Abstracts tagged "hand"

Abstract Number: 1274 • ACR Convergence 2023
Rheumatoid Arthritis Patients, Achieving Low Disease Activity State or Remission, Still Demonstrate Significant Hand Disability, as Assessed by Functional Dexterity Test: A Disconnection Between CDAI and Functional Hand Assessment
Aniela Shouval¹, Amihai Levkovitch², Itzhak Rosner³, shiri keret⁴, Irina Rokhyan², Boris Tchalabian², Esther Hof⁵ and Gleb Slobodin⁶, ¹Bnai Zion Medical Center, Haifa, Israel, ²Department of Rehabilitation, Bnai Zion Medical Center, Haifa, Israel, ³Bnai Zion Medical Center/Technion, Haifa, Israel, ⁴Bnai Zion, Atlit, Israel, ⁵Occupational Therapy Unit, Bnai zion Medical Center, Haifa, Israel, ⁶Rheumatology Unit, Bnai Zion Medical Center, Haifa, Israel
Background/Purpose: Direct functionality of the hand is not commonly assessed in daily practice or clinical trials in patients with rheumatoid arthritis (RA). Functional dexterity test…
Abstract Number: 1593 • ACR Convergence 2023
Combining Single-cell RNA Sequencing and Population-based Studies Reveals Hand Osteoarthritis-associated Chondrocyte Subpopulations and Pathways
Hui Li¹, Xiaofeng Jiang¹, Yongbing Xiao¹, Yuqing Zhang², Weiya Zhang³, Michael Doherty³, Jacquelyn Nestor⁴, Changjun Li⁵, Jing Ye¹, Tingting Sha⁶, Houchen Lyu¹, Jie Wei⁷, Chao Zeng¹ and Guanghua Lei¹, ¹Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China, ²Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, ³Academic Rheumatology, Clinical Sciences Building, University of Nottingham, City Hospital, Nottingham, United Kingdom, ⁴Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China, ⁶Hunan Key Laboratory of Joint Degeneration and Injury, Changsha, China, ⁷Health Management Center, Xiangya Hospital Central South University, Changsha, China
Background/Purpose: Hand osteoarthritis (OA) is a common heterogeneous joint disorder with differences in etiology and pathophysiology from the large weight-bearing knee or hip OA. Its…
Abstract Number: 1981 • ACR Convergence 2023
The Association Between X-ray Progression and Clinical Outcomes in Patients with Hand Osteoarthritis with 5-year Follow-up
Olga Sleglova¹, Jiri Baloun², Jindriska Gatterova¹, Xiao Svec¹, Olga Ruzickova¹, Karel Pavelka³ and Ladislav Senolt⁴, ¹Rheumatology Institute, Prague, Czech Republic, ²Institute of Rheumatology, Prague, Czech Republic, ³Institut of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Praha, Czech Republic, ⁴Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Praha, Czech Republic
Background/Purpose: Hand osteoarthritis (HOA) is a heterogeneous disorder with two main subtypes, non-erosive and erosive. The progression of HOA is assessed by various radiographic scoring…
Abstract Number: 1983 • ACR Convergence 2023
Heated Mittens for Patients with Hand Osteoarthritis: A Randomized Trial
Cecilie Bartholdy¹, Anna Døssing², Zara Stisen¹, Sabrina Mai Nielsen³, Henning Bliddal¹, Robin Christensen⁴, Marius Henriksen¹ and Karen Ellegaard¹, ¹The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark, ²The Parker Institutte, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark, ³The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, ⁴Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark
Background/Purpose: Hand Osteoarthritis (OA) is common and causes pain and disability. Heat is anecdotally known to moderate symptoms and is conditionally recommended as a treatment…
Abstract Number: 2231 • ACR Convergence 2023
Ixekizumab Significantly Improves Nail Disease and Adjacent Joint Tenderness and Swelling in Psoriatic Arthritis
Dennis McGonagle¹, Arthur Kavanaugh², Iain McInnes³, Lars Erik⁴, Joseph Merola⁵, Bruce Strober⁶, Rebecca Bolce⁷, Jeffrey Lisse⁷, Jennifer Pustizzi⁷, Christophe Sapin⁷ and Christopher T Ritchlin⁸, ¹Leeds Teaching Hospitals NHS Trust, Academic Unit for the Musculoskeletal Diseases, Leeds, United Kingdom, ²Division of Rheumatology, Allergy, and Immunology, University of California San Diego, La Jolla, CA, ³University of Glasgow, Glasgow, United Kingdom, ⁴Bispebjerg-Frederiksberg Hospital, Vedbæk, Denmark, ⁵Harvard Medical School, Brigham and Women's Hospital, Newton, MA, ⁶Yale University, New Haven, CT, ⁷Eli Lilly and Company, Indianapolis, IN, ⁸University of Rochester Medical School, Allergy, Immunology & Rheumatology Division, Canandaigua, NY
Background/Purpose: Nail psoriasis (PsO) is a strong predictor for the development of psoriatic arthritis (PsA) and has been reported in 63–83% of patients with PsA1.…
Abstract Number: 2354 • ACR Convergence 2023
Is Midkine a Novel Biomarker for Acro-osteolysis in Systemic Sclerosis?
Ganiat Adeogun¹, Venkateswara Gogulamudi², Meridith Balbach¹, Anthony Donato² and Tracy Frech¹, ¹Vanderbilt University Medical Center, Nashville, TN, ²Salt Lake Veterans Affairs Medical Center, Salt Lake City, UT
Background/Purpose: Acro-osteolysis is a hand complication in systemic sclerosis (SSc) characterized by the destruction of distal digital bone possibly related to repetitive ischemia-reperfusion injury. Diagnosis…
Abstract Number: 1904 • ACR Convergence 2022
Is Treating Painful Hand Osteoarthritis with Hormone Replacement Therapy Feasible? Primary Results from a Randomised Controlled Trial in Post-menopausal Women
Jennifer Williams¹, Mae Chester-Jones¹, Megan Goff², Anne Francis¹, Gretchen Brewer¹, Ioana Marian¹, Malvika Gulati¹, Charles Mackworth-Young³, Victoria Glover⁴, Sarah Lamb¹, Tonia Vincent⁵, Katy Vincent¹, Susan Dutton¹ and Fiona Watt⁶, ¹University of Oxford, Oxford, United Kingdom, ²University of Oxford, London, United Kingdom, ³Imperial College Healthcare NHS Trust, London, United Kingdom, ⁴White Horse Medical Practice, Faringdon, United Kingdom, ⁵Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, ⁶Imperial College London, London, United Kingdom
Background/Purpose: Hand osteoarthritis (OA) is more common in females and relative risk increases further around the age of menopause, potentially implicating sex hormone deficiency. There…
Abstract Number: 2204 • ACR Convergence 2022
Interosseous Tendon Inflammation in the Hands: A Novel Feature of Developing Rheumatoid Arthritis? Results from a Large MRI Study in Clinically Suspect Arthralgia
Bastiaan van Dijk¹, Hanna van Steenbergen¹, Monique Reijnierse², Sarah J.H. Khidir², Lambertus Wisse¹, Marco deRuiter¹ and Annette van der Helm-van Mil³, ¹Leiden University Medical Centre (LUMC), Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Leiden University Medical Center, Erasmus Medical Center, Leiden, Netherlands
Background/Purpose: Inflammation around the tendons of hand interosseous muscles (interosseous tendon inflammation; ITI) on MRI was recently reported for the first time in rheumatoid arthritis…
Abstract Number: 0023 • ACR Convergence 2022
New Biomarkers in Hand Osteoarthritis: The Micro-RNA Signature
Maxime Auroux¹, Marjorie Millet², Blandine Merle², Elisabeth Fontanges¹, Florence Duvert¹, Evelyne Gineyts³, Jean-Charles Rousseau³, Olivier Borel², Alexandre Mercier¹, Eric LESPESSAILLES⁴ and Roland Chapurlat¹, ¹Hospices Civils de Lyon, LYON, France, ²INSERM U1033, LYON, France, ³INSERM 1033, Lyon, France, ⁴Regional hospital centre of Orleans, France, ORLEANS, Centre, France
Background/Purpose: Hand osteoarthritis (HOA) is a highly prevalent disease, associated with important disability and socio-economic burden. Erosive HOA, almost exclusively found in women, induces more…
Abstract Number: 0215 • ACR Convergence 2022
Online Teaching of Hand Examination Using Student-recorded Videos and Remotely Delivered Feedback: A Pilot Study
Mostafa Ahmad¹, Frances Parry² and Simon Maxwell², ¹Western General Hospital, Edinburgh, Scotland, United Kingdom, ²MSc Internal Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom
Background/Purpose: Enhancing physical examination skills improves the identification of clinical findings, decision-making and overall management. Feedback is a crucial factor in achieving effective learning but…
Abstract Number: 0242 • ACR Convergence 2022
Neural Networks for Distinguishing Rheumatoid Arthritis from Psoriatic Arthritis by Using Magnetic Resonance Imaging
Lukas Folle¹, Sara Bayat², Arnd Kleyer³, Filippo Fagni², Lorenz Kapsner⁴, Maja Schlereth⁵, Timo Meinderink², Katharina Breininger⁵, Koray Tascilar³, Gerhard Kroenke³, Michael Uder⁶, MIchael Sticherling⁷, Sebastian Bickelhaupt⁴, Georg Schett⁸, Andreas Maier⁹, Frank Roemer¹⁰ and David Simon³, ¹Friedrich-Alexander-Universitaet Erlangen Nürnberg, Erlangen, Germany, ²University Hospital Erlangen; Department of Internal Medicine 3 - Rheumatology and Immunology, Erlangen, Germany, ³Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ⁴University Hospital Erlangen; Institute of Radiology, Erlangen, Germany, ⁵Friedrich-Alexander Universität Erlangen-Nürnberg, Artificial Intelligence in Medical Imaging, Erlangen, Germany, ⁶University Hospital Erlangen; Lehrstuhl für Diagnostische Radiologie, Erlangen, Germany, ⁷University Hospital Erlangen; Institute of Dermatology, Erlangen, Germany, ⁸Universitätsklinikum Erlangen, Erlangen, Germany, ⁹Friedrich-Alexander-Universität Erlangen-Nürnberg, Lehrstuhl für Mustererkennung, Erlangen, Germany, ¹⁰Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany
Background/Purpose: To evaluate (i) whether neural networks can distinguish seropositive rheumatoid arthritis (RA+), seronegative RA (RA-), and psoriatic arthritis (PsA) using MRI data based on…
Abstract Number: 1223 • ACR Convergence 2022
Autoimmune Thyroid Disease Associates with Hand Pain in Older Adults in the Third National Health and Nutrition Examination Survey
Clement Tagoe¹ and Wanyi Wang², ¹Albert Einstein College of Medicine, Bronx, NY, ²Elite Research, LLC, Irving, TX
Background/Purpose: Chronic hand pain is a prominent symptom of many forms of arthritis and autoimmune disease. It is often the initial presentation of diseases marked…
Abstract Number: 1252 • ACR Convergence 2022
Interrater Agreement of Hand Ultrasounds in Inflammatory Arthritis
Annie H Yang¹, Norman Madsen², Bethany Marston¹, Brian H. Nathanson³, Darren Tabechian⁴ and Allen Anandarajah⁵, ¹University of Rochester, Rochester, NY, ²University of Rochester, NY, Rochester, NY, ³OptiStatim, LLC, Longmeadow, MA, ⁴URMC, Rochester, NY, ⁵University of Rochester, Rochester
Background/Purpose: Musculoskeletal ultrasound (US) is an imaging modality that is more sensitive in identifying synovitis due to inflammatory arthritis than clinical examination. Little is known…
Abstract Number: 1640 • ACR Convergence 2022
Tryptophan Metabolites Are Associated with Erosion and Symptoms in Hand Osteoarthritis: Results from the DIGICOD Cohort
Marie Binvignat¹, Patrick Emond², Brenda Miao³, Alice Courties⁴, Emmanuel Maheu⁵, Margreet Kloppenburg⁶, Pascal Richette⁷, Atul Butte³, Encarnita Mariotti-Ferrandiz¹, Francis Berenbaum⁸, Harry Sokol⁹ and Jérémie SELLAM¹⁰, ¹Sorbonne Universite, Paris, France, ²Tours University, Tours, France, ³UCSF, San Francisco, CA, ⁴Service de Rhumatologie, AP-HP Hopital Saint-Antoine, Sorbonne Universite, INSERM, Centre de Recherche Saint-Antoine, Paris, France, Paris, France, ⁵Hopital Paris Saint Antoine, Moirans, Auvergne-Rhone-Alpes, France, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France, ⁸Sorbonne University - Saint-Antoine hospital, Paris, France, ⁹Sorbonne Universite Saint Antoine Hospital, Paris, France, ¹⁰Sorbonne Universite, AP-HP, Saint-Antoine hospital, Paris, France
Background/Purpose: Tryptophan (Trp) and its metabolites have been linked to inflammatory processes and associated with gut dysbiosis. However, their role in osteoarthritis (OA) is unknown.…
Abstract Number: 1641 • ACR Convergence 2022
Determination and Characterization of Patient Subgroups with Different Pain Progression in Hand Osteoarthritis
Coen van der Meulen¹, Lotte van de Stadt¹, Frits Rosendaal¹, Jos Runhaar² and Margreet Kloppenburg¹, ¹Leiden university medical center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Pain is central to hand osteoarthritis (OA). Previous studies reported stable mean pain levels on the short to midterm. Subgroups with different pain trajectories…

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