ACR Meeting Abstracts

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Abstracts tagged "geriatrics"

  • Abstract Number: 0858 • ACR Convergence 2024

    Baricitinib in Early Polymyalgia Rheumatica (BACHELOR Study)

    Alain SARAUX1, Guillermo CARVAJAL ALEGRIA2, Emmanuelle Dernis3, christian roux4, Christophe Richez5, Alice TISON6, Baptiste Quere7, Sandrine Jousse-Joulin8, Dewi Guellec7, Thierry Marhadou9, Patrice Kervarrec7, Divi Cornec10, Catherine Le Henaff7, Sandra Lesven7, nowak emmanuel7, Aghiles Souki7 and Valerie Devauchelle11, 1CHU Brest, Brest, France, 2CHRU de Tours, Tours, France, 3CH LE MANS, LE MANS, Pays de la Loire, France, 4rheumatology department, university Cote d'Azur, nice, France, 5Université de Bordeaux, Bordeaux, France, 6CHU de la Cavale Blanche, Brest, France, Brest, France, 7Centre Hospitalier Regional Universitaire (CHU) de Brest, Brest, France, 8cavale blanche hospital, brest, France, 9CHU Cavale Blanche, Brest, France, 10University of Brest, Brest, France, 11UBO, Brest, France

    Background/Purpose: Moderate glucocorticoids (GCs) improve nearly all cases of polymyalgia rheumatica (PMR) but related adverse events are common in senior patients.  The purpose of this…
  • Abstract Number: 0992 • ACR Convergence 2024

    Visceral Adipose Tissue Measured by DXA Predicts Metabolic Syndrome in Low-Income Community-Dwelling Elderly: Insights from the São Paulo Ageing & Health (SPAH) Study

    Gabriel Vansuita Valente1, Luana Machado1, Andre Franco2, Valeria Caparbo1, Liliam Takayama3, Alan Lins Fernandes1, Camille Figueiredo1, Rosa M R Pereira1 and Diogo Domiciano2, 1Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR., São Paulo, SP, Brazil, 2Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 3Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, São Paulo, SP, Brazil

    Background/Purpose: To establish optimal cutoffs for visceral adipose tissue (VAT) to predict cardiometabolic risk in a low-income elderly Brazilian cohort, utilizing dual-energy X-ray absorptiometry (DXA)…
  • Abstract Number: 1213 • ACR Convergence 2024

    High Prevalence of and Medication Use in Musculoskeletal and Chronic Multisite Pain in Community-Dwelling Older Adults: The Framingham Heart Study

    Sayali Dhamne1, Robert Edwards2, Emelia Benjamin3, Sarah Tilley3, Angelo Demalia4, Margaret Clancy3, Mary Molly Gheller3 and Tuhina Neogi3, 1Boston University Chobantian & Avedisian School of Medicine, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 4Framingham Heart Study, Boston, MA

    Background/Purpose: Over 100 million adults have chronic pain, largely affecting older adults who often have >1 chronic pain condition. Traditionally, chronic overlapping pain conditions (COPC)…
  • Abstract Number: 1698 • ACR Convergence 2024

    Assessment of the Remission Maintenance After Tocilizumab Withdrawal in Polymyalgia Rheumatica Patients Receiving a 6-month Treatment

    Baptiste Chevet1, Aghiles Souki2, nowak emmanuel2, Guillermo CARVAJAL ALEGRIA3, Emmanuelle Dernis4, Christophe Richez5, Marie-Elise Truchetet6, DANIEL WENDLING7, ERIC TOUSSIROT8, aleth Perdriger9, Jacques-Eric Gottenberg10, Renaud FELTEN11, Bruno Fautrel12, laurent chiche13, Anne Walliser-Lohse14, Pascal Hilliquin15, Catherine Le Henaff16, Benjamin Dervieux17, Guillaume Direz18, Isabelle Valckenaere19, Divi Cornec20, Dewi Guellec21, Thierry Marhadou22, Alain SARAUX23 and Valerie Devauchelle24, 1University Hospital of Brest, Brest, France, 2Centre Hospitalier Regional Universitaire (CHU) de Brest, Brest, France, 3CHRU de Tours, Tours, France, 4CH LE MANS, LE MANS, Pays de la Loire, France, 5Université de Bordeaux, Bordeaux, France, 6Bordeaux University Hospital, Bordeaux, France, 7University Hospital, Besançon, France, 8university hospital of BESANCON, besancon, France, 9Rennes University, Rennes, France, 10Rheumatology Department, Strasbourg University Hospital,, Strasbourg, France, 11Hopitaux Universitaires de Strasbourg, STRASBOURG, France, 12INSERM, UMRS 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Sorbonne University – Assistance Publique-Hôpitaux de Paris, Département de Rhumatologie, Hôpital Pitié-Salpêtrière, Paris, Ile-de-France, France, 13hopital europeen, marseille, France, 14Hopital Nord Franche-Comté, BELFORT, France, 15Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France, 16Hopital de Morlaix, Morlaix, France, 17CH de Mulhouse - Competence center for autoimmune diseases, Internal Medicine, Mulhouse, France, 18Hôpital du Mans, Le Mans, France, 19CHU de Nancy, Nancy, France, 20Service de Rhumatologie, CHU de Brest, Brest, France, 21CHU de Brest, Brest, France, 22CHU Cavale Blanche, Brest, France, 23CHU Brest, Brest, France, 24UBO, Brest, France

    Background/Purpose: The SEMAPHORE trial1 was a randomized controlled prospective study to assess the safety and efficacy (success defined by PMR-AS≤10 and GC≤5mg or GC decrease…
  • Abstract Number: 0686 • ACR Convergence 2023

    Safety and Efficacy of Avacopan in Patients 65 Years and Older with ANCA-Associated Vasculitis

    David Jayne1, Duvuru Geetha2, Christian Pagnoux3, Sebastian Sattui4 and Peter Merkel5, 1University of Cambridge, Cambridge, United Kingdom, 2Johns Hopkins University, Baltimore, MD, 3Mount Sinai Hospital, Toronto, ON, Canada, 4University of Pittsburgh, Pittsburgh, PA, 5University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Older adults are at increased risk of glucocorticoid (GC)-related toxicity; minimization of GCs is a major focus for treatment of patients with ANCA-associated vasculitis…
  • Abstract Number: 1288 • ACR Convergence 2023

    Frailty Is Associated with Higher Risk of Readmission in Patients with Rheumatoid Arthritis

    Waqas Tahir1, Yenny Rosli2, Christopher Leung3, K Wysham4, Jiha Lee5, Radjiv Goulabchand6, Una Makris7, Siddharth Singh8 and Namrata Singh9, 1Mayo Clinic, Jacksonville, FL, 2University of Washington, Seattle, WA, 3Georgetown University School of Medicine, Washington, DC, 4VA Puget Sound/University of Washington, Seattle, WA, 5University of Michigan, Ann Arbor, MI, 6University of California San Diego, La Jolla, CA, 7UT Southwestern Medical Center and Dallas VA, Dallas, TX, 8University of California San Diego, San Diego, CA, 9University of Washington, Bellevue, WA

    Background/Purpose: With the advent of new therapies and increasing life expectancy, there is a rising number of older adults living with rheumatoid arthritis (RA). Patients…
  • Abstract Number: 0062 • ACR Convergence 2022

    Comparing Alzheimer’s Disease Risk in Patients with Chronic Inflammatory Autoimmune Diseases: A Medicare Cohort Study

    Justin Levinson1, Jonathan Katz2, Yi Chen3, W. Ryan Powell4, Andrea Gilmore-Bykovskyi5, Amy J. Kind6 and Christie Bartels7, 1University of Wisconsin School of Medicine and Public Health, Department of Medicine, Rheumatology Division, Madison, WI, 2University of Wisconsin Hospitals and Clinics, Madison, WI, 3University of Wisconsin School of Medicine and Public Health, Department of Medicine, Department of Biostatistics and Informatics, Madison, WI, 4University of Wisconsin School of Medicine and Public Health, Center for Health Disparities Research, Thousand Oaks, CA, 5University of Wisconsin School of Medicine and Public Health, Department of Emergency Medicine; and the Center for Health Disparities Research, Madison, WI, 6University of Wisconsin School of Medicine and Public Health, Department of Medicine, Geriatrics Division & Center for Health Disparities Research, Madison, WI, 7University of Wisconsin School of Medicine and Public Health, Madison, WI

    Background/Purpose: Chronic inflammatory diseases have been associated with an increased risk of Alzheimer’s disease (AD), yet emerging research in rheumatoid arthritis (RA) and psoriasis suggests…
  • Abstract Number: 1584 • ACR Convergence 2022

    Colchicine or Prednisone for the Treatment of Acute Calcium Pyrophosphate Deposition Arthritis: A Multicenter Randomized Controlled Trial

    Tristan Pascart1, Pierre Robinet2, Sebastien Ottaviani3, Remi Leroy4, Nicolas Segaud5, Aurore Pacaud2, Hélène Luraschi2, Thibault Rabin2, Agathe Grandjean2, Xavier Deplanque6, Pierre Maciejasz6, Fabien Visade2, Alexandre Mackowiak2, Nicolas Baclet6, Antoine Lefebvre2, Jean-François Budzik2, Thomas Bardin7, Pascal Richette8, Laurène Norberciak2, Vincent Ducoulombier2 and Eric Houvenagel1, 1Groupement Hospitalier de l'Institut Catholique de Lille, Lomme, France, 2Hôpital Saint-Philibert, Lomme, France, 3Hopital Bichat-Claude Bernard, Paris, France, 4Centre Hospitalier de Dunkerque, Dunkerque, France, 5Centre Hospitalier d'Armentières, Armentières, France, 6Hôpital Saint-Vincent-de-Paul, Lille, France, 7Hôpital Lariboisiere, Paris, France, 8Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France

    Background/Purpose: Treatment of acute CPP arthritis mainly relies on expert opinion, as there are no trials that assessed the efficacy of anti-inflammatory drugs, despite the…
  • Abstract Number: 1715 • ACR Convergence 2022

    Ezh2 Knockout in B Cells Impairs Plasmablast Differentiation and Ameliorates Lupus-like Disease in MRL/lpr Mice

    Xiaoqing Zheng1, Mikhail Dozmorov2, Colleen Strohlein1, Sheldon Bastacky1 and Amr Sawalha1, 1University of Pittsburgh, Pittsburgh, PA, 2Virginia Commonwealth University, Richmond, VA

    Background/Purpose: Enhancer of zeste homolog 2 (EZH2) has been shown to regulate early B cell development and the differentiation of antibody secreting cells (ASCs). We…
  • Abstract Number: 0536 • ACR Convergence 2020

    Systematic Geriatric Assessment in Older Patients with Rheumatic Diseases – The RheuMAGIC Pilot Study

    Bjoern Buehring1, Anna Berrisch2, Ioana Andreica3, Styliani Tsiami4, David Kiefer3, Uta Kiltz2, Xenofon Baraliakos2 and Juergen Braun2, 1Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Velbert, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Current demographic data predict that the number of older adults with rheumatic diseases will considerably increase in the coming years. Geriatric patients differ from…
  • Abstract Number: 0695 • ACR Convergence 2020

    Chronic Inflammatory Back Pain Occurring Later in Life: A Neglected Concept

    Lauren Ridley1, Nahid Rianon2, Mark Hwang3, MinJae Lee4, Lianne Gensler5, Michael Ward6, Matthew Brown7, Amirali Tahanan2, Mohammad Rahbar2, Mariko Ishimori8, Michael Weisman9 and John Reveille10, 1McGovern Medical School at UTHealth, Houston, TX, 2McGovern Medical School at UTHealth, Houston, 3McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, 4UT Southwestern, Dallas, 5University of California San Francisco, San Francisco, CA, 6National Institutes of Health, Bethesda, MD, 7Guy's and St Thomas, NHS Foundation Trust and King's College London NIHR Biomedical Research Centre, King's College London, London, United Kingdom, London, United Kingdom, 8Cedars-Sinai Medical Center, Los Angeles, CA, 9Distinguished Professor of Medicine Emeritus, David Geffen School of Medicine at UCLA, LOS ANGELES, CA, 10Department of Internal Medicine, University of Texas, Houston, TX

    Background/Purpose: Chronic back pain (CBP) is a common musculoskeletal complaint and a significant cause of disability (Weisman et al., 2013). A subset of CBP, chronic…
  • Abstract Number: 0807 • ACR Convergence 2020

    Safety of Biologic & Targeted Therapies Among Elderly Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis

    Akhil Sood1, Soham Al Snih1, Vijaya Murthy2, Emilio Gonzalez1 and Mukaila Raji1, 1University of Texas Medical Branch, Galveston, TX, 2University of Texas Medical Branch, League City, TX

    Background/Purpose: Recent developments in biologic and targeted therapy have led to better control of disease activity and improved quality of life in patients with rheumatoid…
  • Abstract Number: 1710 • 2018 ACR/ARHP Annual Meeting

    Polypharmacy in Older Adults with Systemic Lupus Erythematosus

    Dale Seguin1, Christine A. Peschken2, Ruby Grymonpre3, Phil St. John4 and Annaliese Tisseverasinghe5, 1Internal Medicine, University of Manitoba, Winnipeg, MB, Canada, 2RR 149G, University of Manitoba, Winnipeg, MB, Canada, 3College of Pharmacology, University of Manitoba, Manitoba, MB, Canada, 4Geriatrics, University of Manitoba, Winnipeg, MB, Canada, 5Rheumatology, University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Polypharmacy is a strong risk factor for drug toxicity and adverse clinical outcomes, including delirium, falls, hospitalizations, and death. Polypharmacy is correlated with the…
  • Abstract Number: 2755 • 2016 ACR/ARHP Annual Meeting

    Comparison of Clinical Profile of Geriatric and Non-Geriatric Ankylosing Spondylitis (AS) Patients

    Ahmed Omar1, Laura Passalent2, Renise Ayearst3, Ismail Sari1, Anthony V. Perruccio4, Rajiv Gandhi5, Nigil Haroon1 and Robert D Inman1, 1Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 2Allied Health, Toronto Western Hospital, Toronto, ON, Canada, 3Medicine, University Health Network, Toronto, ON, Canada, 4Health Care & Outcomes Research, Krembil Research Institute, University Health Network, Toronto, ON, Canada, 5Department of Surgery - Orthopedics, Toronto Western Hospital, Assistant Professor, Department of Surgery, University of Toronto​, Toronto, ON, Canada

    Background/Purpose: Data on disease characteristics of geriatric patients (>=65 years) with AS are lacking. The objective of this study is to compare: 1) the clinical…
  • Abstract Number: 2163 • 2015 ACR/ARHP Annual Meeting

    Associations Between Sex Differences, Pain, Insomnia, and Depression in Older Adults with Osteoarthritis: A Cross-Sectional Study

    Minhui Liu1, Susan McCurry1, Michael Vitiello2, Basia Belza1 and Michael Von Korff3, 1University of Washington School of Nursing, Seattle, WA, 2Psychiatry and Behavioral Sciences, Biobehavioral Nursing and Health Systems, University of Washington School of Medicine, Seattle, WA, 3Group Health Research Institute, Seattle, WA

    Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis and affects nearly 30 million Americans. Chronic pain is the major symptom in OA and…
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