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Abstracts tagged "heat-shock proteins and Idiopathic Inflammatory Myopathies (IIM)"

  • Abstract Number: 1297 • ACR/ARP Annual Meeting 2019

    Increased Hsp90 in Plasma and Muscle Tissue Associates with Disease Activity and Skeletal Muscle Involvement in Idiopathic Inflammatory Myopathies

    Hana Storkanova1, Sabina Oreska 2, Maja Spiritovic 3, Barbora Hermankova 4, Olga Kryštůfková 1, Herman Mann 2, Martin Komarc 5, Josef Zamecnik 6, Karel Pavelka 2, Jiri Vencovsky 1, Ladislav Senolt 2 and Michal Tomcik 2, 1Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague, Czech Republic, 2Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, 3Faculty of Physical Education and Sport, Department of Physiotherapy, Charles University, Prague, Czech Republic, Prague 2, Hlavni mesto Praha, Czech Republic, 4Faculty of Physical Education and Sport, Department of Physiotherapy, Charles University, Prague, Czech Republic, Prague, Czech Republic, 5Department of Methodology, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, 65Department of Pathology and Molecular Medicine, 2nd Medical School and University Hospital Motol, Charles University, Prague, Czech Republic, Prague, Czech Republic

    Background/Purpose: Heat shock proteins (Hsps) are chaperones playing important roles in skeletal muscle physiology, adaptation to exercise or stress, and activation of inflammatory cells.The aim…

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