Abstracts tagged "glycoproteins and rheumatoid arthritis (RA)"

Abstract Number: 986 • ACR/ARHP Annual Meeting 2018
Fucosylated Tumor Necrosis Factor α Is Expressed in Rheumatoid Arthritis Synovial Tissues and Is Involved in Monocyte Adhesion
Takeo Isozaki, Shinichiro Nishimi and Tsuyoshi Kasama, Div of Rheumatology, Showa University School of Med, Shinagawa-ku Tokyo, Japan
Background/Purpose: Glycosylation has been reported to associate with tumor invasion and metastasis. Fucosylation is involved in the biological functions of adhesion molecules and growth factor…
Abstract Number: 879 • ACR/ARHP Annual Meeting 2012
Fucosyltransferase 1 (fut1) Is Overexpressed in Rheumatoid Arthritis Synovial Tissue and Modifies Cytokine Production
Takeo Isozaki¹, Jeffrey H. Ruth², M. Asif Amin¹, Phillip L. Campbell¹, Steven E. Domino³, G. Kenneth Haines III⁴ and Alisa E. Koch⁵, ¹Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, ²Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, ³Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, ⁴Department of Pathology, Yale University, New Haven, CT, ⁵Internal Medicine - Rheumatology, University of Michigan Medical School, Ann Arbor, MI
Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammation and joint destruction. Angiogenesis and cytokine production are involved in the pathogenesis of…