ACR Meeting Abstracts

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Abstracts tagged "glucocorticoids"

  • Abstract Number: 1126 • ACR Convergence 2024

    The Outcomes of Carpal Tunnel Injections and Carpal Tunnel Surgery

    wilmer sibbitt1, dihowm Fatma1, N. SUZANNE Emil1, Maheswari Muruganandam2, Roderick A Fields1, Vangala Adarsh1, Frank O'Sullivan3, Shuhei Hattori4, Frank M Delgado1 and Krystle Tapia1, 1UNM, Albuquerque, NM, 2University of New Mexico, Albuquerque, NM, 3University of New Mexico School of Medicine, Albuquerque, NM, 4University of Hawaii, Hawaii

    Background/Purpose: arpal tunnel syndrome (CTS) is the most common peripheral neuropathy secondary to chronic median nerve compression at the wrist within the space-limited carpal tunnel…
  • Abstract Number: 1983 • ACR Convergence 2024

    Immune Checkpoint Inhibitor Associated Vasculitis and Polymyalgia Rheumatica: A Systematic Review

    Aaron Teel1, Adrian Grebowicz2, Mats Junek3, Stephanie Garner4, Tom Appleton5 and Faiza Khokhar6, 1London Health Sciences Centre, Sarnia, ON, Canada, 2Western University, London, ON, Canada, 3McMaster University, Hamilton, ON, Canada, 4University of Calgary, Calgary, AB, Canada, 5The University of Western Ontario, London, ON, Canada, 6McMaster University, St. Joseph's Hamilton, Mississauga, ON, Canada

    Background/Purpose: Immune checkpoint inhibitors (ICIs) are a class of cancer immunotherapy that have been associated with immune-related adverse events (irAEs). These include multiple rheumatic diseases…
  • Abstract Number: 2435 • ACR Convergence 2024

    Attainment of Remission, Use of Immunomodulatory/suppressive Agents and Gradual Dose Tapering May Facilitate Flare-free Withdrawal of Glucocorticoids in Patients with Systemic Lupus Erythematosus

    Spyridon Katechis1, Sofia Pitsigavdaki2, Myrto Nikoloudaki2, Panagiotis Garantziotis3, Ettore Silvagni4, Argyro Repa2, Antonio Marangoni5, Irini Flouri6, Nestor Avgoustidis7, Konstantinos Parperis8, Marcello Govoni5, Prodromos Sidiropoulos9, Dimitrios Boumpas10, Antonios Fanouriakis1, George Bertsias2 and Alessandra Bortoluzzi5, 1Rheumatology and Clinical Immunology Unit, 4th Department of Internal Medicine, Attikon University Hospital, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece, Athens, Greece, 2Rheumatology and Clinical Immunology, University of Crete School of Medicine, Heraklion, Greece, Heraklion, Greece, 3Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, Erlangen, Germany, 4Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S.Anna, Ferrara, Italy, Ferrara, 5Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S.Anna, Ferrara, Italy, Ferrara, Italy, 6Rheumatology and Clinical Immunology, University of Crete School of Medicine, Heraklion, Greece, Heraklio, Crete, Greece, 7University Hospital, Rheumatology and Clinical Immunology,, Heraklion, Greece, 8University of Cyprus Medical School, Nicosia, Cyprus, 9University of Crete, Laboratory of Rheumatology, Autoimmunity and Inflammation. University Hospital, Rheumatology, Clinical Immunology. Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece, HERAKLIO, Greece, 104th Department of Internal Medicine, "Attikon" University Hospital, Athens, Greece, Athens, Greece

    Background/Purpose: For patients with SLE who are treated with glucocorticoids (GC), discontinuation of the latter is an important goal. However, the clinical conditions under which…
  • Abstract Number: 1246 • ACR Convergence 2024

    Long-Term Outcomes Based on the Sex of the Rheumatologist in a Prospective Cohort of RA Patients Receiving Biological Therapies

    Alessandro Giollo1, Mariangela Salvato2, Margherita Zen3 and doria Andrea4, 1Azienda Ospedale Università Padova, Padova, Padua, Italy, 2University of Padua, Padova, Italy, 3University of Padova, Padova, Padua, Italy, 4University of Padova, Padova, Italy

    Background/Purpose: To explore the influence of the rheumatologist's sex on long-term outcomes in patients with rheumatoid arthritis (RA) undergoing biologic therapy.Methods: This is a prospective,…
  • Abstract Number: 1989 • ACR Convergence 2024

    Higher Early Cumulative Glucocorticoid Exposure Is Associated with Worse Progression-Free Survival in Patients with Immune Checkpoint Inhibitor Inflammatory Arthritis

    Minerva Nong1, Deanna Jannat-Khah2, Karmela Kim Chan2, Nilasha Ghosh3 and Anne Bass4, 1Hospital for Special Surgery, Tampa, FL, 2Hospital For Special Surgery, New York, NY, 3Hospital for Special Surgery, New York, NY, 4Hospital for Special Surgery, Weill Cornell Medicine, New York, NY

    Background/Purpose: Although immune checkpoint inhibitors (ICI) have transformed cancer treatment, they unleash a range of immune-related adverse events (irAE), including inflammatory arthritis (ICI-IA). Glucocorticoids are…
  • Abstract Number: 2438 • ACR Convergence 2024

    Reduction in Oral Corticosteroid Use During Anifrolumab Therapy: Observations from a Real-world Cohort of Adults with Systemic Lupus Erythematosus

    Vasileios Kyttaris1, Gelareh Atefi2, Dan Persons3, Dana Withrow3 and Mawuena Binka4, 1BIDMC, Boston, MA, 2AstraZeneca, Media, PA, 3Trio Health, Louisville, CO, USA, Louisville, 4BioPharmaceuticals Medical, AstraZeneca, Wilmington, DE

    Background/Purpose: Oral corticosteroids (OCS) are a mainstay in the clinical management of systemic lupus erythematosus (SLE). However, prolonged use may result in systemic side effects.1…
  • Abstract Number: 1273 • ACR Convergence 2024

    An Investigation of Traumatic Events and Mental Health in cSLE

    Paris Moaf1, Ashley Danguecan2, Michelle Quilter3, Julie Couture4, Daniela Dominguez5, Lawrence Ng6, Asha Jeyanathan7, Reva Schachter8, Daphne Korczak9, Deborah Levy6, Linda Hiraki6 and Andrea Knight10, 1The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 2The Hospital for Sick Children, Department of Psychology, University of Toronto, Toronto, ON, Canada, 3Whyteman’s Brae Hospital, Kirkcaldy, United Kingdom, 4Centre mère-enfant Soleil du CHU de Québec, Québec, Canada, 5The Hospital for Sick Children, Toronto, Canada, 6The Hospital for Sick Children, Toronto, ON, Canada, 7The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Neurosciences and Mental Health, Research Institute, Toronto, ON, Canada, 8Sickkids Toronto, Toronto, ON, Canada, 9Hospital for Sick Children, University of toronto, Toronto, ON, Canada, 10Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with substantial morbidity, particularly in childhood-onset SLE (cSLE). Mental health conditions such as depression and…
  • Abstract Number: 1991 • ACR Convergence 2024

    Initial Corticosteroid Dosing and Effects on Disease Activity, Survival, and Tumor Progression in Immune Checkpoint Inhibitor-induced Inflammatory Arthritis

    Muhammad Bukhari1, Ami Shah2, Clifton Bingham3, Michelle Jones4 and Laura Cappelli1, 1Johns Hopkins School of Medicine, Baltimore, MD, 2Division of Rheumatology, Johns Hopkins University, Ellicott City, MD, 3Johns Hopkins University, Baltimore, MD, 4Johns Hopkins School of Medicine, Pittsburgh, PA

    Background/Purpose: Immune checkpoint inhibitor-induced inflammatory arthritis (ICI-IA) occurs in 3-7% of patients receiving ICI therapy for cancer. ICI-IA is routinely treated with corticosteroids, however, there…
  • Abstract Number: 2483 • ACR Convergence 2024

    Efficacy and Safety of Avacopan over 12 Months in Japanese Patients with MPA/GPA: A Single-center Study

    Yusuke Ushio1, Hiromi Shimada2, taichi miyagi3, Koichi Sugihara4, Mao Mizusaki5, Rina Mino5, Hayamasa yamaguchi5, Naoto Manabe5, Shusaku Nakashima2 and Hiroaki Dobashi2, 1Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, Miki, Kita District, Kagawa, Japan, 2Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan, 3Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, kidagun, Japan, 4Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, Miki-cho, Kita-gun, Kagawa Prefecture, Japan, 5Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, Miki-cho, Kita-gun, Japan

    Background/Purpose: Avacopan, an oral C5a receptor inhibitor, was demonstrated to be an alternative to glucocorticoids (GC) in the treatment of microscopic polyangiitis (MPA)/granulomatosis with polyangiitis…
  • Abstract Number: 0168 • ACR Convergence 2024

    Real-world Glucocorticoid Prescription Patterns in Patients with Lupus Nephritis: A Retrospective Study Using a Healthcare Insurance Claims Database

    Tatsuya Atsumi1, Hironari Hanaoka2, Nobuo Nishijima3, Kohji Murakami4, Mariko Nio3, Tsutomu Urakawa3, Takaaki Fujimura3 and Hiroki Hayashi5, 1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, Sapporo, Japan, 2Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 3Chugai Pharmaceutical Co., Ltd., Tokyo, Japan, 4Nippon Shinyaku Co., Ltd., Tokyo, Japan, 5Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

    Background/Purpose: Lupus nephritis (LN) is one of the most frequent organ manifestations of systemic lupus erythematosus (SLE), affecting morbidity and mortality in SLE. LN is…
  • Abstract Number: 1358 • ACR Convergence 2024

    A Step Towards Personalised Medicine – Development and Efficacy of Machine Learning Based Smart-Web Application for Prediction of Steroid Induced Hyperglycemia in Patients with Rheumatoid Arthritis and Other Autoimmune Rheumatic Diseases

    Manyam Prudhvi Krishna1, Sandeep Surendran1, MITHUN CHALAKKARAYIL BHAGAVALDAS2, Sundarakrishna Sai3, Sekhar V Easwar1, Ronith S Kumar3 and Manu Pradeep1, 1Amrita Institute of Medical Sciences, Kochi, Kerala, India, 2Amrita Institute of Medical Sciences, ERNAKULAM, Kerala, India, 3Amrita Vishwa Vidyapeetham, Kochi, Kerala, India

    Background/Purpose: Steroids play a key role in treating rheumatic diseases due to their anti-inflammatory effects. However, long-term or high-dose use leads to side effects like…
  • Abstract Number: 2027 • ACR Convergence 2024

    Clinical Features and Treatment of Retroperitoneal Fibrosis in a Referral Hospital and Literature Review

    Adrián Martín-Gutiérrez1, Javier Loricera2, Fernando Lopez-Gutierrez3 and Ricardo Blanco-Alonso4, 1Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 4Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: Retroperitoneal fibrosis (RPF) is usually idiopathic (iRPF), but may be secondary to drugs, neoplasms, infections, or may be part of an IgG4-related disease. Our…
  • Abstract Number: 2486 • ACR Convergence 2024

    Glucocorticoids May Mitigate the Risk of Avacopan-Induced Liver Dysfunction in ANCA-Associated Vasculitis: Data from a Multicenter Observational Study in Japan

    Tomohisa Uchida1, Shoichi Fukui1, Naoki Iwamoto1, Ayaka Umetsu2, Momoko Okamoto2, Keita Fujikawa2, Akinari Mizokami2, Takuya Tomokawa3, Kazusato Hara3, Yoshiro Horai3 and Atsushi Kawakami4, 1Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 2Department of Rheumatology, Japan Community Healthcare Organization (JCHO) Isahaya General Hospital, Isahaya, Japan, 3Department of Rheumatology, Sasebo City General Hospital, Sasebo, Japan, 4Nagasaki University, Nagasaki, Japan

    Background/Purpose: Avacopan, a C5a receptor inhibitor, has emerged as a novel treatment for ANCA-associated vasculitis (AAV), providing an alternative to glucocorticoids1. Despite its promising potential,…
  • Abstract Number: 0203 • ACR Convergence 2024

    Agreement of Administrative Pharmacy Dispensing with Patient-Reported Use of Oral Glucocorticoids in a Rheumatoid Arthritis Cohort

    Beth Wallace1, Bryant England2, Joshua Baker3, Sauer brian4, Jorge Rojas5, Punyasha Roul6, Michael George7, Katherine Wysham8, Hannah Brubeck9, Isaac Smith10, Liron Caplan11, Paul Monach12, Gail Kerr13, Gary Kunkel14, Tawnie Braaten15, Ted Mikuls2 and grant Cannon16, 1Michigan Medicine, VA Ann Arbor Healthcare System, Ann Arbor, MI, 2University of Nebraska Medical Center, Omaha, NE, 3Department of Medicine, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, 4Salt Lake City VA/University of Utah, Salt Lake City, UT, 5Seattle VA, Mexico, Mexico, 6UNMC, Omaha, NE, 7University of Pennsylvania, Philadelphia, PA, 8VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 9VA Puget Sound Health Care System, Seattle, WA, 10Duke Department of Medicine; VA Durham Healthcare System, Durham, NC, 11Univ of Colorado School of Medicine/Rocky Mtn Regional Veterans Affairs Medical Center, Aurora, CO, 12VA Boston Healthcare System, Boston, MA, 13Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, 14University of Utah/VA Salt Lake City Health Care, Salt Lake City, UT, 15UNIVERSITY OF UTAH, Salt Lake City, UT, 16University of Utah and Salt Lake City VA, Salt Lake City, UT

    Background/Purpose: Administrative claims are often used to evaluate oral glucocorticoid (GC) use in RA for clinical and research purposes, despite limited evidence to support their…
  • Abstract Number: 1483 • ACR Convergence 2024

    Real World Data on Infections from the Indian SLE Inception Cohort for Research (INSPIRE): Spectrum and Risk Factors

    SAUMYA TRIPATHY1, DEBASISH PANDIT2, Sarit Pattanaik3, Liza Rajasekhar4, VINEETA SHOBHA5, Chengappa Kavadichanda6, Ashish J Mathew7, Parasar Ghosh8, Ranjan Gupta9, Manish Rathi10, AVINASH JAIN11, MANOJ PARIDA12, Bidyut Das13 and Amita Aggarwal14, 1SCB Medical College, Cuttack, Odisha, India, Cuttack, Orissa, India, 2SJM MCH, Puri, Puri, Orissa, India, 3SCB Medical College and Hospital, Cuttack, Odisha, Cuttack, Orissa, India, 4Nizam's Institute of Medical Sciences, Madhapur, Andhra Pradesh, India, 5ST JOHN'S MEDICAL COLLEGE, BENGALURU, Karnataka, India, 6Jawaharlal Institute of Postgraduate Medical Education and Research, pondicherry, Puducherry, India, 7Christian Medical College, Vellore, Tamil Nadu, India, 8Govt of West Bengal, Kolkata, India, Kolkata, West Bengal, India, 9All India Institute of Medical Sciences, New Delhi, Delhi, India, 10Postgraduate Institute of Medical Education & Research, Chandigarh, Chandigarh, India, 11SMS MCH, JAIPUR, JAIPUR, Rajasthan, India, 12SCB MEDICAL COLLEGE, CUTTACK, Cuttack, Orissa, India, 13SCB Medical College, Cuttack, Orissa, India, 14Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India

    Background/Purpose: Infections in SLE are a major cause of morbidity and mortality. The susceptibility to infections in SLE is multifactorial. Immune dysregulation, immunosuppressive drug use and…
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