Abstracts tagged "genetics and spondylarthropathy"

Abstract Number: 107 • 2015 ACR/ARHP Annual Meeting
FCGR3A-158V/F Polymorphism Is Associated with a Lower Response Rate to Tumor Necrosis FactorÂ Î± Blockers in Early Axial Spondyloarthritis: Data from the DESIR Cohort
Cécile LUXEMBOURGER¹, Anna Molto², Pascal Claudepierre³, Delphine Nigon¹, Alain G. Cantagrel¹, Maxime Dougados⁴, Arnaud CONSTANTIN¹ and Adeline Ruyssen Witrand⁵, ¹Rheumatology, CHU Purpan - Hôpital Pierre-Paul Riquet, Toulouse, France, ²Hopital Cochin, Paris Descartes University, Paris, France, ³Hôpital Henri Mondor, Créteil, France, ⁴Service de Rhumatologie B, GHU Cochin, F-75014 France, PARIS, France, ⁵Rheumatolgy, CHU Purpan - Hôpital Pierre-Paul Riquet, Toulouse, France
Background/Purpose: The rs396991 polymorphism of FCGR3A alters the Fcγ Receptor Type IIIA function by enhancing or diminishing the affinity to the Fc of immunoglobulins (1)…