Abstracts tagged "hand"

Abstract Number: 2472 • ACR Convergence 2023
Synovitis and the Risk of Incident Hand Osteoarthritis: Data from the Xiangya Osteoarthritis Study
ting Jiang¹, Qianlin Weng¹, Jiatian Li², Yuqing Zhang³, Weiya Zhang⁴, Michael Doherty⁴, Tuo Yang⁵, Zidan Yang⁶, Ke Liu¹, Qiu Chen¹, Jie Wei⁷, Guanghua Lei² and Chao Zeng², ¹Xiangya Hospital, Central South University, Changsha, China, ²Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China, ³Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, ⁴Academic Rheumatology, Clinical Sciences Building, University of Nottingham, City Hospital, Nottingham, United Kingdom, ⁵Department of Health Management Center, Xiangya Hospital, Central South University, Changsha, China, ⁶Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, China, ⁷Health Management Center, Xiangya Hospital Central South University, Changsha, China
Background/Purpose: Synovitis is a modifiable pathological lesion of hand osteoarthritis (HOA). Although synovitis has been related to the prevalence and symptoms of HOA, it remains…
Abstract Number: 0481 • ACR Convergence 2023
Automatically Detect Finger Joint Center and Angle on Hand X-ray: A Deep Learning Model
Yuan Gao¹, Juan Shan², Raj Ponnusamy², Jordan Blackadar³, Carmine Guida², Jeffrey Driban⁴, Timothy McAlindon⁵ and Ming Zhang¹, ¹Boston University, Boston, MA, ²Pace University, New York, NY, ³Photo Diagnostic System, Boston, MA, ⁴Tufts Medical Center, Boston, MA, ⁵Tufts Medical Center, Arlington, MA
Background/Purpose: Hand osteoarthritis (OA) is the second most common anatomic region for OA. The diagnosis and evaluation of hand OA heavily rely on subjective assessments…
Abstract Number: 1035 • ACR Convergence 2023
Diagnostic and Educational Utility of an Ultrasound Protocol for Evaluation of Hand Pain in Systemic Sclerosis
Meridith Balbach, Tracy Frech, Nicholson Chadwick, Kevin Byram and Erin Chew, Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Hand impairment is a prevalent issue among systemic sclerosis (SSc) patients and contributes to disability and diminished quality of life. Managing hand pain can…
Abstract Number: 1147 • ACR Convergence 2023
Blood-Based Biomarkers of Inflammation and Tissue Remodeling Can Discriminate Between Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis and Are Associated with Hand Function
Helena Port I Linares¹, Birte Coppers², Sara Bayat², Godonou Elie-Tino², Larissa Valor-Mendez², David Simon², Filippo Fagni², Giulia Corte², Anne-Christine Bay-Jensen³, Koray Tascilar², Axel Hueber⁴, Verena Schoenau², Michael Sticherling⁵, Simon Heinrich⁶, Daniela Bohr², Georg Schett⁷, Arnd Kleyer⁸, Sigrid Leyendecker⁶, Signe Holm Nielsen³ and Anna-Maria Liphardt⁹, ¹Nordic Bioscience A/S / University of Copenhagen, Copenhagen, Denmark, ²Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology / Deutsches Zentrum Immuntherapie, Erlangen, Germany, ³Nordic Bioscience, Herlev, Denmark, ⁴Division of Rheumatology, Klinikum Nürnberg, Paracelsus Medical University / Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology, Nürnberg, Germany, ⁵Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Dermatology, Erlangen, Germany, ⁶Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Institute of Applied Dynamics, Erlangen, Germany, ⁷Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, ⁸University Hospital Erlangen, Erlangen, Germany, ⁹Friedrich-Alexander-University Erlangen-Nuremberg, Internal Medicine 3 - Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany
Background/Purpose: Inflammatory musculoskeletal diseases including rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are characterized by physical function impairment due to progressive inflammatory and structural changes.…
Abstract Number: 1185 • ACR Convergence 2023
Soluble Buffered Alendronate After Denosumab Discontinuation in Erosive Hand OA Patients
Tine Vanhaverbeke¹, Dirk Elewaut² and Ruth Wittoek¹, ¹Dept. of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium, ²Ghent University and VIB Center for Inflammation Research, Ghent, Belgium
Background/Purpose: In osteoporotic patients, discontinuation of denosumab is associated with a rapid increase in bone turnover and bone loss. Denosumab was recently proven to have…
Abstract Number: 1186 • ACR Convergence 2023
Presence of Erosions Is Not a Risk Factor for the Development of Knee OA in a Hand OA Population: The Framingham OA Study
Tine Vanhaverbeke¹, Gabriela Rabasa², Ruth Wittoek¹, Ida Kristin Haugen³ and David Felson², ¹Dept. of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium, ²Boston University, Boston, MA, ³Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Osteoarthritis (OA) is a prevalent musculoskeletal disease and can affect multiple joint sites in one patient. Studies have shown an association between hand and…
Abstract Number: 0023 • ACR Convergence 2022
New Biomarkers in Hand Osteoarthritis: The Micro-RNA Signature
Maxime Auroux¹, Marjorie Millet², Blandine Merle², Elisabeth Fontanges¹, Florence Duvert¹, Evelyne Gineyts³, Jean-Charles Rousseau³, Olivier Borel², Alexandre Mercier¹, Eric LESPESSAILLES⁴ and Roland Chapurlat¹, ¹Hospices Civils de Lyon, LYON, France, ²INSERM U1033, LYON, France, ³INSERM 1033, Lyon, France, ⁴Regional hospital centre of Orleans, France, ORLEANS, Centre, France
Background/Purpose: Hand osteoarthritis (HOA) is a highly prevalent disease, associated with important disability and socio-economic burden. Erosive HOA, almost exclusively found in women, induces more…
Abstract Number: 0215 • ACR Convergence 2022
Online Teaching of Hand Examination Using Student-recorded Videos and Remotely Delivered Feedback: A Pilot Study
Mostafa Ahmad¹, Frances Parry² and Simon Maxwell², ¹Western General Hospital, Edinburgh, Scotland, United Kingdom, ²MSc Internal Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom
Background/Purpose: Enhancing physical examination skills improves the identification of clinical findings, decision-making and overall management. Feedback is a crucial factor in achieving effective learning but…
Abstract Number: 0242 • ACR Convergence 2022
Neural Networks for Distinguishing Rheumatoid Arthritis from Psoriatic Arthritis by Using Magnetic Resonance Imaging
Lukas Folle¹, Sara Bayat², Arnd Kleyer³, Filippo Fagni², Lorenz Kapsner⁴, Maja Schlereth⁵, Timo Meinderink², Katharina Breininger⁵, Koray Tascilar³, Gerhard Kroenke³, Michael Uder⁶, MIchael Sticherling⁷, Sebastian Bickelhaupt⁴, Georg Schett⁸, Andreas Maier⁹, Frank Roemer¹⁰ and David Simon³, ¹Friedrich-Alexander-Universitaet Erlangen Nürnberg, Erlangen, Germany, ²University Hospital Erlangen; Department of Internal Medicine 3 - Rheumatology and Immunology, Erlangen, Germany, ³Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ⁴University Hospital Erlangen; Institute of Radiology, Erlangen, Germany, ⁵Friedrich-Alexander Universität Erlangen-Nürnberg, Artificial Intelligence in Medical Imaging, Erlangen, Germany, ⁶University Hospital Erlangen; Lehrstuhl für Diagnostische Radiologie, Erlangen, Germany, ⁷University Hospital Erlangen; Institute of Dermatology, Erlangen, Germany, ⁸Universitätsklinikum Erlangen, Erlangen, Germany, ⁹Friedrich-Alexander-Universität Erlangen-Nürnberg, Lehrstuhl für Mustererkennung, Erlangen, Germany, ¹⁰Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany
Background/Purpose: To evaluate (i) whether neural networks can distinguish seropositive rheumatoid arthritis (RA+), seronegative RA (RA-), and psoriatic arthritis (PsA) using MRI data based on…
Abstract Number: 1223 • ACR Convergence 2022
Autoimmune Thyroid Disease Associates with Hand Pain in Older Adults in the Third National Health and Nutrition Examination Survey
Clement Tagoe¹ and Wanyi Wang², ¹Albert Einstein College of Medicine, Bronx, NY, ²Elite Research, LLC, Irving, TX
Background/Purpose: Chronic hand pain is a prominent symptom of many forms of arthritis and autoimmune disease. It is often the initial presentation of diseases marked…
Abstract Number: 1252 • ACR Convergence 2022
Interrater Agreement of Hand Ultrasounds in Inflammatory Arthritis
Annie H Yang¹, Norman Madsen², Bethany Marston¹, Brian H. Nathanson³, Darren Tabechian⁴ and Allen Anandarajah⁵, ¹University of Rochester, Rochester, NY, ²University of Rochester, NY, Rochester, NY, ³OptiStatim, LLC, Longmeadow, MA, ⁴URMC, Rochester, NY, ⁵University of Rochester, Rochester
Background/Purpose: Musculoskeletal ultrasound (US) is an imaging modality that is more sensitive in identifying synovitis due to inflammatory arthritis than clinical examination. Little is known…
Abstract Number: 1640 • ACR Convergence 2022
Tryptophan Metabolites Are Associated with Erosion and Symptoms in Hand Osteoarthritis: Results from the DIGICOD Cohort
Marie Binvignat¹, Patrick Emond², Brenda Miao³, Alice Courties⁴, Emmanuel Maheu⁵, Margreet Kloppenburg⁶, Pascal Richette⁷, Atul Butte³, Encarnita Mariotti-Ferrandiz¹, Francis Berenbaum⁸, Harry Sokol⁹ and Jérémie SELLAM¹⁰, ¹Sorbonne Universite, Paris, France, ²Tours University, Tours, France, ³UCSF, San Francisco, CA, ⁴Service de Rhumatologie, AP-HP Hopital Saint-Antoine, Sorbonne Universite, INSERM, Centre de Recherche Saint-Antoine, Paris, France, Paris, France, ⁵Hopital Paris Saint Antoine, Moirans, Auvergne-Rhone-Alpes, France, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France, ⁸Sorbonne University - Saint-Antoine hospital, Paris, France, ⁹Sorbonne Universite Saint Antoine Hospital, Paris, France, ¹⁰Sorbonne Universite, AP-HP, Saint-Antoine hospital, Paris, France
Background/Purpose: Tryptophan (Trp) and its metabolites have been linked to inflammatory processes and associated with gut dysbiosis. However, their role in osteoarthritis (OA) is unknown.…
Abstract Number: 1641 • ACR Convergence 2022
Determination and Characterization of Patient Subgroups with Different Pain Progression in Hand Osteoarthritis
Coen van der Meulen¹, Lotte van de Stadt¹, Frits Rosendaal¹, Jos Runhaar² and Margreet Kloppenburg¹, ¹Leiden university medical center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Pain is central to hand osteoarthritis (OA). Previous studies reported stable mean pain levels on the short to midterm. Subgroups with different pain trajectories…
Abstract Number: 1903 • ACR Convergence 2022
Does Pain Sensitization by Pressure Pain Thresholds and Temporal Summation Predict Persistent Pain in Persons with Hand OA?
Pernille Steen Pettersen¹, Tuhina Neogi², Elisabeth Mulrooney¹, Marthe Gløersen¹, Hilde Berner Hammer³ and Ida K. Haugen¹, ¹Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, ²Boston University School of Medicine, Boston, MA, ³Diakonhjemmet hospital, Jar, Norway
Background/Purpose: Pain sensitization is part of the complexity of osteoarthritis (OA) pain. We aimed to examine whether pain sensitization by pressure pain thresholds (PPT) and…
Abstract Number: 1904 • ACR Convergence 2022
Is Treating Painful Hand Osteoarthritis with Hormone Replacement Therapy Feasible? Primary Results from a Randomised Controlled Trial in Post-menopausal Women
Jennifer Williams¹, Mae Chester-Jones¹, Megan Goff², Anne Francis¹, Gretchen Brewer¹, Ioana Marian¹, Malvika Gulati¹, Charles Mackworth-Young³, Victoria Glover⁴, Sarah Lamb¹, Tonia Vincent⁵, Katy Vincent¹, Susan Dutton¹ and Fiona Watt⁶, ¹University of Oxford, Oxford, United Kingdom, ²University of Oxford, London, United Kingdom, ³Imperial College Healthcare NHS Trust, London, United Kingdom, ⁴White Horse Medical Practice, Faringdon, United Kingdom, ⁵Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, ⁶Imperial College London, London, United Kingdom
Background/Purpose: Hand osteoarthritis (OA) is more common in females and relative risk increases further around the age of menopause, potentially implicating sex hormone deficiency. There…

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