ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstracts tagged "genomics and rheumatoid arthritis"

  • Abstract Number: 995 • 2012 ACR/ARHP Annual Meeting

    Genetic Effects of HLA-DRB1, IL4R, and FcγRIIb On Long-Term Treatment Responses in Patients with Early Rheumatoid Arthritis: 78-Week Results of a Phase 4 Study

    Alla Skapenko1, Josef S. Smolen2, Arthur Kavanaugh3, Vipin Arora4, Hartmut Kupper5 and Hendrik Schulze-Koops6, 1Division of Rheumatology and Clinical Immunology, Med. Poliklinik,, University of Munich, Munich, Germany, 2Department of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 3UCSD School of Medicine, La Jolla, CA, 4Health Outcomes Research, Abbott, Abbott Park, IL, 5Immunology Development, Abbott GmbH and Co. KG, Ludwigshafen, Germany, 6University of Munich, Munich, Germany

    Background/Purpose: Previous analyses suggested that the HLA-DRB1 shared epitope (SE), and the IL4R V50I and the FcγRIIb I232T single nucleotide polymorphisms (SNPs) affected response to…
  • Abstract Number: 1298 • 2012 ACR/ARHP Annual Meeting

    Improvement of Treatment Outcome of Rheumatoid Arthritis with Salazosulfapyridine by Pharmacogenetic Approach

    Shunichi Kumagai1, Yoshiaki Hagiwara2, Yoshihide Ichise1, Sho Sendo3, Nobuhiko Okada1, Jun Saegusa4 and Goh Tsuji5, 1Center of rheumatic diseases, Shinko hospital, Kobe, Japan, 2Department of Evidence-Based Laboratory Medicine, Kobe University Graduate School of Medicine, Kobe, Japan, 3Center of rheumatic diseases, Shinko Hospital, Kobe, Japan, 4Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, 5Center for Rheumatic Diseases, Shinko Hospital, Kobe, Japan

    Background/Purpose: Salazosulfapyridine (SASP) is acetylated in liver by N-acetyltransferase2 (NAT2) in the track of metabolism. Previous studies have shown that genotyping of NAT2 is adequate…
  • Abstract Number: 1595 • 2012 ACR/ARHP Annual Meeting

    Genome-Wide Association Study to High -Throughput Cell-Based Phenotypic Screen Identifies Novel Chemical Inhibitors of CD40 Signaling

    Gang Li1, Dorothee Diogo2, Di Wu1, Jim Spoonamore3, Rheumatoid Arthritis Consortium International (RACI)4, Eli Stahl5, Nicola Tolliday3 and Robert M. Plenge6, 1Division of Rheumatology, Immunology and Allergy and Division of Genetics, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 3Broad Institute, Cambridge, MA, 4Boston, 5Brigham and Women's Hospital, 6Division of Rheumatology, Immunology and Allergy and Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Deriving therapeutic targets from human genetics linked with biological alterations of risk alleles may provide a more successful approach to drug development than traditional…
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

ACR Pediatric Rheumatology Symposium 2020

© COPYRIGHT 2023 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences