Abstracts tagged "Genetics and juvenile arthritis"

Abstract Number: 1970 • ACR/ARHP Annual Meeting 2018
Linking Genetics to T Cell Phenotype in JIA: Rationale for IL-2 Therapy
Annie Yarwood¹, Samantha Smith¹, Stephen Eyre² and Wendy Thomson³, ¹Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, United Kingdom, ³Arthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom
Background/Purpose: Several genetic regions associated with susceptibility to juvenile idiopathic arthritis (JIA), harbour genes involved in the interleukin-2 (IL-2) response which is pivotal in the…