Abstracts tagged "genetics and integrative"

Abstract Number: 916 • 2018 ACR/ARHP Annual Meeting
Integrative Analysis of Multi-Omics Data in an Ethnically Diverse Lupus Cohort Identifies Distinct Molecular Subtypes of SLE
Cristina Lanata¹, Ishan Paranjpe², Joanne Nitiham³, Kimberly Taylor⁴, Brooke Rhead⁵, Milena Gianfrancesco⁶, Lisa Barcellos⁷, Louise Murphy⁸, Patricia Katz⁹, Laura Trupin⁶, Jinoos Yazdany², Maria Dall'Era², Marina Sirota¹⁰ and Lindsey A. Criswell⁹, ¹Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, Division of Rheumatology, University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA, ³Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA, ⁴University of California, San Francisco, Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, San Francisco, CA, ⁵University of California, Berkeley, Berkeley, CA, ⁶Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁷School of Public Health, UC Berkeley, Berkeley, CA, ⁸Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ⁹University of California San Francisco, San Francisco, CA, ¹⁰Pediatrics, Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, CA
Background/Purpose: Systemic Lupus Erythematous (SLE) is a chronic autoimmune disease with heterogeneous disease manifestations and outcomes. We aimed to define how molecular differences underlie this…

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