Abstracts tagged "heat-shock proteins and Idiopathic Inflammatory Myopathies (IIM)"

Abstract Number: 1297 • 2019 ACR/ARP Annual Meeting
Increased Hsp90 in Plasma and Muscle Tissue Associates with Disease Activity and Skeletal Muscle Involvement in Idiopathic Inflammatory Myopathies
Hana Storkanova¹, Sabina Oreska ², Maja Spiritovic ³, Barbora Hermankova ⁴, Olga Kryštůfková ¹, Herman Mann ², Martin Komarc ⁵, Josef Zamecnik ⁶, Karel Pavelka ², Jiri Vencovsky ¹, Ladislav Senolt ² and Michal Tomcik ², ¹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague, Czech Republic, ²Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, ³Faculty of Physical Education and Sport, Department of Physiotherapy, Charles University, Prague, Czech Republic, Prague 2, Hlavni mesto Praha, Czech Republic, ⁴Faculty of Physical Education and Sport, Department of Physiotherapy, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁵Department of Methodology, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁶5Department of Pathology and Molecular Medicine, 2nd Medical School and University Hospital Motol, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Heat shock proteins (Hsps) are chaperones playing important roles in skeletal muscle physiology, adaptation to exercise or stress, and activation of inflammatory cells.The aim…

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