Abstracts tagged "Hepatitis C"

Abstract Number: 3228 • 2015 ACR/ARHP Annual Meeting
Sofosbuvir Plus Ribavirin for Hepatitis C Virus Associated Cryoglobulinemia Vasculitis: Vascuvaldic Study
David Saadoun¹, V Thibault², L Alric³, C Guillaud⁴, H Izzedine², M Costopoulos², L Musset², H Fontaine⁵, C Hezode⁴, S Pol⁵, T Poynard², P Cacoub² and SN SI Ahmed⁶, ¹Department of Internal Medicine and clinical Immunology. French National Reference Center for Autoimmune Diseases. DHU I2B (Inflammation, Immunotherapy and Biotherapy), UPMC, Paris VI, Hôpital Pitié Salpétrière, AP-HP, UPMC, Univ Paris 06, Paris, France, ²CHU Pitie Salpetriere, Paris, France, ³CHU Toulouse, Toulouse, France, ⁴CHU H Mondor, Creteil, France, ⁵CHU Cochin, Paris, France, ⁶CH Orleans, Orleans, France
Background/Purpose: Hepatitis C virus (HCV) is the etiologic agent for most cases of cryoglobulinemia vasculitis (Cryovas). Interferon–containing regimens are associated with important side effects and…
Abstract Number: 2855 • 2014 ACR/ARHP Annual Meeting
Efficacy and Safety of Rituximab Retreatment Regimen at Clinical Relapse in Severe Cryoglobulinemic Vasculitis
Luca Quartuccio¹, Francesca Zuliani², Patrizia Scaini³, Marco Lenzi⁴, Antonio Tavoni⁵, Marco Sebastiani⁶, Teresa Urraro⁷, Francesco Saccardo⁸, Costanza Sbreglia⁹, Pietro Pioltelli¹⁰, Paolo Fraticelli¹¹, Davide Filippini¹², Salvatore Scarpato¹³, Oreste Perrella⁹, Armando Gabrielli¹⁴, Dario Roccatello¹⁵, Anna Linda Zignego¹⁶, Clodoveo Ferri¹⁷, Stefano Bombardieri¹⁸, Maurizio Pietrogrande¹⁹, Massimo Galli²⁰, Giuseppe Monti⁸ and Salvatore De Vita¹, ¹Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy, ²Rheumatology Clinic, University Hospital of Udine, Udine, Italy, ³Nephrology, Spedali Civili di Brescia, Brescia, Italy, ⁴University of Bologna, Bologna, Italy, ⁵Rheumatology Clinic, University of Pisa, Pisa, Italy, ⁶Rheumatology Clinic, University of Modena and Reggio Emilia, Modena, Italy, ⁷Center for Systemic Manifestations of Hepatitis Viruses (MASVE), Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, ⁸Internal Medicine Unit, Saronno Hospital, Azienda Ospedaliera di Busto Arsizio, Saronno (VA), Italy, ⁹Rheumatology Unit, AO Cotugno, Naples, Italy, ¹⁰Hematology, S.Gerardo Hospital, Monza, Italy, ¹¹Istituto di Clinica Medica, Università Politecnica delle Marche, Ancona, Italy, ¹²Rheumatology Unit, Ospedale Niguarda Ca’ Granda, Milan, Italy, ¹³Rheumatology Unit, M. Scarlato Hospital, Scafati, Salerno, Italy, ¹⁴Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona, Italy, ¹⁵CORSO RAFFAELLO 30, UNIVERSITY OF TURIN (ITALY), TURIN, Italy, ¹⁶University of Florence, Center for Systemic Manifestations of Hepatitis Viruses (MASVE), Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, ¹⁷Internal Med/Rheumatology, Univ Modena Reggio Emilia, Modena, Italy, ¹⁸Rheumatology Unit, University of Pisa, Pisa, Italy, ¹⁹Internal Medicine Unit, Policlinico San Marco, Bergamo, Italy, ²⁰Istituto di Malattie Infettive e Tropicali, Università di Milano c/o Ospedale L. Sacco, Milano, Italy
Background/Purpose: Two independent controlled randomized trials recently reported the efficacy and safety of rituximab (RTX) monotherapy in severe cryoglobulinemic vasculitis (CV) (1, 2), with one…
Abstract Number: 2223 • 2014 ACR/ARHP Annual Meeting
High Prevalence of Hepatitis C Virus Infection in a Japanese Inclusion Body Myositis Cohort
Akinori Uruha¹, Satoru Noguchi², Yukiko K. Hayashi³, Ikuya Nonaka² and Ichizo Nishino², ¹Department of Clinical Development, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, Japan, ²Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, ³Department of Neurophysiology, Tokyo Medical University, Tokyo, Japan
Background/Purpose There have been several case reports of inclusion body myositis (IBM) that appeared after chronic hepatitis C virus (HCV) infection. However, the relationship between…
Abstract Number: 2184 • 2014 ACR/ARHP Annual Meeting
Selective Consumption of C2 Component in HCV Patients
Atila Granados Afonso de Faria¹, Luis Eduardo C. Andrade² and Maria Lucia Gomes Ferraz³, ¹Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ²Fleury Laboratories, Sao Paulo, Brazil, ³Internal Medicine, Gastroenterology Division, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose - Hepatitis C virus (HCV) causes immunologic disorders (vasculitis, myositis, arthritis) and high frequency of autoantibodies and mixed cryoglobulinemia (CRYO). Recently, we observed that…
Abstract Number: 2163 • 2014 ACR/ARHP Annual Meeting
Genetic Variants of TNFAIP3 in Patients with HCV Related Lymphoma Are Associated with the Presence of Rheumatoid Factor (RF)
Gaetane Nocturne¹, Saida Boudaoud², Caroline Besson³, Frederic Davi⁴, Danielle Canioni⁵, Patrice Cacoub⁶, Olivier Hermine⁷ and Xavier Mariette⁸, ¹INSERM U1012, Paris sud university, Le Kremlin Bicetre, France, ²Université Paris-Sud, INSERM U1012, Le Kremlin Bicêtre, France, ³Paris Sud University, Le Kremlin Bicêtre, France, ⁴Department of Pathology, Hôpital de la Pitié Salepetrière, Paris, France, ⁵Service d'anatomo-pathologie, Hôpital Necker,, Paris, France, ⁶Groupe Hospitalier Pitié Salpétrière, Service de Médecine Interne, DHU i2B, Paris, France, ⁷Service d'hématologie, Centre de référence des mastocytoses, Hôpital Necker Enfants malades, Université Paris V, IFR Necker,, Paris, France, ⁸rheumatology, Université Paris-Sud, Le Kremlin Bicêtre, France
Background/Purpose: HCV chronic infection is associated with an increased risk of non-Hodgkin lymphoma (NHL) occurrence. HCV-associated NHL share homologies with primary Sjögren Syndrome (pSS)-associated NHL,…
Abstract Number: 1644 • 2014 ACR/ARHP Annual Meeting
Mycophenolic Acid and Ribavirin Induces Cytoplasmic Autoimmunogenic Rods and Rings Structures in Vivo
Gerson D Keppeke Sr.¹, Eunice Nunes², Maria Lucia Ferraz³, Sandro F. Perazzio¹, Mônica Prado¹, Edward K.L. Chan⁴ and Luis Eduardo C. Andrade⁵, ¹Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, ²Gastroenterology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, ³Gastroenterology Division, Universidade Federal de São Paulo, São Paulo, Brazil, ⁴Oral Biology, University of Florida, Gainesville, FL, ⁵Fleury Laboratories, Sao Paulo, Brazil
Background/Purpose Autoantibodies to IMPDH2 occur in Hepatitis C patients receiving ribavirin (RBV) & interferon-α (IFN-α). Anti-IMPDH2 antibodies recognize “rods and rings” (RR) cytoplasmic structures in…
Abstract Number: 1372 • 2014 ACR/ARHP Annual Meeting
Prevalence of Cardiovascular Disease in US Veterans with Rheumatoid Arthritis and Hepatitis C Infection
Ruchika Patel¹, Ted R. Mikuls², J. Steuart Richards³, Grant W. Cannon⁴, Gail S. Kerr⁵, Lisa A. Davis⁶, Liron Caplan⁷ and Joshua F. Baker⁸, ¹Medicine/Rheumatology, University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA, ²Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ³Rheumatology, Washington DC VA and Georgetown University, Washington, DC, ⁴Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁵Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ⁶Denver VAMC and Univ of Colorado School of Medicine, Aurora, CO, ⁷Div of Rheumatology, Denver VA and Univ of Colorado School of Medicine, Aurora, CO, ⁸Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA
Background/Purpose: Chronic hepatitis C (HCV) and rheumatoid arthritis (RA) have both been associated with higher cardiovascular disease (CVD) in US veterans. Whether the presence of…
Abstract Number: 2811 • 2013 ACR/ARHP Annual Meeting
Disease Characteristics and Treatment Patterns In US Veterans With Rheumatoid Arthritis and Concomitant Hepatitis C Infection
Ruchika Patel¹ and Joshua Baker², ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: The prevalence of concurrent rheumatoid arthritis (RA) and hepatitis C (HCV) is estimated at 0.02%, affecting around 40,000 Americans. To our knowledge, no existing…
Abstract Number: 2637 • 2013 ACR/ARHP Annual Meeting
Validation Study Of The International Classification Criteria For The Cryoglobulinemic Vasculitis
Luca Quartuccio¹, Miriam Isola², Laura Corazza³, Soledad Retamozo⁴, Manal Abdel-Moneim El-Menyawi⁵, Elisa Gremese⁶, Marco Sebastiani⁷, Nicolo Pipitone⁸, Teresa Urraro⁹, Vincenza Conteduca¹⁰, Christos Koutsianas¹¹, Benjamin Terrier¹², Mostafa Naguib Zoheir¹³, Alessandra Ghinoi¹⁴, Davide Filippini¹⁵, Francesco Saccardo¹⁶, Mohamed Nabil Salem¹⁷, Salvatore Scarpato¹⁸, Paolo Fraticelli¹⁹, Antonio Tavoni²⁰, Eleonora Catarsi²¹, Cesare Mazzaro²², Pietro Pioltelli²³, Mervat Matar⁵, Patrizia Scaini²⁴, Matija Tomsic²⁵, Norihiro Nishimoto^26,27, Dimitrios Vassilopoulos²⁸, Michael Voulgarelis²⁹, Gaafar M. Ragab³⁰, Carlo Salvarani³¹, Armando Gabrielli³², Patrice Cacoub³³, Loic Guillevin³⁴, Domenico Sansonno³⁵, Anna Linda Zignego³⁶, Gianfranco Ferraccioli⁶, Athanasios G. Tzioufas³⁷, Manuel Ramos-Casals³⁸, Clodoveo Ferri³⁹, Maurizio Pietrogrande⁴⁰, Giuseppe Monti¹⁶, Massimo Galli⁴¹, Stefano Bombardieri⁴² and Salvatore De Vita⁴³, ¹Rheumatology Clinic, DSMB, University of Udine, Udine, Italy, ²Institute of Statistics, DSMB, University of Udine, Udine, Italy, ³Rheumatology Clinic, University of Udine, Udine, Italy, ⁴Laboratorio de Enfermedades Autoinmunes Josep Font, IDIBAPS, Hospital Clínic, Barcelona, Spain, ⁵Faculty of Medicine, Cairo, Egypt, ⁶Division of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy, ⁷Internal Medicine, University of Modena and Reggio Emilia, Modena, Italy, ⁸Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁹Center for Systemic Manifestations of Hepatitis Viruses (MASVE), Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, ¹⁰Department of Internal Medicine and Clinical Oncology, University of Bari, Bari, Italy, ¹¹Department of Pathophysiology, Medical School of Athens, Athens, Greece, ¹²Internal Medicine, Cochin University Hospital, Paris, France, ¹³Faculty of Medicine, Cairo University, Cairo, Egypt, ¹⁴Rheumatology, Arcispedale S Maria Nuova, Reggio Emilia, Italy, ¹⁵Rheumatology Unit, Ospedale Niguarda,, Milan, Italy, ¹⁶Internal Medicine Unit, Saronno Hospital, Azienda Ospedaliera di Busto Arsizio, Saronno (VA), Italy, ¹⁷Faculty of Medicine, Beni Swafe University, Beni Swafe, Egypt, ¹⁸Rheumatology Unit, M. Scarlato Hospital, Scafati, Salerno, Italy, ¹⁹Istituto di Clinica Medica, Università Politecnica delle Marche, Ancona, Italy, ²⁰University of Pisa, Immunoallergology Unit, Pisa, Italy, ²¹Department of Internal Medicine, Section of Immunoallergology, University of Pisa, Pisa, Italy, ²²Department of Internal Medicine, Pordenone General Hospital, Pordenone, Italy, ²³Hematology, S.Gerardo Hospital, Monza, Italy, ²⁴Nephrology, Spedali Civili di Brescia, Brescia, Italy, ²⁵Department of Rheumatology, University Medical Centre Ljubjana, Ljubljana, Slovenia, ²⁶Laboratory of Immune Regulation, Wakayama Medical University, Ibaraki, Japan, ²⁷Osaka Rheumatology Clinic, Osaka, Japan, ²⁸2nd Department of Medicine, Athens University School of Medicine, Athens, Greece, ²⁹School of Medicine, University, Department of Pathophysiology, Athens, Greece, ³⁰Int Medicine Hosp/Rheum&Immun, Faculty of Medicine, Cairo University, Giza, Egypt, ³¹Rheumatology, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, ³²Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona, Italy, ³³Médecine Interne 2, Hopital Pitié-Salpétrière, Paris, France, ³⁴Internal Medicine, Division of Internal Medicine, Hôpital Cochin, University Paris Descartes, Paris, France, ³⁵Section of Internal Medicine and Clinical Oncology, Department of Biomedical Sciences and Human Oncology, University of Bari, Medical School, Bari, Italy, ³⁶University of Florence, Center for Systemic Manifestations of Hepatitis Viruses (MASVE), Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, ³⁷Pathophysiology, School of Medicine, National University of Athens, Athens, Greece, ³⁸Laboratorio de Enfermedades Autoinmunes Josep Font, Hospital Clínic, Barcelona, Spain, ³⁹Department of Internal Medicine, University of Modena and Reggio Emilia, Modena, Italy, ⁴⁰Internal Medicine Unit, Policlinico San Marco, Bergamo, Italy, ⁴¹Istituto di Malattie Infettive e Tropicali, Università di Milano c/o Ospedale L. Sacco, Milano, Italy, ⁴²Department of Clinical and Experimental Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy, ⁴³Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy
Background/Purpose: preliminary Classification Criteria for cryoglobulinemic vasculitis (CV) have been developed in 2011 by an European cooperative study, with an adequate methodology in a large…

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