Abstracts tagged "genomics and osteoarthritis"

Abstract Number: 994 • 2012 ACR/ARHP Annual Meeting
The Genome-Wide Expression of Human Osteoarthritic Cartilage Shows A Differential Pattern Between Two Subgroups of OA Patients
Ignacio Rego-Perez¹, Juan Fernandez-Tajes¹, Angel Soto-Hermida², Mercedes Fernandez Moreno¹, Maria Eugenia Vazquez Mosquera³, Natividad Oreiro¹, Carlos Fernandez-Lopez¹, Estefania Cortes Pereira¹, Sara Relaño-Fernandez¹ and Francisco J. Blanco¹, ¹INIBIC-Hospital Universitario A Coruña. Genomic Group. Rheumatology Division., A Coruña, Spain, ²INIBIC-Hospital Universitario A Coruña. Rheumatology Division. Genomic Group, A Coruña, Spain, ³Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain
Background/Purpose: Many genes, many of them still unknown, are involved in the etiology and development of OA. Today, different tools are available to try to…
Abstract Number: 731 • 2012 ACR/ARHP Annual Meeting
A Systems Biology Approach to Elucidating Pathways Active During the Development of Osteoarthritis
Richard F. Loeser¹, Amy L. Olex², Brian Westwood², Margaret A. McNulty³, Cathy S. Carlson³, Michael Callahan⁴, Cristin Ferguson⁴ and Jacquelyn S. Fetrow², ¹Section Of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, ²Computer Science, Wake Forest University, Winston-Salem, NC, ³Veterinary and Diagnostic Medicine, University of Minnesota, St. Paul, MN, ⁴Orthopedic Surgery, Wake Forest School of Medicine, Winston-Salem, NC
Background/Purpose: OA affects the entire joint but most studies have focused on the disease process in a single tissue. In this study, we identified genes…

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