Abstracts tagged "genetics and psoriatic arthritis"

Abstract Number: 100 • 2015 ACR/ARHP Annual Meeting
Validation of a Distinct Psoriatic Arthritis Risk Variant at IL23R
Ashley Budu-Aggrey^1,2, John Bowes¹, Sabine Lohr³, Maria I. Zervou⁴, Philip S. Helliwell⁵, Anthony W. Ryan⁶, David Kane⁷, Eleanor Korendowych⁸, Emiliano Giardina⁹, Jonathon Packham¹⁰, Ross McManus⁶, Oliver FitzGerald¹¹, Neil J McHugh⁸, Frank Behrens¹², Harald Burkhardt¹², Ulrike Huffmeier³, Javier Martín¹³, George Goulielmos⁴, Pauline Ho^1,14, Andre Reis³ and Anne Barton^1,2,14, ¹Arthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academy of Health Sciences, Manchester, United Kingdom, ³Institute of Human Genetics, University of Erlangen-Nuremberg, Erlangen, Germany, ⁴Laboratory of Molecular Medicine and Human Genetics, Department of Internal Medicine, University of Crete, Heraklion, Greece, ⁵NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, ⁶Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland, ⁷Adelaide and Meath Hospital and Trinity College Dublin, Dublin, United Kingdom, ⁸Royal National Hospital for Rheumatic Diseases and Dept Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom, ⁹Department of Biopathology, Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome 'Tor Vergata' and Fondazione PTV 'Policlinico Tor Vergata', Rome, Italy, ¹⁰Rheumatology department, Haywood Hospital, Health Services Research Unit, Institute of Science and Technology in Medicine, Keele University, Staffordshire, United Kingdom, ¹¹Department of Rheumatology, St. Vincent’s University Hospital, UCD School of Medicine and Medical Sciences and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland, ¹²Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt, Germany, ¹³Instituto de Biomedicina y Parasitología López-Neyra, Granada, Spain, ¹⁴The Kellgren Centre for Rheumatology, Central Manchester Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom
Background/Purpose: Psoriatic Arthritis (PsA) is an inflammatory arthritis that is associated with psoriasis. In the UK, it is estimated to present in approximately 14% of…
Abstract Number: 537 • 2013 ACR/ARHP Annual Meeting
Investigating a Novel Locus For Psoriatic Arthritis
Ashley Budu-Aggrey^1,2, John Bowes¹, Pauline Ho^1,3, James Bluett¹, Harry Hébert^1,4, Helena Marzo-Ortega⁵, Ann W. Morgan⁶, Matthew A. Brown⁷, Ross McManus⁸, Neil McHugh⁹, Oliver FitzGerald¹⁰, Ian N. Bruce^2,11,12 and Anne Barton^1,2, ¹Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, Manchester, United Kingdom, ³NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Manchester, United Kingdom, ⁴The Dermatology Centre, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, ⁵LMBRU, Chapel Allerton Hospital, and University of Leeds, Leeds, United Kingdom, ⁶NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Human Genetics Group, The University of Queensland Diamantina Insititute, Brisbane, Australia, ⁸Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, Ireland, Dublin, Ireland, ⁹Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ¹⁰Department of Rheumatology, St.Vincent's University Hospital, Dublin, Ireland, ¹¹Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ¹²Kellgren Centre for Rheumatology, Central Manchester University Hospitals Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom
Background/Purpose: Psoriatic arthritis (PsA) is a complex genetic disorder with a prevalence of up to 1% in the general population. The association of PsA with…

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