Abstracts tagged "genomics and joint destruction"

Abstract Number: 973 • 2012 ACR/ARHP Annual Meeting
New Genetic Risk Loci for the Radiographic Severity of Rheumatoid Arthritis
Diederik P.C. de Rooy¹, Sacha Zhernakova¹, Roula Tsonaka², Fina Kurreeman³, René E.M. Toes¹, Tom W. J. Huizinga⁴, Jeanine Houwing-Duistermaat⁵, Peter K. Gregersen⁶ and Annette H.M. van der Helm-van Mil¹, ¹Rheumatology, Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Medical Statistics, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Department of Rheumatology, Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Statistics, Statistics, Leiden University Medical Center, Leiden, Netherlands, ⁶Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: The severity of joint destruction is highly variable between Rheumatoid Arthritis (RA) patients; approximately 54% of this variance is explained by genetic factors. Many…

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