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Abstracts tagged "gout and inflammatory arthritis"

  • Abstract Number: 217 • ACR/ARHP Annual Meeting 2015

    Circulating Levels of Neo-Epitopes Reflecting Connective Tissue Turnover As Biomarkers of Gout and Frequent Gout Attacks in Men

    Ana Valdes1, Tina Manon-Jensen2, Wendy Jenkins3, Anne Sofie Siebuhr4, Morten Asser Karsdal4, Sally Doherty5, Abhishek Abhishek3, Helen Richardson3, Weiya Zhang6, Michael Doherty7 and Anne C. Bay-Jensen8, 1Division of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Nottingham, United Kingdom, 2Antibody Research Unit, Nordic Bioscience, 2370, Denmark, 3Devision of Rheumatology, University of Nottingham, NG5 1PB, England, 4Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, 5Division of ROD, University of Nottingham, Nottingham, United Kingdom, 6Academic Rheumatology, School of Clinical Sciences, University of Nottingham, Nottingham, United Kingdom, 7Academic Rheumatology, City Hospital, Nottingham, United Kingdom, 8Biomarkers and Research, Rheumatology, Nordic Bioscience, Herlev, Denmark

    Background/Purpose: Recurrent flares constitute the main clinical burden of gout. The neo-epitope blood-based biomarkers, C1M and C3M, measuring matrix metalloproteinases (MMP)-mediated connective tissue degradation, have previously…

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