hepatitis B Vaccine Accelerates SLE-Like Disease In An Animal Model

    Nancy Agmon-Levin1, María Teresa Arango2, Shaye Kivity3, Aviva Katzav4, Boris Gilburd5, Miri Blank6,7, Juan-Manuel Anaya8, Gisele Zandman-Goddard9, Joab Chapman10 and Yehuda Shoenfeld11, 1The Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer, Israel, 2Doctoral Program in Biomedical Sciences Universidad del Rosario, Bogota, Colombia;Center for Autimmune Diseases Research – CREA, Universidad del Rosario,, Bogota, Colombia, 3Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, affliated to Sackler Faculty of Medicine, Tel-Aviv University Israel, Tel-Aviv, Israel, 4Department of. Neurology and Sagol Neuroscience Center, Sheba Medical Center,Tel-Hashomer, Ramat Gan, Israel, 5The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel, 6Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, affiliated to Sackler Medical School, Tel Aviv University, Ramat Gan, Israel, 7Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, affiliated to Sackler Faculty of Medicine,Tel Aviv University, Tel-Aviv, Tel-Aviv, Israel, 8School of Medicine and Health Sciences, Universidad del Rosario. Center for Autoimmune Diseases Research (CREA), Bogotá, Colombia, 9Internal Medicine C, Wolfson Medical Center;Sackler Faculty of Medicine, Tel-Aviv University, Holon, Israel, 10Department of. Neurology and Sagol Neuroscience Center, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel, 11The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Ramat Gan, Israel

    Background/Purpose: Hepatitis-B vaccine (HBVv) was proven to be successful and cost effective in preventing HBV infection and associated liver disease. However, in recent years concerns…
  • Abstract Number: 486 • 2013 ACR/ARHP Annual Meeting

    Safety Of Biologic Therapy In Veterans With Rheumatoid Arthritis and Chronic Hepatitis B Infection

    Jeffrey R. Curtis1, Mary J. Burton2, Shuo Yang3, Lang Chen4, Ted R. Mikuls5, Kevin L. Winthrop6 and John Baddley7, 1University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, AL, 2VA Hospital, Jackson, MS, 3Clinical Immunology/Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 5Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 6Dept of Infectious Disease, Oregon Health & Science University, Portland, OR, 7Medicine, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Among patients with rheumatoid arthritis and hepatitis B infection, the impact of biologic therapy on hepatotoxicity has received limited study. Methods: Using 1997-2011 national…
  • Abstract Number: 2094 • 2012 ACR/ARHP Annual Meeting

    Reactivation of Hepatitis B Virus in Autoimmune Disease Patients Receiving Immunosuppressive Agents

    Daisuke Kobayashi1, Satoshi Ito1, Megumi Unno1, Ichiei Narita2 and Akira Murasawa1, 1Niigata Rheumatic Center, Niigata, Japan, 2Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

    Background/Purpose: Reactivation of resolved hepatitis B in patients undergoing immunosuppressive therapy is now considered to be a complication of major clinical importance. Because this is…
  • Abstract Number: 1627 • 2012 ACR/ARHP Annual Meeting

    New Insights Into the Presentation and the Management of Hepatitis B Reactivation in Patients with Autoimmune Diseases and Inflammatory Arthritis

    Nina Droz1, Laurent Gilardin2, Patrice Cacoub Sr.3, Francis Berenbaum4, Daniel Wendling5, Bertrand Godeau6, Anne-Marie Piette7, Emmanuelle Dernis8, Mikael Ebbo9, Bruno Fautrel10, Arsène Meikinian11, Aude Rigolet12, Sophie Rivière13, Stanislas Pol14, Loic Guillevin15, Luc Mouthon16 and Benjamin Terrier17, 1Internal Medicine, Cochin Hospital, Paris, France, 2Internal Medicine, Saint Antoine Hospital, Paris, France, 3Department of Internal Medicine 2., CHU Pitié-Salpêtrière, Paris, France, 4Rheumatology, AP-HP, St Antoine Hospital, Paris, France, 5Service de Rhumatologie, Minjoz University Hospital, Besancon, France, 6Internal Medicine, University of Paris, AP-HP, Hôpital Mondor Créteil, Creteil, France, 7Internal Medicine, Foch Hospital, Suresnes, France, 8Centre Hospitalier, Le Mans, France, 9Internal Medicine, Conception Hospital, Marseille, France, 10Rheumatology / GRC08-EEMOIS, APHP-Pitie Salpetriere Hospital / UPMC, Paris, France, 11Internal Medicine, Jean Verdier Hospital, Bondy, France, 12Internal Medicine I & II, Pitie-Salpetriere Hospital, APHP, UPMC Paris VI, Paris, France, 13Internal Medicine, Lapeyronie, Montpellier, France, 14Hepatology, Cochin Hospital, Paris, France, 15Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, 16Internal Medicine, Hopital Cochin, Paris, France, 17Internal Medicine, Cochin University Hospital, Paris, France

    Background/Purpose: In patients with autoimmune diseases and inflammatory arthritis, immunosuppressive therapy may trigger Hepatitis B virus (HBV) reactivation, leading to significant morbidity and mortality. Objective.…
  • Abstract Number: 354 • 2012 ACR/ARHP Annual Meeting

    Delayed Onset of Hepatitis and/or Neutropenia in Patients with Rheumatoid Arthritis Treated with Combination Therapy of Methotrexate and Leflunomide

    Seung Won Choi1, Ji Seon Oh1, You Jae Kim2, Bon San Koo2, Min Wook So2, Yong-Gil Kim2, Chang-Keun Lee2 and Bin Yoo2, 1Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea, 2Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

    Background/Purpose: The adverse effects of combination therapy of methotrexate (MTX) and leflunomide (LEF) have been reported in many studies. Because combination of various doses of…
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